Cohort reference publications
[National Precision Medicine] Wong E et al. The Singapore National Precision Medicine Strategy. Nat Genet. 2023 Feb;55(2):178-186.
[CHS_T1] Chan TK et al. Cancer Screening Knowledge and Behaviour in a Multi-Ethnic Asian Population: The Singapore Community Health Study. Front Oncol. 2021 Aug 12;11:684917.
[MEC2_T1] Whitton C et al. Longitudinal Associations of Marital, Parenting, and Employment Transitions with Weight Gain in a Multi-Ethnic Asian Population Aged 21 Years and Above. Int J Environ Res Public Health. 2021 Jul 31;18(15):8115.
[DC_T1] Luo M et al. Cohort profile: the Singapore diabetic cohort study. BMJ Open 2020;10:e036443.
[MEC1_T1] Tan KHX et al. Cohort Profile: The Singapore Multi-Ethnic Cohort (MEC) study. Int J Epidemiol. 2018 Jun 1;47(3):699-699j.
[SH2_T1] Vaingankar J et al. Psychometric properties and population norms of the Positive Mental Health instrument in a representative multi-ethnic Asian population. BMC Med Res Methodol. 2018 Mar 15;18(1):29.
[SH2012_T1] Win AM et al. Patterns of physical activity and sedentary behavior in a representative sample of a multi-ethnic South-East Asian population: a cross-sectional study. BMC Public Health. 2015 Apr 1;15:318.
All publications
2024
274. NCD Risk Factor Collaboration (NCD-RisC). General and abdominal adiposity and hypertension in eight world regions: a pooled analysis of 837 population-based studies with 7·5 million participants. Lancet. 2024 Aug 31;404(10455):851-863.
273. Lim GH et al. Dietary Patterns and Cardiovascular Diseases in Asia: A Systematic Review and Meta-Analysis. Adv Nutr. 2024 Jul;15(7):100249.
272. Tan LF et al. Prevalence of tight glycemic control based on frailty status and associated factors in community-dwelling older adults. Postgrad Med J. 2024 Jun 27:qgae077.
271. Fauzi NBM et al. Association of a healthy ageing index with health-related outcomes in a multi-ethnic cohort from Singapore. BMC Geriatr. 2024 Jun 11;24(1):508.
270. Whitton C et al. Ecological momentary assessment of digital food and beverage marketing exposure and impact in young adults: A feasibility study. Appetite. 2024 Jun 1;197:107338.
269. Ho PJ et al. Characterizing the Relationship between Expression Quantitative Trait Loci (eQTLs), DNA Methylation Quantitative Trait Loci (mQTLs), and Breast Cancer Risk Variants. Cancers (Basel). 2024 May 30;16(11):2072.
268. Chia A et al. Complexity of consumer acceptance to alternative protein foods in a multiethnic Asian population: A comparison of plant-based meat alternatives, cultured meat, and insect-based products, Food Quality and Preference, Volume 114, May 2024.
267. Lee MY et al. Association between Marital Status and Cognitive Impairment in a Multi-Ethnic Asian Population. Neuroepidemiology. 2024 Mar 14.
266. Guirette M et al. Genome-Wide Interaction Analysis with DASH Diet Score Identified Novel Loci for Systolic Blood Pressure. Hypertension. 2024 Mar;81(3):552-560.
265. Suzuki K et al. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. 2024 Feb 19.
264. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults. Lancet. 2024 Feb 29:S0140-6736(23)02750-2.
263. Scholz M et al. X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. Nat Commun. 2024 Jan 18;15(1):586.
2023
262. Lim SX et al. Development and validation of a lifestyle risk index to screen for metabolic syndrome and its components in two multi-ethnic cohorts. Prev Med. 2023 Dec 18:107821
261. Feng Z et al. Associations of childhood and current secondhand smoke exposure at home with current secondhand smoke exposure at work: A cross-sectional analysis of the Singapore multi-ethnic cohort. Tob Induc Dis. 2023 Dec 15;21:169.
260. Chan CMJ et al. Understanding knowledge, attitudes and behaviours related to dietary sodium intake in a multi-ethnic population in Singapore. Public Health Nutr. 2023 Dec;26(12):2802-2814.
259. Huang J et al. Association of diet quality with hand grip strength weakness and asymmetry in a multi-ethnic Asian cohort. Br J Nutr. 2023 Nov 22:1-8
258. de Las Fuentes L et al. Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci. Front Genet. 2023 Nov 2;14:1235337.
257. Lim CGY et al. RECALIBRATED SINGAPORE-MODIFIED FRAMINGHAM RISK SCORE 2023 (SG-FRS-2023). [Report]
256. Ang IYH et al. Preferences and willingness-to-pay for a blood pressure telemonitoring program using a discrete choice experiment. NPJ Digit Med. 2023 Sep 25;6(1):176.
255. Seah JYH et al. Risk prediction models for type 2 diabetes using either fasting plasma glucose or HbA1c in Chinese, Malay, and Indians: Results from three multi-ethnic Singapore cohorts. Diabetes Res Clin Pract. 2023 Aug 15;203:110878.
254. Park SH et al. Acculturation as a Determinant of Obesity and Related Lifestyle Behaviors in a Multi-Ethnic Asian Population. Nutrients. 2023 Aug 17;15(16):3619.
253. Seah JYH et al. Differences in type 2 diabetes risk between East, South, and Southeast Asians living in Singapore: the multi-ethnic cohort. BMJ Open Diabetes Res Care. 2023 Jul;11(4):e003385.
252. Ge L et al. Association Between Domain-Specific Physical Activity and Cardiometabolic Factors in a Multiethnic Asian Population: A Longitudinal Study. J Phys Act Health. 2023 May 8:1-14.
251. Xu Y et al. An atlas of genetic scores to predict multi-omic traits. Nature. 2023 Apr;616(7955):123-131.
250. Huang X et al. Association between nutrition and cognition in a multi-ethnic cohort from Singapore. Eur J Nutr. 2023 Apr 27.
249. Lee et al. Isocaloric substitution of plant-based protein for animal-based protein and cardiometabolic risk factors in a multi-ethnic Asian Population. J Nutr. 2023 Mar 22.
248. Goh AT et al. Associations between oral processing, saliva, and bolus properties on daily glucose excursions amongst people at risk of type-2 diabetes. Food Funct. 2023 Feb 21;14(4):2260-2269.
247. Wong E et al. The Singapore National Precision Medicine Strategy. Nat Genet. 2023 Feb;55(2):178-186.
246. Rooney MR et al. Proteomic Predictors of Incident Diabetes: Results From the Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care. 2023 Jan 27:dc221830.
245. Diocom AR et al. Association between Shift Work Schedules and Cardiovascular Events in a Multi-Ethnic Cohort. Int J Environ Res Public Health. 2023 Jan 22;20(3):2047.
2022
244. Huang X et al. Handgrip Strength and Cognitive Performance in a Multiethnic Cohort in Singapore. J Alzheimers Dis. 2022;90(4):1547-1555.
243. Yin X et al. Dietary factors and the risk of lung cancer by epidermal growth factor receptor mutation status and histological subtypes. Front Public Health. 2022 Dec 2;10:1079543.
242. Wang LY et al. Factors Associated with RANTES, EMMPIRIN, MMP2 and MMP9, and the Association of These Biomarkers with Cardiovascular Disease in a Multi-Ethnic Population. J Clin Med. 2022 Dec 8;11(24):7281.
241. Kanoni S et al. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Genome Biol. 2022 Dec 27;23(1):268.
240. Zhong S et al. Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans. J Clin Invest. 2022 Nov 1;132(21):e152961.
239. Feng Z et al. Determinants of Hardcore Smoking in a MULTI-ETHNIC Study of Cigarette Smokers in Singapore. J Psychoactive Drugs. 2022 Nov 14:1-11.
238. Chan et al. Analysis of clinically relevant variants from ancestrally diverse Asian genomes. Nat Commun. 2022 Nov 5;13(1):6694.
237. Yengo L et al. A saturated map of common genetic variants associated with human height. Nature. 2022 Oct;610(7933):704-712.
236. JS Gounot et al. Genome-centric analysis of short and long read metagenomes reveals uncharacterized microbiome diversity in Southeast Asians. Nat Commun. 2022 Oct 13;13(1):6044
235. Wang et al. Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention. Nat Genet. 2022 Sep;54(9):1332-1344.
234. Lee et al. Dietary patterns and predicted 10-year cardiovascular disease risk in a multiethnic Asian population. Nutr Metab Cardiovasc Dis. 2022 Sep;32(9):2093-2104.
233. Ramdas et al. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Am J Hum Genet. 2022 Aug 4;109(8):1366-1387.
232. Betzler et al. Impact of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) GFR Estimating Equations on CKD Prevalence and Classification Among Asians. Front Med (Lausanne). 2022 Jul 14;9:957437.
231. Winkler et al. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Commun Biol. 2022 Jun 13;5(1):580.
230. Voo TC et al. Public acceptability of COVID-19 control measures in Singapore, Hong Kong, and Malaysia: A cross-sectional survey. Int J Infect Dis. 2022 Jul;120:51-58.
229. Seah JYH et al. Circulating Metabolic Biomarkers Are Consistently Associated With Type 2 Diabetes Risk in Asian and European Populations. J Clin Endocrinol Metab. 2022 Jun 16;107(7):e2751-e2761
228. Low A et al. Mutual exclusion of Methanobrevibacter species in the human gut microbiota facilitates directed cultivation of a Candidatus Methanobrevibacter intestini representative. Microbiol Spectr. 2022 Jun 14;e0084922.
227. Edney SM et al. Advancing understanding of dietary and movement behaviours in an Asian population through real-time monitoring: Protocol of the Continuous Observations of Behavioural Risk Factors in Asia study (COBRA). Digit Health, 2022 Jun 30
226. Boey et al. Secondhand smoke in the densely populated urban setting: A cross-sectional survey of exposure, knowledge, attitudes, and respiratory symptoms. Indoor Air. 2022 Jun;32(6):e13069.
225. Petrunoff N et al. Associations of park features with park use and park-based physical activity in an urban environment in Asia: A cross-sectional study. Health & Place, Volume 75, May 2022, 102790
224. Ng PS et al. Characterisation of protein-truncating and missense variants in PALB2 in 15 768 women from Malaysia and Singapore. J Med Genet. 2022.
223. Lu et al. A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study. Eur Heart J. 2022 May 7;43(18):1702-1711.
222. Dorling et al. Breast cancer risks associated with missense variants in breast cancer susceptibility genes. Genome Med. 2022 May 18;14(1):51.
221. Peh JH et al. Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models: implications for risk stratification. BMC Medicine volume 20, Article number: 150 (2022)
220. Park SH et al. Daily park use, physical activity, and psychological stress: A study using smartphone-based ecological momentary assessment amongst a multi-ethnic Asian cohort. Ment Health Phys Act. 2022;22:100440.
219. Lim CGY et al. Replacing dietary carbohydrates and refined grains with different alternatives and risk of cardiovascular diseases in a multi-ethnic Asian population. Am J Clin Nutr. 2022 Mar 4;115(3):854-863.
218. Breast Cancer Association Consortium. Pathology of Tumors Associated with Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes. JAMA Oncol. 2022 Mar 1;8(3):e216744.
217. Park SH et al. Diet and Physical Activity as Determinants of Continuously Measured Glucose Levels in Persons at High Risk of Type 2 Diabetes. Nutrients. 2022 Jan 15;14(2):366.
216. Lim JT et al. Impact of Subsidy on the Use of Personalized Medicine in Breast Cancer. Value Health Reg Issues. 2022 Jan 29;29:108-115.
2021
215. Hindy G et al. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. Am J Hum Genet. 2021 Dec 16:S0002-9297(21)00452-3.
214. Graham SE et al. The power of genetic diversity in genome-wide association studies of lipids. Nature 600, 675–679 (2021).
213. Clapham HE et al. Contrasting SARS-CoV-2 epidemics in Singapore: cohort studies in migrant workers and the general population. Int J Infect Dis. 2021 Dec 2;115:72-78.
212. Betzler BK et al. Association between Body Mass Index and Chronic Kidney Disease in Asian Populations: A Participant-level Meta-Analysis. 2021 Dec;154:46-54.
211. Peo PS et al. Taste of Modern Diets: The Impact of Food Processing on Nutrient Sensing and Dietary Energy Intake. J Nutr . 2021 Oct 12;nxab318.
210. Chen Y et al. Impact of BMI and waist circumference on epigenome-wide DNA methylation and identification of epigenetic biomarkers in blood: an EWAS in multi-ethnic Asian individuals. Clin Epigenet 13, 195 (2021).
209. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021 Sep 11;398(10304):957-980.
208. Goyal S et al. APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups. Lipids Health Dis. 2021 Sep 21;20(1):113.
207. Goh AT et al. Increased oral processing and a slower eating rate increase glycaemic, insulin and satiety responses to a mixed meal tolerance test. Eur J Nutr 2021 Aug;60(5):2719-2733
206. Ding Y et al. Comparative Genomic Analysis of Extended-spectrum β-lactamase and mcr-1 Positive Escherichia coli from Gut Microbiota of Healthy Singaporean. Appl Environ Microbiol. 2021 Aug 4;AEM0048821
205. Chan TK et al. Cancer Screening Knowledge and Behaviour in a Multi-Ethnic Asian Population: the Singapore Community Health Study. Front. Oncol. 12 August 2021
204. Whitton C et al. Longitudinal Associations of Marital, Parenting, and Employment Transitions with Weight Gain in a Multi-Ethnic Asian Population Aged 21 Years and Above. Int. J. Environ. Res. Public Health 2021, 18(15), 8115
203. Petrunoff NA et al. Associations of park access, park use and physical activity in parks with wellbeing in an Asian urban environment: a cross-sectional study. Int J Behav Nutr Phys Act. 2021 Jul 2;18(1):87
202. ven der Eijk et al. Cross-sectional survey of flavored cigarette use among adult smokers in Singapore. Tob Induc Dis. 2021 Jun 3;19:42.
201. JK Goodrich et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nat Commun. 2021 Jun 9;12(1):3505
200. J Chen et al. The trans-ancestral genomic architecture of glycemic traits. Nat Genet. 2021 Jun;53(6):840-860
199. Lim CGY et al. Diet Quality and Lower Refined Grain Consumption are Associated With Less Weight Gain in a Multi-Ethnic Asian Adult Population. J Nutr. 2021 May 12;nxab110
198. Ho PJ et al. Cohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers. PLoS One. 2021 Apr 26;16(4):e0250102.
197. NCD Risk Factor Collaboration (NCD-RisC). Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight. Elife. 2021 Mar 9;10:e60060
196. Seah JYH et al. Dietary Fat and Protein Intake in Relation to Plasma Sphingolipids as Determined by a Large-Scale Lipidomic Analysis. Metabolites. 2021 Feb 8;11(2):93
195. Kassam I et al. Genome-wide identification of cis DNA methylation quantitative trait loci in three Southeast Asian populations. Hum Mol Genet 2021 Feb 6;ddab038
194. Breast Cancer Association Consortium et al. Breast Cancer Risk Genes – Association Analysis in More than 113,000 Women. N Engl J Med. 2021 Feb 4;384(5):428-439
193. Park SH et al. Adaptation and Validation of a Short Acculturation Scale in a Multi-Ethnic Asian Population. Psych 2021, 3(1), 25-38
2020
192. Surendran P et al. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2020 Dec;52(12):1314-1332.
191. Park SH et al. Ethnicity, Neighborhood and Individual Socioeconomic Status, and Obesity: The Singapore Multiethnic Cohort. Obesity (Silver Spring). 2020 Dec;28(12):2405-2413
190. Müller-Riemenschneider F et al. The Association of Different Types of Leisure Time Physical Activities with Cardiometabolic Outcomes in Singapore-Findings from the Multi-Ethnic Cohort Study. Int J Environ Res Public Health. 2020 Dec 3;17(23):9030
189. Vaingankar et al. Sleep duration, sleep quality and physical activity, but not sedentary behaviour, are associated with positive mental health in a multi-ethnic Asian. Int J Environ Res Public Health. 2020 Nov 16;17(22):8489
188. Teo PS et al. Consumption of Foods with Higher Energy Intake Rates is Associated with Greater Energy Intake, Adiposity, and Cardiovascular Risk Factors in Adults. J Nutr. 2020 Nov 26;nxaa344
187. Ying L et al. Development of a serum miRNA panel for detection of early stage non-small cell lung cancer. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25036-25042
186. Teo PS, van Dam RM, Forde CG. Combined Impact of a Faster Self-Reported Eating Rate and Higher Dietary Energy Intake Rate on Energy Intake and Adiposity. Nutrients. 2020 Oct 25;12(11):3264
185. Seow WJ et al. Coffee, Black Tea, and Green Tea Consumption in Relation to Plasma Metabolites in an Asian Population. Mol Nutr Food Res. 2020 Oct 29:e2000527
184. Gunther SH et al. Serum acylcarnitines and amino acids and risk of type 2 diabetes in a multiethnic Asian population. BMJ Open Diabetes Res Care. 2020 Oct;8(1):e001315.
183. Lim JM. et al. Population anxiety and positive behaviour change during the COVID-19 epidemic: Cross-sectional surveys in Singapore, China and Italy. Influenza and Other Respiratory Viruses. 2020 Sep 05.
182. Chai JF et al. Genome-wide association for HbA1c in Malay identified deletion on SLC4A1 that influences HbA1c independent of glycemia. J Clin Endocrinol Metab. 2020 Sep 16:dgaa658.
181. Seah JYH et al. Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis. Metabolomics. 2020 Aug 20;16(9):89.
180. Gunther SH et al. Diet, Physical Activity and Adiposity as Determinants of Circulating Amino Acid Levels in a Multiethnic Asian Population. Nutrients. 2020 Aug 27;12(9):E2603.
179. Ding Y et al. Emergence of Tigecycline- and Eravacycline-resistant Tet(X4)-producing Enterobacteriaceae in the gut microbiota of healthy Singaporeans. J Antimicrob Chemoth. 2020 Aug 27: dkaa372
178. Zheng Y et al. Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. Eur J Epidemiol (2020)
177. Ho WK et al. European polygenic risk score for prediction of breast cancer shows similar performance in Asian women. Nat Commun. 2020 Jul 31;11(1):3833
176. Spracklen CN etal. Identification of Type 2 Diabetes Loci in 433,540 East Asian Individuals. Nature. 2020 Jun;582(7811):240-245.
175. NCD Risk Factor Collaboration (NCD-RisC). Repositioning of the Global Epicentre of Non-Optimal Cholesterol. Nature. 2020 Jun;582(7810):73-77.
174. Jones M et al. Exploring Factors Underlying Ethnic Difference in Age-related Macular Degeneration Prevalence. Ophthalmic Epidemiol. 2020 Jun 8;1-10
173. Fuentes LDL et al. Gene-educational Attainment Interactions in a Multi-Ancestry Genome-Wide Meta-Analysis Identify Novel Blood Pressure Loci. Mol Psychiatry. 2020 May 5.
172. Dou J et al. Using off-target data from whole-exome sequencing to improve genotyping accuracy, association analysis and polygenic risk prediction. Brief Bioinform. 2020 Jun 17:bbaa084.
171. Luo M et al. Cohort profile: the Singapore diabetic cohort study. BMJ Open 2020;10:e036443.
170. Vaingankar et al. Development and validation of the Rapid Positive Mental Health Instrument (R-PMHI) for measuring mental health outcomes in the population. BMC Public Health. 20, 471 (2020)
169. Teo PS et al. Association between self-reported eating rate, energy intake, and cardiovascular risk factors in a multi-ethnic Asian population. Nutrients 2020, 12(4), 1080
168. Zheng FH et al. Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia. Acta Ophthalmol. 2020 Jun 29.
167. Lee JK et al. Social Capital and Health Communication in Singapore: An Examination of the Relationships between Community Participation, Perceived Neighborliness and Health Communication Behaviors. J Health Commun. 00: 1–10, 2020
166. Ding Q et al. Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function. J Hum Genet. 2020 Apr;65(4):411-420.
165. Leong A et al. Association of G6PD variants with hemoglobin A1c and impact on diabetes diagnosis in East Asian individuals. BMJ Open Diabetes Res Care. 2020 Mar;8(1). pii: e001091
164. Chu AHY et al. Accelerometer Profile of Physical Activity and Sedentary Behavior in a Multi-Ethnic Urban Asian Population. Res Q Exerc Sport. 2020 Mar 10:1-8
163. Sumner J et al. Volume and Intensity of Stepping Activity and Cardiometabolic Risk Factors in a Multi-ethnic Asian Population. Int J Environ Res Public Health. 2020 Jan 30;17(3). pii: E863
2019
162. Cheong KW etal. Sun Exposure and Sun Safety Habits Among Adults in Singapore: A Cross-Sectional Study. Ann Acad Med Singapore. 2019 Dec;48(12):412-428.
161. Clark D et al. Associations of autozygosity with a broad range of human phenotypes. Nat Commun. 2019 Oct 31;10(1):4957.
160. Chai JF et al. Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer’s and Parkinson’s diseases. Hum Mol Genet. 2019 Oct 19.
159. Teumer A et al. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun. 2019 Sep 11;10(1):4130
158. Lim CGY and van Dam RM. Attitudes and beliefs regarding food in a multi-ethnic Asian population and their association with socio-demographic variables and healthy eating intentions. Appetite. 2019 Sep 17;144:104461.
157. BIRTH-GENE (BIG) Study Working Group et al. Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. JAMA Netw Open. 2019 Sep 4;2(9):e1910915
156. Wuttke M et al. A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet. 2019 Jun;51(6):957-972
155. Müller AM et al. Associations between psychological factors and accelerometer-measured physical activity in urban Asian adults. Int J Public Health. 2019 Jun;64(5):659-668.
154. Flannick J et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019 Jun;570(7759):71-76
153. Hoong JSY et al. Plasma Sphingolipids and Subclinical Atherosclerosis – Novel Associations Uncovered by a Large-scale Lipidomic Analysis (P18-129-19). Curr Dev Nutr. 2019 Jun 13;3(Suppl 1). pii: nzz039.P18-129-19.
152. de Vries PS et al. Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. Am J Epidemiol. 2019 Jun 1;188(6):1033-1054
151. Chew WS et al. Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence. JCI Insight. 2019 Jun 4;5. pii: 126925.
150. Liew SJ et al. Sociodemographic factors in relation to hypertension prevalence, awareness, treatment and control in a multi-ethnic Asian population: a cross-sectional study. BMJ Open. 2019 May 19;9(5):e025869.
149. Ho VWT et al. Cumulative Effect of Visual Impairment, Multimorbidity, and Frailty on Intrinsic Capacity in Community-Dwelling Older Adults. J Aging Health. 2019 May 8:898264319847818.
148. Sung YJ et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Hum Mol Genet. 2019 Apr 10. pii: ddz070.
147. Bentley AR et al. Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nat Genet. 2019 Apr;51(4):636-648
146. Saw SM et al. Prevention and Management of Myopia and Myopic Pathology. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):488-499
145. Luo M et al. Association of diabetes treatment with long-term glycemic patterns in patients with type 2 diabetes mellitus: A prospective cohort study. Diabetes Metab Res Rev. 2019 Jan 2:e3122.
144. Kilpeläinen TO et al. Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nat Commun. 2019 Jan 22;10(1):376.
2018
143. Takeuchi F et al. Interethnic analyses of blood pressure loci in populations of East Asian and European descent. Nat Commun. 2018 Nov 28;9(1):5052
142. Merchant RA et al. Vitamin D Binding Protein and Vitamin D Levels in Multi-Ethnic Population. J Nutr Health Aging. 2018;22(9):1060-1065.
141. van Zuydam NR et al. A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes. Diabetes. 2018 Jul;67(7):1414-1427
140. Feitosa MF et al. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS One. 2018; 13(6): e0198166.
139. Yap P et al. Prevalence of and risk factors associated with latent tuberculosis in Singapore: a cross-sectional survey. Int J Infect Dis. 2018 May 11. pii: S1201-9712(18)34412-6
138. Whitton C et al. A Healthy Asian A Posteriori Dietary Pattern Correlates with A Priori Dietary Patterns and Is Associated with Cardiovascular Disease Risk Factors in a Multiethnic Asian Population. J Nutr. 2018 Apr 1;148(4):616-623.
137. Sumner J et al. Stepping volume and intensity patterns in a multi-ethnic urban Asian population. BMC Public Health. 2018 Apr 23;18(1):539.
136. Khaing EE et al. Epicardial and visceral adipose tissue in relation to subclinical atherosclerosis in a Chinese population. PLoS One. 2018 Apr 25;13(4):e0196328
135. Hou Y et al. Adequacy of public health communications on H7N9 and MERS in Singapore: insights from a community based cross-sectional study. BMC Public Health. Apr 2018; 18:436
134. Chu AHY et al. Self-reported domain-specific and accelerometer-based physical activity and sedentary behaviour in relation to psychological distress among an urban Asian population. Int J Behav Nutr Phys Act. 2018; 15:36
133. Vaingankar J et al. Psychometric properties and population norms of the Positive Mental Health instrument in a representative multi-ethnic Asian population. BMC Med Res Methodol. (2018) 18:29
132. Tan KHX et al. Cohort Profile: The Singapore Multi-Ethnic Cohort (MEC) study. Int J Epidemiol. 2018 Feb 13
131. Sung YJ et al. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet. 2018 Mar 1;102(3):375-400.
130. Chang X et al. Gene-diet interaction effects on BMI levels in the Singapore Chinese population. Nutr J. 2018 Feb 24;17(1):31.
2017
129. Uijtdewilligen et al. Correlates of occupational, leisure and total sitting time in working adults: results from the Singapore multi-ethnic cohort. Int J Behav Nutr Phys Act. 2017; 14: 169
128. Tan A et al. Validation of NoSAS score for screening of sleep-disordered breathing in a multiethnic Asian population. Sleep Breath. 2017 Dec;21(4):1033-1038.
127. Han Y et al. Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia. Sci Rep. 2017 Dec 20;7(1):17921.
126. Jiang L et al. Comparison of self-reported contacts between hospital-based healthcare workers and working adults from the general population and its implications for infectious disease transmission. J Hosp Infect. 2017 Oct 30. pii: S0195-6701(17)30587-X.
125. Saw WY et al. Establishing multiple omics baselines for three Southeast Asian ethnic groups in the Singapore Integrative Omics Cohort. Nat Comm. 2017 Sep 21; 8:653
124. Goh EH et al. Epidemiology and relative severity of influenza subtypes in Singapore in the post-pandemic period from 2009 to 2010. Clin Infect Dis. 2017 Sep 23.
123. Sia CH et al. Awareness and knowledge of obstructive sleep apnea in the general population. Sleep Med. Aug 2017; 36:10-17
122. Merchant R et al. Singapore Healthy Older People Everyday (HOPE) Study: Prevalence of Frailty and Associated Factors in Older Adults. J Am Med Dir Assoc. 2017 Jun 13
121. Luo Ma et al. Longitudinal trends in HbA1c and associations with comorbidity and all-cause mortality in Asian patients with type 2 diabetes: A cohort study. Diabetes Res Clin Pract. 2017 Aug 24;133:69-77.
120. Spracklen CN et al. Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. Hum Mol Genet. 2017 May 1;26(9):1770-1784
119. Han MR et al. Evaluating genetic variants associated with breast cancer risk in high and moderate-penetrance genes in Asians. Carcinogenesis. 2017 May 1;38(5):511-518
118. Li C et al. Genome-Wide Association Study Meta-Analysis of Long-Term Average Blood Pressure in East Asians. Circ Cardiovasc Genet. 2017 Apr;10(2):e001527.
117. Shimelis H et al. BRCA2 hypomorphic missense variants confer moderate risks of breast cancer. Cancer Res. 2017 Mar 10.
116. Jiang L et al. Detection of viral respiratory pathogens in mild and severe acute respiratory infections in Singapore. Sci Rep. 2017 Feb 20;7:42963.
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2015
90. Koh HW et al. The Pittsburgh Sleep Quality Index in a multi-ethnic Asian population contains a three-factor structure. Sleep Breath. 2015 Dec;19(4):1147-54
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82. Darabi H et al. Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. Am J Hum Genet. 2015 Jul 2;97(1):22-34.
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2014
71. Qi Q et al. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet. 2014 Dec 20;23(25):6961-72.
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57. Zuñiga YL et al. Rice and noodle consumption is associated with insulin resistance and hyperglycaemia in an Asian population. Br J Nutr. 2014 Mar 28;111(6):1118-28.
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2013
54. Gao H et al. Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations. Diabetes. 2013 Dec;62(12):4277-83.
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2012
36. Lim XL et al. KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes. Diabetologia. 2012 Sep;55(9):2402-6.
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2011
27. Fan Q et al. Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. PLoS Genet. 2011 Dec;7(12):e1002402.
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2010
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2009
8. Teo YY et al. Singapore Genome Variation Project: a haplotype map of three Southeast Asian populations. Genome Res. 2009 Nov;19(11):2154-62.
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2008
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2007
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2006
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