PROTAC-DB is a public, web-accessible database. The chemical structures, biological activities, physiochemical properties of these compounds are manually extracted from the literature or calculated by some programs. Here, the biological activities of PROTACs contain the degradation capacity, binding affinities and cellular activities.
CovalentInDB (Covalent Inhibitor Database) is the largest web-accessible resource for covalent inhibitors and related targets. The latest version provides the information for 4806 covalent inhibitors and 298 related protein targets collected by comprehensive literature searching. The inhibitors in CovlnDB possess 57 types of reactive warheads, including Michael acceptor, beta lactam, boronic acid, epoxide, halohydrocarbon, etc.
CovalentInDB provides not only the basic information of covalent inhibitors, targets, and bioactivity, but also the reactive warheads of inhibitors, covalent reaction mechanism, attacked nucleophilic residues and covalent-mechanism experimental verification methods. A molecular visualization function is also embedded to display protein-ligand interaction. Moreover, CovalentInDB also provides the structural transformation process during the covalent reaction for each warhead.
We have established the first dedicated single domain antibody repository and database. The database hosts a large collection of natural and synthetic camelid single domain antibody sequences from literature sources, other online repositories (PDB and NCBI), and manual entries from users.
The ABCD (AntiBodies Chemically Defined) database is a manually curated depository of sequenced antibodies, developed by the Geneva Antibody Facility at the University of Geneva, in collaboration with the CALIPHO and Swiss-Prot groups at SIB Swiss Institute of Bioinformatics.
EastCoast Bio is a manufacturer and supplier of high quality antigens, antibodies, our exclusive SeaBlock, and specialized immunoassay reagents for the in vitro diagnostic (IVD) manufacturing industry worldwide.
Creative Biolabs is specialized in providing custom biotechnology and pharmaceutical services that cover the full scope of biotechnology needs of drug …
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