2023
- Assessing the external validity of machine learning-based detection of glaucoma Li C, Chua J, Schwarzhans F, Husain R, Girard MJA, Majithia S, Tham YC, Cheng CY, Aung T, Fischer G, Vass C, Bujor I, Kwoh CK, Popa-Cherecheanu A, Schmetterer L, Wong D. Sci Rep, 2023 Jan 11; 13(1): 558.
- Rare variant analyses across multiethnic cohorts identify novel genes for refractive error Musolf AM, Haarman AEG, Luben RN, Ong JS, Patasova K, Trapero RH, Marsh J, Jain I, Jain R, Wang PZ, Lewis DD, Tedja MS, Iglesias AI, Li H, Cowan CS, Consortium for Refractive Error and Myopia (CREAM), Biino G, Klein AP, Duggal P, Mackey DA, Hayward C, Haller T, Metspalu A, Wedenoja J, Parssinen O, Cheng CY, Saw SM, Stambolian D, Hysi PG, Khawaja AP, Vitart V, Hammond CJ, van Duijn CM, Verhoeven VJM, Klaver CCW, Bailey-Wilson JE. Commun Biol, 2023 Jan 3; 6(1): 6.
- Validation of a deep-learning-based retinal biomarker (Reti-CVD) in the prediction of cardiovascular disease: data from UK Biobank Tseng R, Rim TH, Shantsila E, Yi JK, Park S, Kim SS, Lee CJ, Thakur S, Nusinovici S, Peng Q, Kim H, Lee G, Yu M, Tham YC, Bakhai A, Leeson P, Lip GYH, Wong TY, Cheng CY. BMC Med, 2023 Jan 24; 21(1): 28.
- Genetic Variability of Complement Factor H Has Ethnicity-Specific Associations With Choroidal Thickness Fenner BJ, Li H, Gan ATL, Song YS, Tham YC, Jonas JB, Wang YX, Cheng CY, Wong TY, Teo KYC, Tan ACS, Fan Q, Cheung CMG. Invest Ophthalmol Vis Sci, 2023 Feb 1; 64(2): 10.
- From 2 dimensions to 3rd dimension: Quantitative prediction of anterior chamber depth from anterior segment photographs via deep-learning Soh ZD, Jiang Y, SS SOG, Zhou M, Nongiur M, Majithia S, Tham YC, Rim TH, Qian C, Koh V, Aung T, Wong TY, Xu X, Liu Y, Cheng CY. PLOS Digit Health, 2023 Feb; 2(2): e0000193.
- Pattern and Characteristics of Drusen Subtypes in Chinese and Indian Populations in Singapore Takahashi K, Song Y, Cheong KX, Fenner BJ, Teo KYC, Chee ML, Li H, Tham YC, Cheung CMG, Cheng CY, Wong TY, Yanagi Y, Tan ACS. Retina, 2023 Feb 1; 43(2): 303-312.
- Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Rayner NW, Bocher O, Ana Luiza de SVA, Sonehara K, Namba S, Lee SSK, Preuss MH, Petty LE, Schroeder P, Vanderwerff B, Kals M, Bragg F, Lin K, Guo X, Zhang W, Yao J, Kim YJ, Graff M, Takeuchi F, Nano J, Lamri A, Nakatochi M, Moon S, Scott RA, Cook JP, Lee JJ, Pan I, Taliun D, Parra EJ, Chai JF, Bielak LF, Tabara Y, Hai Y, Thorleifsson G, Grarup N, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Kwak SH, Long J, Sun M, Tong L, Chen WM, Nongmaithem SS, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Prins BP, Nicolas A, Yanek LR, Chen G, Brody JA, Kabagambe E, An P, Xiang AH, Choi HS, Cade BE, Tan J, Alaine Broadaway K, Williamson A, Kamali Z, Cui J, Adair LS, Adeyemo A, Aguilar-Salinas CA, Ahluwalia TS, Anand SS, Bertoni A, Bork-Jensen J, Brandslund I, Buchanan TA, Burant CF, Butterworth AS, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chuang LM, Cushman M, Danesh J, Das SK, Janaka de Silva H, Dedoussis G, Dimitrov L, Doumatey AP, Du S, Duan Q, Eckardt KU, Emery LS, Evans DS, Evans MK, Fischer K, Floyd JS, Ford I, Franco OH, Frayling TM, Freedman BI, Genter P, Gerstein HC, Giedraitis V, Gonzalez-Villalpando C, Gonzalez-Villalpando ME, Gordon-Larsen P, Gross M, Guare LA, Hackinger S, Han S, Hattersley AT, Herder C, Horikoshi M, Howard AG, Hsueh W, Huang M, Huang W, Hung YJ, Hwang MY, Hwu CM, Ichihara S, Ikram MA, Ingelsson M, Islam MT, Isono M, Jang HM, Jasmine F, Jiang G, Jonas JB, Jorgensen T, Kandeel FR, Kasturiratne A, Katsuya T, Kaur V, Kawaguchi T, Keaton JM, Kho AN, Khor CC, Kibriya MG, Kim DH, Kronenberg F, Kuusisto J, Lall K, Lange LA, Lee KM, Lee MS, Lee NR, Leong A, Li L, Li Y, Li-Gao R, Lithgart S, Lindgren CM, Linneberg A, Liu CT, Liu J, Locke AE, Louie T, Luan J, Luk AO, Luo X, Lv J, Lynch JA, Lyssenko V, Maeda S, Mamakou V, Mansuri SR, Matsuda K, Meitinger T, Metspalu A, Mo H, Morris AD, Nadler JL, Nalls MA, Nayak U, Ntalla I, Okada Y, Orozco L, Patel SR, Patil S, Pei P, Pereira MA, Peters A, Pirie FJ, Polikowsky HG, Porneala B, Prasad G, Rasmussen-Torvik LJ, Reiner AP, Roden M, Rohde R, Roll K, Sabanayagam C, Sandow K, Sankareswaran A, Sattar N, Schonherr S, Shahriar M, Shen B, Shi J, Shin DM, Shojima N, Smith JA, So WY, Stancakova A, Steinthorsdottir V, Stilp AM, Strauch K, Taylor KD, Thorand B, Thorsteinsdottir U, Tomlinson B, Tran TC, Tsai FJ, Tuomilehto J, Tusie-Luna T, Udler MS, Valladares-Salgado A, van Dam RM, van Klinken JB, Varma R, Wacher-Rodarte N, Wheeler E, Wickremasinghe AR, van Dijk KW, Witte DR, Yajnik CS, Yamamoto K, Yamamoto K, Yoon K, Yu C, Yuan JM, Yusuf S, Zawistowski M, Zhang L, Zheng W, Va Million Veteran Program Amed Grifin Diabetes Initiative Japan, Project B.J., BioBank P.M., Center R.G., Consortium E, International Consortium for Blood Pressure, Meta-Analyses of Glucose Insulin-Related Traits Consortium, Raffel LJ, Igase M, Ipp E, Redline S, Cho YS, Lind L, Province MA, Fornage M, Hanis CL, Ingelsson E, Zonderman AB, Psaty BM, Wang YX, Rotimi CN, Becker DM, Matsuda F, Liu Y, Yokota M, Kardia SLR, Peyser PA, Pankow JS, Engert JC, Bonnefond A, Froguel P, Wilson JG, Sheu WHH, Wu JY, Geoffrey Hayes M, Ma RCW, Wong TY, Mook-Kanamori DO, Tuomi T, Chandak GR, Collins FS, Bharadwaj D, Pare G, Sale MM, Ahsan H, Motala AA, Shu XO, Park KS, Jukema JW, Cruz M, Chen YI, Rich SS, McKean-Cowdin R, Grallert H, Cheng CY, Ghanbari M, Tai ES, Dupuis J, Kato N, Laakso M, Kottgen A, Koh WP, Bowden DW, Palmer CNA, Kooner JS, Kooperberg C, Liu S, North KE, Saleheen D, Hansen T, Pedersen O, Wareham NJ, Lee J, Kim BJ, Millwood IY, Walters RG, Stefansson K, Goodarzi MO, Mohlke KL, Langenberg C, Haiman CA, Loos RJF, Florez JC, Rader DJ, Ritchie MD, Zollner S, Magi R, Denny JC, Yamauchi T, Kadowaki T, Chambers JC, Ng MCY, Sim X, Below JE, Tsao PS, Chang KM, McCarthy MI, Meigs JB, Mahajan A, Spracklen CN, Mercader JM, Boehnke M, Rotter JI, Vujkovic M, Voight BF, Morris AP, Zeggini E. medRxiv, 2023 Mar 31.
- Relationship between vision impairment and employment Chai YX, Gan ATL, Fenwick EK, Sui AY, Tan BKJ, Quek DQY, Qian C, Wong TY, Cheng CY, Lamoureux EL, Man REK. Br J Ophthalmol, 2023 Mar; 107(3): 361-366.
- Six-year incidence of age-related macular degeneration and correlation to OCT-derived drusen volume measurements in a Chinese population Tan AC, Chee ML, Fenner BJ, Mitchell P, Tham YC, Rim T, Teo K, Sim SS, Cheng CY, Wong TY, Chakravarthy U, Cheung CMG. Br J Ophthalmol, 2023 Mar; 107(3): 392-398.
- Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease Duperron MG, Knol MJ, Le Grand Q, Evans TE, Mishra A, Tsuchida A, Roshchupkin G, Konuma T, Tregouet DA, Romero JR, Frenzel S, Luciano M, Hofer E, Bourgey M, Dueker ND, Delgado P, Hilal S, Tankard RM, Dubost F, Shin J, Saba Y, Armstrong NJ, Bordes C, Bastin ME, Beiser A, Brodaty H, Bulow R, Carrera C, Chen C, Cheng CY, Deary IJ, Gampawar PG, Himali JJ, Jiang J, Kawaguchi T, Li S, Macalli M, Marquis P, Morris Z, Munoz Maniega S, Miyamoto S, Okawa M, Paradise M, Parva P, Rundek T, Sargurupremraj M, Schilling S, Setoh K, Soukarieh O, Tabara Y, Teumer A, Thalamuthu A, Trollor JN, Valdes Hernandez MC, Vernooij MW, Volker U, Wittfeld K, Wong TY, Wright MJ, Zhang J, Zhao W, Zhu YC, Schmidt H, Sachdev PS, Wen W, Yoshida K, Joutel A, Satizabal CL, Sacco RL, Bourque G, Charge Consortium, Lathrop M, Paus T, Fernandez-Cadenas I, Yang Q, Mazoyer B, Boutinaud P, Okada Y, Grabe HJ, Mather KA, Schmidt R, Joliot M, Ikram MA, Matsuda F, Tzourio C, Wardlaw JM, Seshadri S, Adams HHH, Debette S. Nat Med, 2023 Apr; 29(4): 950-962.
- Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study Mark PB, Carrero JJ, Matsushita K, Sang Y, Ballew SH, Grams ME, Coresh J, Surapaneni A, Brunskill NJ, Chalmers J, Chan L, Chang AR, Chinnadurai R, Chodick G, Cirillo M, de Zeeuw D, Evans M, Garg AX, Gutierrez OM, Heerspink HJL, Heine GH, Herrington WG, Ishigami J, Kronenberg F, Lee JY, Levin A, Major RW, Marks A, Nadkarni GN, Naimark DMJ, Nowak C, Rahman M, Sabanayagam C, Sarnak M, Sawhney S, Schneider MP, Shalev V, Shin JI, Siddiqui MK, Stempniewicz N, Sumida K, Valdivielso JM, van den Brand J, Yee-Moon Wang A, Wheeler DC, Zhang L, Visseren FLJ, Stengel B. Eur Heart J, 2023 Apr 1; 44(13): 1157-1166.
- A five-safes approach to a secure and scalable genomics data repository Shih CC, Chen J, Lee AS, Bertin N, Hebrard M, Khor CC, Li Z, Juan Tan JH, Meah WY, Peh SQ, Mok SQ, Sim KS, Liu J, Wang L, Wong E, Li J, Tin A, Cheng CY, Heng CK, Yuan JM, Koh WP, Saw SM, Friedlander Y, Sim X, Chai JF, Chong YS, Davila S, Goh LL, Lee ES, Wong TY, Karnani N, Leong KP, Yeo KK, Chambers JC, Lim SC, Goh RSM, Tan P, Dorajoo R. iScience, 2023 Apr 21; 26(4): 106546.
- Mendelian Randomization Implicates Bidirectional Association between Myopia and Primary Open-Angle Glaucoma or Intraocular Pressure Chong RS, Li H, Cheong AJY, Fan Q, Koh V, Raghavan L, Nongpiur ME, Cheng CY. Ophthalmology, 2023 Apr; 130(4): 394-403.
- Cardiovascular disease risk assessment using a deep-learning-based retinal biomarker: a comparison with existing risk scores Yi JK, Rim TH, Park S, Kim SS, Kim HC, Lee CJ, Kim H, Lee G, Lim JSG, Tan YY, Yu M, Tham YC, Bakhai A, Shantsila E, Leeson P, Lip GYH, Chin CWL, Cheng CY. Eur Heart J Digit Health, 2023 May; 4(3): 236-244.
- A multiethnic genome-wide analysis of 19,420 individuals identifies novel loci associated with axial length and shared genetic influences with refractive error and myopia Jiang C, Melles RB, Yin J, Fan Q, Guo X, Cheng CY, He M, Mackey DA, Guggenheim JA, Klaver C, Consortium for Refractive Error and Myopia (CREAM), Nair KS, Jorgenson E, Choquet H. Front Genet, 2023; 14: 1113058.
2022
- Identification of novel loci influencing refractive error in East Asian populations using an extreme phenotype design Han X, Liu T, Ding X, Liu J, Lin X, Wang D, Riaz M, Baird PN, Xie Z, Cheng Y, Li Y, Mori Y, Miyake M, Li H, Cheng CY, Zeng C, Ohno-Matsui K, Zhou X, Liu F, He M. J Genet Genomics, 2022 Jan; 49(1): 54-62.
- Prevalence of Polypoidal Choroidal Vasculopathy Using Non-indocyanine green angiography-based Criteria Fenner BJ, Teo KYC, Tham YC, Chakravarthy U, Cheung CMG. Ophthalmol Retina, 2022 Feb; 6(2): 179-181.
- Machine learning to determine relative contribution of modifiable and non-modifiable risk factors of major eye diseases Nusinovici S, Zhang L, Chai X, Zhou L, Tham YC, Vasseneix C, Majithia S, Sabanayagam C, Wong TY, Cheng CY. Br J Ophthalmol, 2022 Feb; 106(2): 267-274.
- Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies Sun Q, Graff M, Rowland B, Wen J, Huang L, Miller-Fleming TW, Haessler J, Preuss MH, Chai JF, Lee MP, Avery CL, Cheng CY, Franceschini N, Sim X, Cox NJ, Kooperberg C, North KE, Li Y, Raffield LM. J Hum Genet, 2022 Feb; 67(2): 87-93.
- Three-dimensional modelling of the choroidal angioarchitecture in a multi-ethnic Asian population Cheong KX, Teo KYC, Tham YC, Sim R, Majithia S, Lee JM, Tan ACS, Cheng CY, Cheung CMG, Agrawal R. Sci Rep, 2022 Mar 9; 12(1): 3831.
- Normative profiles of neuroretinal rim area in a multiethnic Asian population: the Singapore Epidemiology of Eye Diseases study Lim ZW, Chee ML, Lim SH, Thakur S, Majithia S, Soh ZD, Teo ZL, Rim TH, Sabanayagam C, Tham YC, Cheng CY. Br J Ophthalmol, 2022 Mar; 106(3): 381-387.
- High-Density Lipoprotein 3 Cholesterol and Primary Open-Angle Glaucoma: Metabolomics and Mendelian Randomization Analyses Nusinovici S, Li H, Thakur S, Baskaran M, Tham YC, Zhou L, Sabanayagam C, Aung T, Silver D, Fan Q, Wong TY, Crowston J, Cheng CY. Ophthalmology, 2022 Mar; 129(3): 285-294.
- Detecting visually significant cataract using retinal photograph-based deep learning Tham YC, Goh JHL, Anees A, Lei X, Rim TH, Chee ML, Wang YX, Jonas JB, Thakur S, Teo ZL, Cheung N, Hamzah H, Tan GSW, Husain R, Sabanayagam C, Wang JJ, Chen Q, Lu Z, Keenan TD, Chew EY, Tan AG, Mitchell P, Goh RSM, Xu X, Liu Y, Wong TY, Cheng CY. Nat Aging, 2022 Mar; 2(3): 264-271.
- Cerebral Microbleeds, Cerebral Amyloid Angiopathy, and Their Relationships to Quantitative Markers of Neurodegeneration Beaman C, Kozii K, Hilal S, Liu M, Spagnolo-Allende AJ, Polanco-Serra G, Chen C, Cheng CY, Zambrano D, Arikan B, Del Brutto VJ, Wright C, Flowers XE, Leskinen SP, Rundek T, Mitchell A, Vonsattel JP, Cortes E, Teich AF, Sacco RL, Elkind MSV, Roh D, Gutierrez J, Alzheimer’s Disease Neuroimaging Initiative. Neurology, 2022 Apr 19; 98(16): e1605-e1616.
- Identification of genetic effects underlying type 2 diabetes in South Asian and European populations Loh M, Zhang W, Ng HK, Schmid K, Lamri A, Tong L, Ahmad M, Lee JJ, Ng MCY, Petty LE, Spracklen CN, Takeuchi F, Islam MT, Jasmine F, Kasturiratne A, Kibriya M, Mohlke KL, Pare G, Prasad G, Shahriar M, Chee ML, de Silva HJ, Engert JC, Gerstein HC, Mani KR, Sabanayagam C, Vujkovic M, Wickremasinghe AR, Wong TY, Yajnik CS, Yusuf S, Ahsan H, Bharadwaj D, Anand SS, Below JE, Boehnke M, Bowden DW, Chandak GR, Cheng CY, Kato N, Mahajan A, Sim X, McCarthy MI, Morris AP, Kooner JS, Saleheen D, Chambers JC. Commun Biol, 2022 Apr 7; 5(1): 329.
- Peripapillary sclera exhibits a v-shaped configuration that is more pronounced in glaucoma eyes Wang X, Tun TA, Nongpiur ME, Htoon HM, Tham YC, Strouthidis NG, Aung T, Cheng CY, Girard MJ. Br J Ophthalmol, 2022 Apr; 106(4): 491-496.
- Predictors of myopic macular degeneration in a 12-year longitudinal study of Singapore adults with myopia Foo LL, Xu L, Sabanayagam C, Htoon HM, Ang M, Zhang J, Ohno-Matsui K, Cheng CY, Hoang QV, Tan CS, Saw SM, Wong CW. Br J Ophthalmol, 2022 May 9.
- Different impact of early and late stages irreversible eye diseases on vision-specific quality of life domains Gupta P, Fenwick EK, Man REK, Gan ATL, Sabanayagam C, Quek D, Qian C, Cheung CMG, Cheng CY, Lamoureux EL. Sci Rep, 2022 May 19; 12(1): 8465.
- DeepLensNet: Deep Learning Automated Diagnosis and Quantitative Classification of Cataract Type and Severity Keenan TDL, Chen Q, Agron E, Tham YC, Goh JHL, Lei X, Ng YP, Liu Y, Xu X, Cheng CY, Bikbov MM, Jonas JB, Bhandari S, Broadhead GK, Colyer MH, Corsini J, Cousineau-Krieger C, Gensheimer W, Grasic D, Lamba T, Magone MT, Maiberger M, Oshinsky A, Purt B, Shin SY, Thavikulwat AT, Lu Z, Chew EY, Areds Deep Learning Research Group. Ophthalmology, 2022 May; 129(5): 571-584.
- A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study Lu X, Liu Z, Cui Q, Liu F, Li J, Niu X, Shen C, Hu D, Huang K, Chen J, Xing X, Zhao Y, Lu F, Liu X, Cao J, Chen S, Ma H, Yu L, Wu X, Wu X, Li Y, Zhang H, Mo X, Zhao L, Huang J, Wang L, Wen W, Shu XO, Takeuchi F, Koh WP, Tai ES, Cheng CY, Wong TY, Chang X, Chan MY, Gao W, Zheng H, Chen K, Chen J, He J, Tang CS, Lam KSL, Tse HF, Cheung CYY, Takahashi A, Kubo M, Kato N, Terao C, Kamatani Y, Sham PC, Heng CK, Hu Z, Chen YE, Wu T, Shen H, Willer CJ, Gu D. Eur Heart J, 2022 May 7; 43(18): 1702-1711.
- Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rueger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, Robertson NR, Rayner NW, Loh M, Kim BJ, Chiou J, Miguel-Escalada I, Della Briotta Parolo P, Lin K, Bragg F, Preuss MH, Takeuchi F, Nano J, Guo X, Lamri A, Nakatochi M, Scott RA, Lee JJ, Huerta-Chagoya A, Graff M, Chai JF, Parra EJ, Yao J, Bielak LF, Tabara Y, Hai Y, Steinthorsdottir V, Cook JP, Kals M, Grarup N, Schmidt EM, Pan I, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Long J, Sun M, Tong L, Chen WM, Ahmad M, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Lecoeur C, Prins BP, Nicolas A, Yanek LR, Chen G, Jensen RA, Tajuddin S, Kabagambe EK, An P, Xiang AH, Choi HS, Cade BE, Tan J, Flanagan J, Abaitua F, Adair LS, Adeyemo A, Aguilar-Salinas CA, Akiyama M, Anand SS, Bertoni A, Bian Z, Bork-Jensen J, Brandslund I, Brody JA, Brummett CM, Buchanan TA, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chuang LM, Cushman M, Das SK, de Silva HJ, Dedoussis G, Dimitrov L, Doumatey AP, Du S, Duan Q, Eckardt KU, Emery LS, Evans DS, Evans MK, Fischer K, Floyd JS, Ford I, Fornage M, Franco OH, Frayling TM, Freedman BI, Fuchsberger C, Genter P, Gerstein HC, Giedraitis V, Gonzalez-Villalpando C, Gonzalez-Villalpando ME, Goodarzi MO, Gordon-Larsen P, Gorkin D, Gross M, Guo Y, Hackinger S, Han S, Hattersley AT, Herder C, Howard AG, Hsueh W, Huang M, Huang W, Hung YJ, Hwang MY, Hwu CM, Ichihara S, Ikram MA, Ingelsson M, Islam MT, Isono M, Jang HM, Jasmine F, Jiang G, Jonas JB, Jorgensen ME, Jorgensen T, Kamatani Y, Kandeel FR, Kasturiratne A, Katsuya T, Kaur V, Kawaguchi T, Keaton JM, Kho AN, Khor CC, Kibriya MG, Kim DH, Kohara K, Kriebel J, Kronenberg F, Kuusisto J, Lall K, Lange LA, Lee MS, Lee NR, Leong A, Li L, Li Y, Li-Gao R, Ligthart S, Lindgren CM, Linneberg A, Liu CT, Liu J, Locke AE, Louie T, Luan J, Luk AO, Luo X, Lv J, Lyssenko V, Mamakou V, Mani KR, Meitinger T, Metspalu A, Morris AD, Nadkarni GN, Nadler JL, Nalls MA, Nayak U, Nongmaithem SS, Ntalla I, Okada Y, Orozco L, Patel SR, Pereira MA, Peters A, Pirie FJ, Porneala B, Prasad G, Preissl S, Rasmussen-Torvik LJ, Reiner AP, Roden M, Rohde R, Roll K, Sabanayagam C, Sander M, Sandow K, Sattar N, Schonherr S, Schurmann C, Shahriar M, Shi J, Shin DM, Shriner D, Smith JA, So WY, Stancakova A, Stilp AM, Strauch K, Suzuki K, Takahashi A, Taylor KD, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tomlinson B, Torres JM, Tsai FJ, Tuomilehto J, Tusie-Luna T, Udler MS, Valladares-Salgado A, van Dam RM, van Klinken JB, Varma R, Vujkovic M, Wacher-Rodarte N, Wheeler E, Whitsel EA, Wickremasinghe AR, van Dijk KW, Witte DR, Yajnik CS, Yamamoto K, Yamauchi T, Yengo L, Yoon K, Yu C, Yuan JM, Yusuf S, Zhang L, Zheng W, FinnGen e Merge Consortium, Raffel LJ, Igase M, Ipp E, Redline S, Cho YS, Lind L, Province MA, Hanis CL, Peyser PA, Ingelsson E, Zonderman AB, Psaty BM, Wang YX, Rotimi CN, Becker DM, Matsuda F, Liu Y, Zeggini E, Yokota M, Rich SS, Kooperberg C, Pankow JS, Engert JC, Chen YI, Froguel P, Wilson JG, Sheu WHH, Kardia SLR, Wu JY, Hayes MG, Ma RCW, Wong TY, Groop L, Mook-Kanamori DO, Chandak GR, Collins FS, Bharadwaj D, Pare G, Sale MM, Ahsan H, Motala AA, Shu XO, Park KS, Jukema JW, Cruz M, McKean-Cowdin R, Grallert H, Cheng CY, Bottinger EP, Dehghan A, Tai ES, Dupuis J, Kato N, Laakso M, Kottgen A, Koh WP, Palmer CNA, Liu S, Abecasis G, Kooner JS, Loos RJF, North KE, Haiman CA, Florez JC, Saleheen D, Hansen T, Pedersen O, Magi R, Langenberg C, Wareham NJ, Maeda S, Kadowaki T, Lee J, Millwood IY, Walters RG, Stefansson K, Myers SR, Ferrer J, Gaulton KJ, Meigs JB, Mohlke KL, Gloyn AL, Bowden DW, Below JE, Chambers JC, Sim X, Boehnke M, Rotter JI, McCarthy MI, Morris AP. Nat Genet, 2022 May; 54(5): 560-572.
- Retinal Nerve Fiber Layer Thickness and Rim Area Profiles in Asians: Pooled Analysis from the Asian Eye Epidemiology Consortium Majithia S, Tham YC, Chong CCY, Yu M, Cheung CY, Bikbov MM, Kazakbaeva GM, Wang N, Hao J, Cao K, Wang YX, Sasaki M, Ito Y, Wong IY, Cheuk-Hung Chan J, Khanna RC, Marmamula S, Nakano E, Mori Y, Aung T, Wong TY, Jonas JB, Miyake M, Cheng CY, of the Asian Eye Epidemiology Consortium. Ophthalmology, 2022 May; 129(5): 552-561.
- Machine learning identifying peripheral circulating metabolites associated with intraocular pressure alterations Qian C, Nusinovici S, Thakur S, Soh ZD, Majithia S, Chee ML, Zhong H, Tham YC, Sabanayagam C, Hysi PG, Cheng CY.Br J Ophthalmol, 2022 May 25.
- The longitudinal association between cognitive impairment and incident visual impairment in a multiethnic Asian population: a prospective cohort study Vu TA, Gupta P, Leow FZY, Fenwick EK, Man REK, Tham YC, Xu X, Quek DQY, Qian C, Sabanayagam C, Chen CLH, Wong TY, Cheng CY, Lamoureux EL. Age Ageing, 2022 May 1; 51(5).
- Multivariate Normative Comparison, a Novel Method for Improved Use of Retinal Nerve Fiber Layer Thickness to Detect Early Glaucoma Chua J, Schwarzhans F, Wong D, Li C, Husain R, Crowston JG, Perera SA, Sng CCA, Nongpiur ME, Majithia S, Tham YC, Thakur S, Da Soh Z, Cheng CY, Aung T, Fischer G, Vass C, Schmetterer L. Ophthalmol Glaucoma, 2022 May-Jun; 5(3): 359-368.
- Six-year incidence and systemic associations of retinopathy in a multi-ethnic Asian population without diabetes Gupta P, Lamoureux EL, Sabanayagam C, Tham YC, Tan G, Cheng CY, Wong TY, Cheung N. Br J Ophthalmol, 2022 Jun; 106(6): 845-851.
- Circulating Metabolic Biomarkers Are Consistently Associated With Type 2 Diabetes Risk in Asian and European Populations Seah JYH, Hong Y, Cichonska A, Sabanayagam C, Nusinovici S, Wong TY, Cheng CY, Jousilahti P, Lundqvist A, Perola M, Salomaa V, Tai ES, Wurtz P, van Dam RM, Sim X. J Clin Endocrinol Metab, 2022 Jun 16; 107(7): e2751-e2761.
- Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals Winkler TW, Rasheed H, Teumer A, Gorski M, Rowan BX, Stanzick KJ, Thomas LF, Tin A, Hoppmann A, Chu AY, Tayo B, Thio CHL, Cusi D, Chai JF, Sieber KB, Horn K, Li M, Scholz M, Cocca M, Wuttke M, van der Most PJ, Yang Q, Ghasemi S, Nutile T, Li Y, Pontali G, Gunther F, Dehghan A, Correa A, Parsa A, Feresin A, de Vries APJ, Zonderman AB, Smith AV, Oldehinkel AJ, De Grandi A, Rosenkranz AR, Franke A, Teren A, Metspalu A, Hicks AA, Morris AP, Tonjes A, Morgan A, Podgornaia AI, Peters A, Korner A, Mahajan A, Campbell A, Freedman BI, Spedicati B, Ponte B, Schottker B, Brumpton B, Banas B, Kramer BK, Jung B, Asvold BO, Smith BH, Ning B, Penninx B, Vanderwerff BR, Psaty BM, Kammerer CM, Langefeld CD, Hayward C, Spracklen CN, Robinson-Cohen C, Hartman CA, Lindgren CM, Wang C, Sabanayagam C, Heng CK, Lanzani C, Khor CC, Cheng CY, Fuchsberger C, Gieger C, Shaffer CM, Schulz CA, Willer CJ, Chasman DI, Gudbjartsson DF, Ruggiero D, Toniolo D, Czamara D, Porteous DJ, Waterworth DM, Mascalzoni D, Mook-Kanamori DO, Reilly DF, Daw EW, Hofer E, Boerwinkle E, Salvi E, Bottinger EP, Tai ES, Catamo E, Rizzi F, Guo F, Rivadeneira F, Guilianini F, Sveinbjornsson G, Ehret G, Waeber G, Biino G, Girotto G, Pistis G, Nadkarni GN, Delgado GE, Montgomery GW, Snieder H, Campbell H, White HD, Gao H, Stringham HM, Schmidt H, Li H, Brenner H, Holm H, Kirsten H, Kramer H, Rudan I, Nolte IM, Tzoulaki I, Olafsson I, Martins J, Cook JP, Wilson JF, Halbritter J, Felix JF, Divers J, Kooner JS, Lee JJ, O’Connell J, Rotter JI, Liu J, Xu J, Thiery J, Arnlov J, Kuusisto J, Jakobsdottir J, Tremblay J, Chambers JC, Whitfield JB, Gaziano JM, Marten J, Coresh J, Jonas JB, Mychaleckyj JC, Christensen K, Eckardt KU, Mohlke KL, Endlich K, Dittrich K, Ryan KA, Rice KM, Taylor KD, Ho K, Nikus K, Matsuda K, Strauch K, Miliku K, Hveem K, Lind L, Wallentin L, Yerges-Armstrong LM, Raffield LM, Phillips LS, Launer LJ, Lyytikainen LP, Lange LA, Citterio L, Klaric L, Ikram MA, Ising M, Kleber ME, Francescatto M, Concas MP, Ciullo M, Piratsu M, Orho-Melander M, Laakso M, Loeffler M, Perola M, de Borst MH, Gogele M, Bianca M, Lukas MA, Feitosa MF, Biggs ML, Wojczynski MK, Kavousi M, Kanai M, Akiyama M, Yasuda M, Nauck M, Waldenberger M, Chee ML, Chee ML, Boehnke M, Preuss MH, Stumvoll M, Province MA, Evans MK, O’Donoghue ML, Kubo M, Kahonen M, Kastarinen M, Nalls MA, Kuokkanen M, Ghanbari M, Bochud M, Josyula NS, Martin NG, Tan NYQ, Palmer ND, Pirastu N, Schupf N, Verweij N, Hutri-Kahonen N, Mononen N, Bansal N, Devuyst O, Melander O, Raitakari OT, Polasek O, Manunta P, Gasparini P, Mishra PP, Sulem P, Magnusson PKE, Elliott P, Ridker PM, Hamet P, Svensson PO, Joshi PK, Kovacs P, Pramstaller PP, Rossing P, Vollenweider P, van der Harst P, Dorajoo R, Sim RZH, Burkhardt R, Tao R, Noordam R, Magi R, Schmidt R, de Mutsert R, Rueedi R, van Dam RM, Carroll RJ, Gansevoort RT, Loos RJF, Felicita SC, Sedaghat S, Padmanabhan S, Freitag-Wolf S, Pendergrass SA, Graham SE, Gordon SD, Hwang SJ, Kerr SM, Vaccargiu S, Patil SB, Hallan S, Bakker SJL, Lim SC, Lucae S, Vogelezang S, Bergmann S, Corre T, Ahluwalia TS, Lehtimaki T, Boutin TS, Meitinger T, Wong TY, Bergler T, Rabelink TJ, Esko T, Haller T, Thorsteinsdottir U, Volker U, Foo VHX, Salomaa V, Vitart V, Giedraitis V, Gudnason V, Jaddoe VWV, Huang W, Zhang W, Wei WB, Kiess W, Marz W, Koenig W, Lieb W, Gao X, Sim X, Wang YX, Friedlander Y, Tham YC, Kamatani Y, Okada Y, Milaneschi Y, Yu Z, Lifelines cohort study, Discov E.H.R.MyCode Study, V.A. Million Verteran Program, Stark KJ, Stefansson K, Boger CA, Hung AM, Kronenberg F, Kottgen A, Pattaro C, Heid IM. Commun Biol, 2022 Jun 13; 5(1): 580.
- Serum Cholesterol Efflux Capacity in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy Yanagi Y, Yu RMC, Ahamed W, Yu M, Teo KYC, Tan ACS, Cheng CY, Wong TY, Apte RS, Cheung CMG. Ophthalmol Sci, 2022 Jun; 2(2): 100142.
- Retinal vascular profile in predicting incident cardiometabolic diseases among individuals with diabetes Betzler BK, Sabanayagam C, Tham YC, Cheung CY, Cheng CY, Wong TY, Nusinovici S. Microcirculation, 2022 Jul; 29(4-5): e12772.
- Bidirectional association between glaucoma and chronic kidney disease: A systematic review and meta-analysis Ng FYC, Song H, Tan BKJ, Teo CB, Wong ETY, Boey PY, Cheng CY. EClinicalMedicine, 2022 Jul; 49: 101498.
- Association between body mass index and diabetic retinopathy in Asians: the Asian Eye Epidemiology Consortium (AEEC) study Sabanayagam C, Sultana R, Banu R, Rim T, Tham YC, Mohan S, Chee ML, Wang YX, Nangia V, Fujiwara K, Tai ES, Song SJ, Bikbov MM, Raman R, Cheng CY, Wong TY, Jonas JB. Br J Ophthalmol, 2022 Jul; 106(7): 980-986.
- Six-Year Incidence and Risk Factors for Primary Angle-Closure Disease: The Singapore Epidemiology of Eye Diseases Study Teo ZL, Soh ZD, Tham YC, Yu M, Chee ML, Thakur S, Nongpiur ME, Koh V, Wong TY, Aung T, Cheng CY. Ophthalmology, 2022 Jul; 129(7): 792-802.
- Utilisation of poor-quality optical coherence tomography scans: adjustment algorithm from the Singapore Epidemiology of Eye Diseases (SEED) study Thakur S, Yu M, Tham YC, Majithia S, Soh ZD, Fang XL, Cheung C, Boey PY, Aung T, Wong TY, Cheng CY. Br J Ophthalmol, 2022 Jul; 106(7): 962-969.
- Associations between visual impairment, incident falls and fall frequency among older asians: longitudinal findings from the Singapore Epidemiology of Eye Diseases study Gupta P, Man REK, Fenwick EK, Qian C, Sim R, Majithia S, Tham YC, Sabanayagam C, Wong TY, Cheng CY, Lamoureux EL. Br J Ophthalmol, 2022 Aug 1:bjophthalmol-2021-320873. doi: 10.1136/bjo-2021-320873.
- The Potential of Current Polygenic Risk Scores to Predict High Myopia and Myopic Macular Degeneration in Multiethnic Singapore Adults Kassam I, Foo LL, Lanca C, Xu L, Hoang QV, Cheng CY, Hysi P, Saw SM. Ophthalmology, 2022 Aug; 129(8): 890-902.
- Relationship between dry eye symptoms and quality of life: associations and mediation analysis Lim EWL, Chong CCY, Nusinovici S, Fenwick E, Lamoureux EL, Sabanayagam C, Cheng CY, Tong L. Br J Ophthalmol, 2022 Aug 8.
- Impact of incident age-related macular degeneration and associated vision loss on vision-related quality of life Man REK, Gan ATL, Fenwick EK, Teo KYC, Tan ACS, Cheung GCM, Teo ZL, Kumari N, Wong TY, Cheng CY, Lamoureux EL. Br J Ophthalmol, 2022 Aug; 106(8): 1063-1068.
- A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Lee WJ, Hsiung CA, Warren HR, Ramirez J, Bork-Jensen J, Karhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Mollehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Schonherr S, Forer L, Scholz M, Galesloot TE, Bradfield JP, Ruotsalainen SE, Daw EW, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Le P, Feitosa MF, Wojczynski MK, Hemerich D, Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Noah TL, Verma A, Slieker RC, Lo KS, Zilhao NR, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Emmel C, Schmidt B, Smyth LJ, Canadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kahonen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Sankareswaran A, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers P, Arbeeva L, Dorajoo R, Lange LA, Prasad G, Lores-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Morgan A, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas MP, Vaccargiu S, van der Most PJ, Pitkanen N, Cade BE, van der Laan SW, Chitrala KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikainen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, He KY, Tang H, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jager S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Kahonen M, Perusse L, Bouchard C, Tonjes A, Ida Chen YD, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellstrom D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Zimmermann ME, Volzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Peyser PA, Kato N, Schulze MB, Girotto G, Boger CA, Jung B, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Tusie-Luna T, Aguilar-Salinas CA, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Walker M, Scott LJ, Koistinen HA, Chandak GR, Mercader JM, Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam RM, Lehtimaki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jockel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Lu F, Hishigaki H, Lin X, Marz W, Gudnason V, Tardif JC, Lettre G, LM TH, Elders PJM, Rader DJ, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP, Rotimi CN, Christensen K, Ripatti S, Widen E, Hakonarson H, Grant SFA, Kiemeney L, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, Mannikko M, Jarvelin MR, Kutalik Z, Francesco C, Mook-Kanamori DO, Willems van Dijk K, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Huey-Herng Sheu W, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, de Geus EJC, Cupples LA, van Meurs JBJ, Ikram A, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Tuomilehto J, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A, Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, Asvold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen YE, Ho YL, Lynch JA, Tsao PS, Chang KM, Cho K, O’Donnell CJ, Gaziano JM, Wilson P, Mohlke KL, Frayling TM, Hirschhorn JN, Kathiresan S, Boehnke M, Million Veterans Programm, Global Lipids Genetics Consortium, Struan G, Natarajan P, Sun YV, Morris AP, Deloukas P, Peloso G, Assimes TL, Willer CJ, Zhu X, Brown CD. Am J Hum Genet, 2022 Aug 4; 109(8): 1366-1387.
- Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, Sveinbjornsson G, Winkler TW, Gunther F, Stark KJ, Chai JF, Tayo BO, Wuttke M, Li Y, Tin A, Ahluwalia TS, Arnlov J, Asvold BO, Bakker SJL, Banas B, Bansal N, Biggs ML, Biino G, Bohnke M, Boerwinkle E, Bottinger EP, Brenner H, Brumpton B, Carroll RJ, Chaker L, Chalmers J, Chee ML, Chee ML, Cheng CY, Chu AY, Ciullo M, Cocca M, Cook JP, Coresh J, Cusi D, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Evans MK, Feitosa MF, Franke A, Freitag-Wolf S, Fuchsberger C, Gampawar P, Gansevoort RT, Ghanbari M, Ghasemi S, Giedraitis V, Gieger C, Gudbjartsson DF, Hallan S, Hamet P, Hishida A, Ho K, Hofer E, Holleczek B, Holm H, Hoppmann A, Horn K, Hutri-Kahonen N, Hveem K, Hwang SJ, Ikram MA, Josyula NS, Jung B, Kahonen M, Karabegovic I, Khor CC, Koenig W, Kramer H, Kramer BK, Kuhnel B, Kuusisto J, Laakso M, Lange LA, Lehtimaki T, Li M, Lieb W, Lifelines Cohort Study, Lind L, Lindgren CM, Loos RJF, Lukas MA, Lyytikainen LP, Mahajan A, Matias-Garcia PR, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Morris AP, Mychaleckyj JC, Nadkarni GN, Naito M, Nakatochi M, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Nutile T, O’Donoghue ML, O’Connell J, Olafsson I, Orho-Melander M, Parsa A, Pendergrass SA, Penninx B, Pirastu M, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rheinberger M, Rice KM, Rizzi F, Rosenkranz AR, Rossing P, Rotter JI, Ruggiero D, Ryan KA, Sabanayagam C, Salvi E, Schmidt H, Schmidt R, Scholz M, Schottker B, Schulz CA, Sedaghat S, Shaffer CM, Sieber KB, Sim X, Sims M, Snieder H, Stanzick KJ, Thorsteinsdottir U, Stocker H, Strauch K, Stringham HM, Sulem P, Szymczak S, Taylor KD, Thio CHL, Tremblay J, Vaccargiu S, van der Harst P, van der Most PJ, Verweij N, Volker U, Wakai K, Waldenberger M, Wallentin L, Wallner S, Wang J, Waterworth DM, White HD, Willer CJ, Wong TY, Woodward M, Yang Q, Yerges-Armstrong LM, Zimmermann M, Zonderman AB, Bergler T, Stefansson K, Boger CA, Pattaro C, Kottgen A, Kronenberg F, Heid IM. Kidney Int, 2022 Sep; 102(3): 624-639.
- Computer-aided detection and abnormality score for the outer retinal layer in optical coherence tomography Rim TH, Lee AY, Ting DS, Teo KYC, Yang HS, Kim H, Lee G, Teo ZL, Teo Wei Jun A, Takahashi K, Yoo TK, Kim SE, Yanagi Y, Cheng CY, Kim SS, Wong TY, Cheung CMG. Br J Ophthalmol, 2022 Sep; 106(9): 1301-1307.
- Visual field defects and myopic macular degeneration in Singapore adults with high myopia Lanca C, Sun CH, Chong R, Wong YL, Nongpiur ME, Htoon HM, Thakur S, Quek DQY, Cheng CY, Hoang QV, Sabanayagam C, Saw SM, Wong CW. Br J Ophthalmol, 2022 Oct; 106(10): 1423-1428.
- Evaluation of Generative Adversarial Networks for High-Resolution Synthetic Image Generation of Circumpapillary Optical Coherence Tomography Images for Glaucoma Sreejith Kumar AJ, Chong RS, Crowston JG, Chua J, Bujor I, Husain R, Vithana EN, Girard MJA, Ting DSW, Cheng CY, Aung T, Popa-Cherecheanu A, Schmetterer L, Wong D. JAMA Ophthalmol, 2022 Oct 1; 140(10): 974-981.
- A saturated map of common genetic variants associated with human height Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T, Lin K, Lull K, Malden DE, Medina-Gomez C, Machado M, Moore A, Rueger S, Sim X, Vrieze S, Ahluwalia TS, Akiyama M, Allison MA, Alvarez M, Andersen MK, Ani A, Appadurai V, Arbeeva L, Bhaskar S, Bielak LF, Bollepalli S, Bonnycastle LL, Bork-Jensen J, Bradfield JP, Bradford Y, Braund PS, Brody JA, Burgdorf KS, Cade BE, Cai H, Cai Q, Campbell A, Canadas-Garre M, Catamo E, Chai JF, Chai X, Chang LC, Chang YC, Chen CH, Chesi A, Choi SH, Chung RH, Cocca M, Concas MP, Couture C, Cuellar-Partida G, Danning R, Daw EW, Degenhard F, Delgado GE, Delitala A, Demirkan A, Deng X, Devineni P, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Ekici AB, Engmann JE, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer L, Francescatto M, Freitag-Wolf S, Fuchsberger C, Galesloot TE, Gao Y, Gao Z, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, He J, Heard-Costa N, Hebbar P, Hindy G, Ho YA, Hofer E, Holliday E, Horn K, Hornsby WE, Hottenga JJ, Huang H, Huang J, Huerta-Chagoya A, Huffman JE, Hung YJ, Huo S, Hwang MY, Iha H, Ikeda DD, Isono M, Jackson AU, Jager S, Jansen IE, Johansson I, Jonas JB, Jonsson A, Jorgensen T, Kalafati IP, Kanai M, Kanoni S, Karhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim HN, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee JY, Leonard HL, Li SA, Li X, Li X, Liang J, Lin H, Lin SY, Liu J, Liu X, Lo KS, Long J, Lores-Motta L, Luan J, Lyssenko V, Lyytikainen LP, Mahajan A, Mamakou V, Mangino M, Manichaikul A, Marten J, Mattheisen M, Mavarani L, McDaid AF, Meidtner K, Melendez TL, Mercader JM, Milaneschi Y, Miller JE, Millwood IY, Mishra PP, Mitchell RE, Mollehave LT, Morgan A, Mucha S, Munz M, Nakatochi M, Nelson CP, Nethander M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R, Ntalla I, Nutile T, Pandit A, Christofidou P, Parna K, Pauper M, Petersen ERB, Petersen LV, Pitkanen N, Polasek O, Poveda A, Preuss MH, Pyarajan S, Raffield LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R, Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Saxena R, Scholz M, Sendamarai A, Shen B, Shi J, Shin JH, Sidore C, Sitlani CM, Slieker RC, Smit RAJ, Smith AV, Smith JA, Smyth LJ, Southam L, Steinthorsdottir V, Sun L, Takeuchi F, Tallapragada DSP, Taylor KD, Tayo BO, Tcheandjieu C, Terzikhan N, Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers P, Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wang CA, Wang C, Wang L, Wang Z, Warren HR, Bin Wei W, Wickremasinghe AR, Wielscher M, Wiggins KL, Winsvold BS, Wong A, Wu Y, Wuttke M, Xia R, Xie T, Yamamoto K, Yang J, Yao J, Young H, Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao JH, Zhao W, Zhou W, Zimmermann ME, Zoledziewska M, Adair LS, Adams HHH, Aguilar-Salinas CA, Al-Mulla F, Arnett DK, Asselbergs FW, Asvold BO, Attia J, Banas B, Bandinelli S, Bennett DA, Bergler T, Bharadwaj D, Biino G, Bisgaard H, Boerwinkle E, Boger CA, Bonnelykke K, Boomsma DI, Borglum AD, Borja JB, Bouchard C, Bowden DW, Brandslund I, Brumpton B, Buring JE, Caulfield MJ, Chambers JC, Chandak GR, Chanock SJ, Chaturvedi N, Chen YI, Chen Z, Cheng CY, Christophersen IE, Ciullo M, Cole JW, Collins FS, Cooper RS, Cruz M, Cucca F, Cupples LA, Cutler MJ, Damrauer SM, Dantoft TM, de Borst GJ, de Groot L, De Jager PL, de Kleijn DPV, Janaka de Silva H, Dedoussis GV, den Hollander AI, Du S, Easton DF, Elders PJM, Eliassen AH, Ellinor PT, Elmstahl S, Erdmann J, Evans MK, Fatkin D, Feenstra B, Feitosa MF, Ferrucci L, Ford I, Fornage M, Franke A, Franks PW, Freedman BI, Gasparini P, Gieger C, Girotto G, Goddard ME, Golightly YM, Gonzalez-Villalpando C, Gordon-Larsen P, Grallert H, Grant SFA, Grarup N, Griffiths L, Gudnason V, Haiman C, Hakonarson H, Hansen T, Hartman CA, Hattersley AT, Hayward C, Heckbert SR, Heng CK, Hengstenberg C, Hewitt AW, Hishigaki H, Hoyng CB, Huang PL, Huang W, Hunt SC, Hveem K, Hypponen E, Iacono WG, Ichihara S, Ikram MA, Isasi CR, Jackson RD, Jarvelin MR, Jin ZB, Jockel KH, Joshi PK, Jousilahti P, Jukema JW, Kahonen M, Kamatani Y, Kang KD, Kaprio J, Kardia SLR, Karpe F, Kato N, Kee F, Kessler T, Khera AV, Khor CC, Kiemeney L, Kim BJ, Kim EK, Kim HL, Kirchhof P, Kivimaki M, Koh WP, Koistinen HA, Kolovou GD, Kooner JS, Kooperberg C, Kottgen A, Kovacs P, Kraaijeveld A, Kraft P, Krauss RM, Kumari M, Kutalik Z, Laakso M, Lange LA, Langenberg C, Launer LJ, Le Marchand L, Lee H, Lee NR, Lehtimaki T, Li H, Li L, Lieb W, Lin X, Lind L, Linneberg A, Liu CT, Liu J, Loeffler M, London B, Lubitz SA, Lye SJ, Mackey DA, Magi R, Magnusson PKE, Marcus GM, Vidal PM, Martin NG, Marz W, Matsuda F, McGarrah RW, McGue M, McKnight AJ, Medland SE, Mellstrom D, Metspalu A, Mitchell BD, Mitchell P, Mook-Kanamori DO, Morris AD, Mucci LA, Munroe PB, Nalls MA, Nazarian S, Nelson AE, Neville MJ, Newton-Cheh C, Nielsen CS, Nothen MM, Ohlsson C, Oldehinkel AJ, Orozco L, Pahkala K, Pajukanta P, Palmer CNA, Parra EJ, Pattaro C, Pedersen O, Pennell CE, Penninx B, Perusse L, Peters A, Peyser PA, Porteous DJ, Posthuma D, Power C, Pramstaller PP, Province MA, Qi Q, Qu J, Rader DJ, Raitakari OT, Ralhan S, Rallidis LS, Rao DC, Redline S, Reilly DF, Reiner AP, Rhee SY, Ridker PM, Rienstra M, Ripatti S, Ritchie MD, Roden DM, Rosendaal FR, Rotter JI, Rudan I, Rutters F, Sabanayagam C, Saleheen D, Salomaa V, Samani NJ, Sanghera DK, Sattar N, Schmidt B, Schmidt H, Schmidt R, Schulze MB, Schunkert H, Scott LJ, Scott RJ, Sever P, Shiroma EJ, Shoemaker MB, Shu XO, Simonsick EM, Sims M, Singh JR, Singleton AB, Sinner MF, Smith JG, Snieder H, Spector TD, Stampfer MJ, Stark KJ, Strachan DP, t Hart LM, Tabara Y, Tang H, Tardif JC, Thanaraj TA, Timpson NJ, Tonjes A, Tremblay A, Tuomi T, Tuomilehto J, Tusie-Luna MT, Uitterlinden AG, van Dam RM, van der Harst P, Van der Velde N, van Duijn CM, van Schoor NM, Vitart V, Volker U, Vollenweider P, Volzke H, Wacher-Rodarte NH, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Weir DR, Werge TM, Widen E, Wilkens LR, Willemsen G, Willett WC, Wilson JF, Wong TY, Woo JT, Wright AF, Wu JY, Xu H, Yajnik CS, Yokota M, Yuan JM, Zeggini E, Zemel BS, Zheng W, Zhu X, Zmuda JM, Zonderman AB, Zwart JA, and Me Research Team, V.A. Million Veteran Program, Discov Ehr eMerge, Lifelines Cohort Study, Practical Consortium, Understanding Society Scientific Group, Chasman DI, Cho YS, Heid IM, McCarthy MI, Ng MCY, O’Donnell CJ, Rivadeneira F, Thorsteinsdottir U, Sun YV, Tai ES, Boehnke M, Deloukas P, Justice AE, Lindgren CM, Loos RJF, Mohlke KL, North KE, Stefansson K, Walters RG, Winkler TW, Young KL, Loh PR, Yang J, Esko T, Assimes TL, Auton A, Abecasis GR, Willer CJ, Locke AE, Berndt SI, Lettre G, Frayling TM, Okada Y, Wood AR, Visscher PM, Hirschhorn JN. Nature, 2022 Oct; 610(7933): 704-712.
- Analysis of clinically relevant variants from ancestrally diverse Asian genomes Chan SH, Bylstra Y, Teo JX, Kuan JL, Bertin N, Gonzalez-Porta M, Hebrard M, Tirado-Magallanes R, Tan JHJ, Jeyakani J, Li Z, Chai JF, Chong YS, Davila S, Goh LL, Lee ES, Wong E, Wong TY, S. G10K_Health Consortium, Prabhakar S, Liu J, Cheng CY, Eisenhaber B, Karnani N, Leong KP, Sim X, Yeo KK, Chambers JC, Tai ES, Tan P, Jamuar SS, Ngeow J, Lim WK. Nat Commun, 2022 Nov 5; 13(1): 6694.
- A deep learning model for detection of Alzheimer’s disease based on retinal photographs: a retrospective, multicentre case-control study Cheung CY, Ran AR, Wang S, Chan VTT, Sham K, Hilal S, Venketasubramanian N, Cheng CY, Sabanayagam C, Tham YC, Schmetterer L, McKay GJ, Williams MA, Wong A, Au LWC, Lu Z, Yam JC, Tham CC, Chen JJ, Dumitrascu OM, Heng PA, Kwok TCY, Mok VCT, Milea D, Chen CL, Wong TY. Lancet Digit Health, 2022 Nov; 4(11): e806-e815.
- Normative Data and Associations of OCT Angiography Measurements of the Macula: The Singapore Malay Eye Study Teo ZL, Sun CZ, Chong CCY, Tham YC, Takahashi K, Majithia S, Teo CL, Rim TH, Chua J, Schmetterer L, Cheung CMG, Wong TY, Cheng CY, Tan ACS. Ophthalmol Retina, 2022 Nov; 6(11): 1080-1088.
- Haploinsufficiency of CYP8B1 associates with increased insulin sensitivity in humans Zhong S, Chevre R, Castano Mayan D, Corliano M, Cochran BJ, Sem KP, van Dijk TH, Peng J, Tan LJ, Hartimath SV, Ramasamy B, Cheng P, Groen AK, Kuipers F, Goggi JL, Drum C, van Dam RM, Tan RS, Rye KA, Hayden MR, Cheng CY, Chacko S, Flannick J, Sim X, Tan HC, Singaraja RR. J Clin Invest, 2022 Nov 1; 132(21).
- Deep learning algorithms for automatic detection of pterygium using anterior segment photographs from slit-lamp and hand-held cameras Fang X, Deshmukh M, Chee ML, Soh ZD, Teo ZL, Thakur S, Goh JHL, Liu YC, Husain R, Mehta JS, Wong TY, Cheng CY, Rim TH, Tham YC. Br J Ophthalmol, 2022 Dec; 106(12): 1642-1647.
- Association Between Risk of Obstructive Sleep Apnea and Glaucoma: The Singapore Epidemiology of Eye Diseases Study Mehta A, Man REK, Gan AT, Najjar RP, Nongpiur M, Lamoureux EL, Cheng CY, Fenwick EK. J Glaucoma, 2022 Dec 1; 31(12): 935-940.
- Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Yousri NA, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Hwu CM, Hung YJ, Warren HR, Ramirez J, Bork-Jensen J, Karhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, Mollehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Ruotsalainen SE, Daw E, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Vazquez-Moreno M, Feitosa MF, Wojczynski MK, Wang Z, Preuss MH, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Tsao NL, Verma A, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Frank M, Schmidt B, Smyth LJ, Canadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Kahonen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Bayyana S, Stringham HM, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers P, Arbeeva L, Dorajoo R, Lange LA, Prasad G, Lores-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Nardone GG, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas MP, Vaccargiu S, van der Most PJ, Pitkanen N, Cade BE, van der Laan SW, Chitrala KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikainen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Liang J, Tang H, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jager S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Kahonen M, Perusse L, Bouchard C, Tonjes A, Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellstrom D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Zimmermann ME, Volzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Kardia SLR, Peyser PA, Kato N, Schulze MB, Girotto G, Boger CA, Jung B, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Tusie-Luna T, Aguilar-Salinas CA, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Hunt SC, Walker M, Koistinen HA, Chandak GR, Mercader JM, Costanzo MC, Jang D, Burtt NP, Villalpando CG, Orozco L, Fornage M, Tai E, van Dam RM, Lehtimaki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jockel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Qu J, Hishigaki H, Lin X, Marz W, Gudnason V, Tardif JC, Lettre G, Hart LM, Elders PJM, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP, Rotimi CN, Christensen K, Ripatti S, Widen E, Hakonarson H, Grant SFA, Kiemeney L, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, Mannikko M, Jarvelin MR, Kutalik Z, Francesco C, Mook-Kanamori DO, van Dijk KW, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Chuang LM, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, Willemsen AHM, Cupples L, van Meurs JBJ, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A, Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, Asvold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen Y, Ho YL, Lynch JA, Rader DJ, Tsao PS, Chang KM, Cho K, O’Donnell CJ, Gaziano JM, Wilson PWF, Frayling TM, Hirschhorn JN, Kathiresan S, Mohlke KL, Sun YV, Morris AP, Boehnke M, Brown CD, Natarajan P, Deloukas P, Willer CJ, Assimes TL, Peloso GM. Genome Biol, 2022 Dec 27; 23(1): 268.
- Predictive, preventive, and personalized management of retinal fluid via computer-aided detection app for optical coherence tomography scans Quek TC, Takahashi K, Kang HG, Thakur S, Deshmukh M, Tseng R, Nguyen H, Tham YC, Rim TH, Kim SS, Yanagi Y, Liew G, Cheng CY. EPMA J, 2022 Dec; 13(4): 547-560.
- Relationships between Lipid-Related Metabolites and Age-Related Macular Degeneration Vary with Complement Genotype Sim RZH, Tham YC, Betzler BK, Zhou L, Wang X, Sabanayagam C, Cheung GCM, Wong TY, Cheng CY, Nusinovici S. Ophthalmol Sci, 2022 Dec; 2(4): 100211.
- Artificial Intelligence in Predicting Systemic Parameters and Diseases From Ophthalmic Imaging Betzler BK, Rim TH, Sabanayagam C, Cheng CY. Front Digit Health, 2022a; 4: 889445.
- Impact of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) GFR Estimating Equations on CKD Prevalence and Classification Among Asians Betzler BK, Sultana R, He F, Tham YC, Lim CC, Wang YX, Nangia V, Tai ES, Rim TH, Bikbov MM, Jonas JB, Kang SW, Park KH, Cheng CY, Sabanayagam C. Front Med (Lausanne), 2022b; 9: 957437.
- The discriminant validity of single-question assessments of subjective cognitive complaints in an Asian older adult population Pang T, Zhao X, He X, Kan CN, Venketasubramanian N, Cheng CY, Yuan C, Chen C, Xu X. Front Aging Neurosci, 2022; 14: 901592.
- Three-Dimensional Multi-Task Deep Learning Model to Detect Glaucomatous Optic Neuropathy and Myopic Features From Optical Coherence Tomography Scans: A Retrospective Multi-Centre Study Ran AR, Wang X, Chan PP, Chan NC, Yip W, Young AL, Wong MOM, Yung HW, Chang RT, Mannil SS, Tham YC, Cheng CY, Chen H, Li F, Zhang X, Heng PA, Tham CC, Cheung CY. Front Med (Lausanne), 2022; 9: 860574.
2021
- Ethnic differences in the incidence of pterygium in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Diseases Study Fang XL, Chong CCY, Thakur S, Da Soh Z, Teo ZL, Majithia S, Lim ZW, Rim TH, Sabanayagam C, Wong TY, Cheng CY, Tham YC. Sci Rep, 2021 Jan 12; 11(1): 501.
- Referral for disease-related visual impairment using retinal photograph-based deep learning: a proof-of-concept, model development study Tham YC, Anees A, Zhang L, Goh JHL, Rim TH, Nusinovici S, Hamzah H, Chee ML, Tjio G, Li S, Xu X, Goh R, Tang F, Cheung CY, Wang YX, Nangia V, Jonas JB, Gopinath B, Mitchell P, Husain R, Lamoureux E, Sabanayagam C, Wang JJ, Aung T, Liu Y, Wong TY, Cheng CY. Lancet Digit Health, 2021 Jan; 3(1): e29-e40.
- Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries Gharahkhani P, Jorgenson E, Hysi P, Khawaja AP, Pendergrass S, Han X, Ong JS, Hewitt AW, Segre AV, Rouhana JM, Hamel AR, Igo RP, Jr., Choquet H, Qassim A, Josyula NS, Cooke Bailey JN, Bonnemaijer PWM, Iglesias A, Siggs OM, Young TL, Vitart V, Thiadens A, Karjalainen J, Uebe S, Melles RB, Nair KS, Luben R, Simcoe M, Amersinghe N, Cree AJ, Hohn R, Poplawski A, Chen LJ, Rong SS, Aung T, Vithana EN, Neighborhood Consortium, Anzrag Consortium, Biobank Japan project, FinnGen study, U.K. Biobank Eye Vision Consortium, Giga study group, Me Research Team, Tamiya G, Shiga Y, Yamamoto M, Nakazawa T, Currant H, Birney E, Wang X, Auton A, Lupton MK, Martin NG, Ashaye A, Olawoye O, Williams SE, Akafo S, Ramsay M, Hashimoto K, Kamatani Y, Akiyama M, Momozawa Y, Foster PJ, Khaw PT, Morgan JE, Strouthidis NG, Kraft P, Kang JH, Pang CP, Pasutto F, Mitchell P, Lotery AJ, Palotie A, van Duijn C, Haines JL, Hammond C, Pasquale LR, Klaver CCW, Hauser M, Khor CC, Mackey DA, Kubo M, Cheng CY, Craig JE, MacGregor S, Wiggs JL. Nat Commun, 2021 Feb 24; 12(1): 1258.
- The Impact of Strategic White Matter Hyperintensity Lesion Location on Language Hilal S, Biesbroek JM, Vrooman H, Chong E, Kuijf HJ, Venketasubramanian N, Cheng CY, Wong TY, Biessels GJ, Chen C. Am J Geriatr Psychiatry, 2021 Feb; 29(2): 156-165.
- Prevalence of retinitis pigmentosa in Singapore: the Singapore Epidemiology of Eye Diseases Study Teo CL, Cheung N, Poh S, Thakur S, Rim TH, Cheng CY, Tham YC. Acta Ophthalmol, 2021 Feb; 99(1): e134-e135.
- Association of Antihypertensive Medication with Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer Thickness Chong RS, Chee ML, Tham YC, Majithia S, Thakur S, Teo ZL, Da Soh Z, Chua J, Tan B, Wong DWK, Schmetterer L, Sabanayagam C, Cheng CY. Ophthalmology, 2021 Mar; 128(3): 393-400.
- Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci for Estimating Angle Closure Disease Severity Liu C, Nongpiur ME, Cheng CY, Khor CC, Yu M, Husain R, Ho CL, Wong TT, Boey PY, Perera S, Wong TY, Vithana EN, Aung T. Ophthalmology, 2021 Mar; 128(3): 403-409.
- Role of socio-economic factors in visual impairment and progression of diabetic retinopathy Low JR, Gan ATL, Fenwick EK, Gupta P, Wong TY, Teo ZL, Thakur S, Tham YC, Sabanayagam C, Cheng CY, Lamoureux EL, Man REK. Br J Ophthalmol, 2021 Mar; 105(3): 420-425.
- A systematic review and participant-level meta-analysis found little association of retinal microvascular caliber with reduced kidney function Lye WK, Paterson E, Patterson CC, Maxwell AP, Binte Mohammed Abdul RB, Tai ES, Cheng CY, Kayama T, Yamashita H, Sarnak M, Shlipak M, Matsushita K, Mutlu U, Ikram MA, Klaver C, Kifley A, Mitchell P, Myers C, Klein BE, Klein R, Wong TY, Sabanayagam C, McKay GJ. Kidney Int, 2021 Mar; 99(3): 696-706.
- Cohort Profile: The Singapore Epidemiology of Eye Diseases study (SEED) Majithia S, Tham YC, Chee ML, Nusinovici S, Teo CL, Chee ML, Thakur S, Soh ZD, Kumari N, Lamoureux E, Sabanayagam C, Wong TY, Cheng CY. Int J Epidemiol, 2021 Mar 3; 50(1): 41-52.
- The Differential Impact of Age on Vision-Related Quality of Life across the Visual Impairment Spectrum Man REK, Gan ATL, Fenwick EK, Gupta P, Thakur S, Fang XL, Cheng CY, Wong TY, Lamoureux EL. Ophthalmology, 2021 Mar; 128(3): 354-363.
- Retinal microvascular signs and risk of diabetic kidney disease in asian and white populations Nusinovici S, Sabanayagam C, Lee KE, Zhang L, Cheung CY, Tai ES, Tan GSW, Cheng CY, Klein BEK, Wong TY. Sci Rep, 2021 Mar 1; 11(1): 4898.
- Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color Simcoe M, Valdes A, Liu F, Furlotte NA, Evans DM, Hemani G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Vuckovic D, Girotto G, Sala C, Catamo E, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt A, Wu W, Kraft P, Hammond CJ, Shi Y, Chen Y, Zeng C, Klaver CCW, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Han J, Mackey DA, Martin NG, Cheng CY, and Me Research Team, International Visible Trait Genetics Consortium, Hinds DA, Spector TD, Kayser M, Hysi PG. Sci Adv, 2021 Mar; 7(11).
- Determinants of lamina cribrosa depth in healthy Asian eyes: the Singapore Epidemiology Eye Study Tun TA, Wang X, Baskaran M, Nongpiur ME, Tham YC, Nguyen DQ, Strouthidis NG, Aung T, Cheng CY, Boote C, Girard MJA. Br J Ophthalmol, 2021 Mar; 105(3): 367-373.
- Factors affecting the diagnostic performance of circumpapillary retinal nerve fibre layer measurement in glaucoma Wong D, Chua J, Baskaran M, Tan B, Yao X, Chan S, Tham YC, Chong R, Aung T, Lamoureux EL, Vithana EN, Cheng CY, Schmetterer L. Br J Ophthalmol, 2021 Mar; 105(3): 397-402.
- Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide-field optical coherence tomography in Singapore adults with high myopia Zheng F, Wong CW, Sabanayagam C, Cheung YB, Matsumura S, Chua J, Man REK, Ohno-Matsui K, Wong TY, Cheng CY, Tai ES, Lamoureux E, Schmetterer L, Kuo A, Hoang QV, Saw SM. Acta Ophthalmol, 2021 Mar; 99(2): e144-e153.
- Six-Year Incidence and Risk Factors of Primary Glaucoma in the Singapore Indian Eye Study Koh V, Tham YC, Tan NYQ, Yu M, Thakur S, Teo ZL, Mani B, Wong TY, Aung T, Cheng CY. Ophthalmol Glaucoma, 2021 Mar-Apr; 4(2): 201-208.
- Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline Gorski M, Jung B, Li Y, Matias-Garcia PR, Wuttke M, Coassin S, Thio CHL, Kleber ME, Winkler TW, Wanner V, Chai JF, Chu AY, Cocca M, Feitosa MF, Ghasemi S, Hoppmann A, Horn K, Li M, Nutile T, Scholz M, Sieber KB, Teumer A, Tin A, Wang J, Tayo BO, Ahluwalia TS, Almgren P, Bakker SJL, Banas B, Bansal N, Biggs ML, Boerwinkle E, Bottinger EP, Brenner H, Carroll RJ, Chalmers J, Chee ML, Chee ML, Cheng CY, Coresh J, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Franke A, Freitag-Wolf S, Gampawar P, Gansevoort RT, Ghanbari M, Gieger C, Hamet P, Ho K, Hofer E, Holleczek B, Xian Foo VH, Hutri-Kahonen N, Hwang SJ, Ikram MA, Josyula NS, Kahonen M, Khor CC, Koenig W, Kramer H, Kramer BK, Kuhnel B, Lange LA, Lehtimaki T, Lieb W, Lifelines Cohort Study, Regeneron Genetics Center, Loos RJF, Lukas MA, Lyytikainen LP, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Mychaleckyj JC, Nadkarni GN, Nauck M, Nikus K, Ning B, Nolte IM, O’Donoghue ML, Orho-Melander M, Pendergrass SA, Penninx B, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rosenkranz AR, Rossing P, Rotter JI, Sabanayagam C, Schmidt H, Schmidt R, Schottker B, Schulz CA, Sedaghat S, Shaffer CM, Strauch K, Szymczak S, Taylor KD, Tremblay J, Chaker L, van der Harst P, van der Most PJ, Verweij N, Volker U, Waldenberger M, Wallentin L, Waterworth DM, White HD, Wilson JG, Wong TY, Woodward M, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang Y, Snieder H, Wanner C, Boger CA, Kottgen A, Kronenberg F, Pattaro C, Heid IM. Kidney Int, 2021 Apr; 99(4): 926-939.
- Association of alcohol intake with incidence and progression of diabetic retinopathy Gupta P, Fenwick EK, Sabanayagam C, Gan ATL, Tham YC, Thakur S, Man REK, Mitchell P, Wong TY, Cheng CY, Lamoureux EL. Br J Ophthalmol, 2021 Apr; 105(4): 538-542.
- Characteristics of myopic traction maculopathy in myopic Singaporean adults Matsumura S, Sabanayagam C, Wong CW, Tan CS, Kuo A, Wong YL, Ohno-Matsui K, Wong TY, Cheng CY, Hoang QV, Saw SM. Br J Ophthalmol, 2021 Apr; 105(4): 531-537.
- Albuminuria and Primary Open-Angle Glaucoma: the Singapore Chinese Eye Study (SCES) Lim ZW, Chee ML, Thakur S, Fang X, Soh ZD, Majithia S, Teo ZL, Sabanayagam C, Wong TY, Cheng CY, Tham YC. Br J Ophthalmol, 2021 May; 105(5): 669-673.
- Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs Rim TH, Lee CJ, Tham YC, Cheung N, Yu M, Lee G, Kim Y, Ting DSW, Chong CCY, Choi YS, Yoo TK, Ryu IH, Baik SJ, Kim YA, Kim SK, Lee SH, Lee BK, Kang SM, Wong EYM, Kim HC, Kim SS, Park S, Cheng CY, Wong TY. Lancet Digit Health, 2021 May; 3(5): e306-e316.
- Patterns and Determinants of Choroidal Thickness in a Multiethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study Song Y, Tham YC, Chong C, Ong R, Fenner BJ, Cheong KX, Takahashi K, Jordan-Yu JM, Teo KYC, Tan ACS, Cheng CY, Wong TY, Chakravarthy U, Yanagi Y, Cheung GCM. Ophthalmol Retina, 2021 May; 5(5): 458-467.
- Retinal photograph-based deep learning algorithms for myopia and a blockchain platform to facilitate artificial intelligence medical research: a retrospective multicohort study Tan TE, Anees A, Chen C, Li S, Xu X, Li Z, Xiao Z, Yang Y, Lei X, Ang M, Chia A, Lee SY, Wong EYM, Yeo IYS, Wong YL, Hoang QV, Wang YX, Bikbov MM, Nangia V, Jonas JB, Chen YP, Wu WC, Ohno-Matsui K, Rim TH, Tham YC, Goh RSM, Lin H, Liu H, Wang N, Yu W, Tan DTH, Schmetterer L, Cheng CY, Chen Y, Wong CW, Cheung GCM, Saw SM, Wong TY, Liu Y, Ting DSW. Lancet Digit Health, 2021 May; 3(5): e317-e329.
- COVID-19 awareness, knowledge and perception towards digital health in an urban multi-ethnic Asian population Teo CL, Chee ML, Koh KH, Tseng R, Majithia S, Thakur S, Gunasekeran DV, Nusinovici S, Sabanayagam C, Wong TY, Tham YC, Cheng CY. Sci Rep, 2021 May 24; 11(1): 10795.
- The trans-ancestral genomic architecture of glycemic traits Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Magi R, Waage J, Li-Gao R, Chan KHK, Yao J, Anasanti MD, Chu AY, Claringbould A, Heikkinen J, Hong J, Hottenga JJ, Huo S, Kaakinen MA, Louie T, Marz W, Moreno-Macias H, Ndungu A, Nelson SC, Nolte IM, North KE, Raulerson CK, Ray D, Rohde R, Rybin D, Schurmann C, Sim X, Southam L, Stewart ID, Wang CA, Wang Y, Wu P, Zhang W, Ahluwalia TS, Appel EVR, Bielak LF, Brody JA, Burtt NP, Cabrera CP, Cade BE, Chai JF, Chai X, Chang LC, Chen CH, Chen BH, Chitrala KN, Chiu YF, de Haan HG, Delgado GE, Demirkan A, Duan Q, Engmann J, Fatumo SA, Gayan J, Giulianini F, Gong JH, Gustafsson S, Hai Y, Hartwig FP, He J, Heianza Y, Huang T, Huerta-Chagoya A, Hwang MY, Jensen RA, Kawaguchi T, Kentistou KA, Kim YJ, Kleber ME, Kooner IK, Lai S, Lange LA, Langefeld CD, Lauzon M, Li M, Ligthart S, Liu J, Loh M, Long J, Lyssenko V, Mangino M, Marzi C, Montasser ME, Nag A, Nakatochi M, Noce D, Noordam R, Pistis G, Preuss M, Raffield L, Rasmussen-Torvik LJ, Rich SS, Robertson NR, Rueedi R, Ryan K, Sanna S, Saxena R, Schraut KE, Sennblad B, Setoh K, Smith AV, Sparso T, Strawbridge RJ, Takeuchi F, Tan J, Trompet S, van den Akker E, van der Most PJ, Verweij N, Vogel M, Wang H, Wang C, Wang N, Warren HR, Wen W, Wilsgaard T, Wong A, Wood AR, Xie T, Zafarmand MH, Zhao JH, Zhao W, Amin N, Arzumanyan Z, Astrup A, Bakker SJL, Baldassarre D, Beekman M, Bergman RN, Bertoni A, Bluher M, Bonnycastle LL, Bornstein SR, Bowden DW, Cai Q, Campbell A, Campbell H, Chang YC, de Geus EJC, Dehghan A, Du S, Eiriksdottir G, Farmaki AE, Franberg M, Fuchsberger C, Gao Y, Gjesing AP, Goel A, Han S, Hartman CA, Herder C, Hicks AA, Hsieh CH, Hsueh WA, Ichihara S, Igase M, Ikram MA, Johnson WC, Jorgensen ME, Joshi PK, Kalyani RR, Kandeel FR, Katsuya T, Khor CC, Kiess W, Kolcic I, Kuulasmaa T, Kuusisto J, Lall K, Lam K, Lawlor DA, Lee NR, Lemaitre RN, Li H, Lifelines Cohort Study, Lin SY, Lindstrom J, Linneberg A, Liu J, Lorenzo C, Matsubara T, Matsuda F, Mingrone G, Mooijaart S, Moon S, Nabika T, Nadkarni GN, Nadler JL, Nelis M, Neville MJ, Norris JM, Ohyagi Y, Peters A, Peyser PA, Polasek O, Qi Q, Raven D, Reilly DF, Reiner A, Rivideneira F, Roll K, Rudan I, Sabanayagam C, Sandow K, Sattar N, Schurmann A, Shi J, Stringham HM, Taylor KD, Teslovich TM, Thuesen B, Timmers P, Tremoli E, Tsai MY, Uitterlinden A, van Dam RM, van Heemst D, van Hylckama Vlieg A, van Vliet-Ostaptchouk JV, Vangipurapu J, Vestergaard H, Wang T, Willems van Dijk K, Zemunik T, Abecasis GR, Adair LS, Aguilar-Salinas CA, Alarcon-Riquelme ME, An P, Aviles-Santa L, Becker DM, Beilin LJ, Bergmann S, Bisgaard H, Black C, Boehnke M, Boerwinkle E, Bohm BO, Bonnelykke K, Boomsma DI, Bottinger EP, Buchanan TA, Canouil M, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Cheng CY, Collins FS, Correa A, Cucca F, de Silva HJ, Dedoussis G, Elmstahl S, Evans MK, Ferrannini E, Ferrucci L, Florez JC, Franks PW, Frayling TM, Froguel P, Gigante B, Goodarzi MO, Gordon-Larsen P, Grallert H, Grarup N, Grimsgaard S, Groop L, Gudnason V, Guo X, Hamsten A, Hansen T, Hayward C, Heckbert SR, Horta BL, Huang W, Ingelsson E, James PS, Jarvelin MR, Jonas JB, Jukema JW, Kaleebu P, Kaplan R, Kardia SLR, Kato N, Keinanen-Kiukaanniemi SM, Kim BJ, Kivimaki M, Koistinen HA, Kooner JS, Korner A, Kovacs P, Kuh D, Kumari M, Kutalik Z, Laakso M, Lakka TA, Launer LJ, Leander K, Li H, Lin X, Lind L, Lindgren C, Liu S, Loos RJF, Magnusson PKE, Mahajan A, Metspalu A, Mook-Kanamori DO, Mori TA, Munroe PB, Njolstad I, O’Connell JR, Oldehinkel AJ, Ong KK, Padmanabhan S, Palmer CNA, Palmer ND, Pedersen O, Pennell CE, Porteous DJ, Pramstaller PP, Province MA, Psaty BM, Qi L, Raffel LJ, Rauramaa R, Redline S, Ridker PM, Rosendaal FR, Saaristo TE, Sandhu M, Saramies J, Schneiderman N, Schwarz P, Scott LJ, Selvin E, Sever P, Shu XO, Slagboom PE, Small KS, Smith BH, Snieder H, Sofer T, Sorensen TIA, Spector TD, Stanton A, Steves CJ, Stumvoll M, Sun L, Tabara Y, Tai ES, Timpson NJ, Tonjes A, Tuomilehto J, Tusie T, Uusitupa M, van der Harst P, van Duijn C, Vitart V, Vollenweider P, Vrijkotte TGM, Wagenknecht LE, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Wei WB, Wickremasinghe AR, Willemsen G, Wilson JF, Wong TY, Wu JY, Xiang AH, Yanek LR, Yengo L, Yokota M, Zeggini E, Zheng W, Zonderman AB, Rotter JI, Gloyn AL, McCarthy MI, Dupuis J, Meigs JB, Scott RA, Prokopenko I, Leong A, Liu CT, Parker SCJ, Mohlke KL, Langenberg C, Wheeler E, Morris AP, Barroso I, Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC). Nat Genet, 2021 Jun; 53(6): 840-860.
- A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre Cheung CY, Xu D, Cheng CY, Sabanayagam C, Tham YC, Yu M, Rim TH, Chai CY, Gopinath B, Mitchell P, Poulton R, Moffitt TE, Caspi A, Yam JC, Tham CC, Jonas JB, Wang YX, Song SJ, Burrell LM, Farouque O, Li LJ, Tan G, Ting DSW, Hsu W, Lee ML, Wong TY.Nat Biomed Eng, 2021 Jun; 5(6): 498-508.
- Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci de Las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR, Guo X, Manning A, Chasman DI, Aschard H, Bartz TM, Bielak LF, Campbell A, Cheng CY, Dorajoo R, Hartwig FP, Horimoto A, Li C, Li-Gao R, Liu Y, Marten J, Musani SK, Ntalla I, Rankinen T, Richard M, Sim X, Smith AV, Tajuddin SM, Tayo BO, Vojinovic D, Warren HR, Xuan D, Alver M, Boissel M, Chai JF, Chen X, Christensen K, Divers J, Evangelou E, Gao C, Girotto G, Harris SE, He M, Hsu FC, Kuhnel B, Laguzzi F, Li X, Lyytikainen LP, Nolte IM, Poveda A, Rauramaa R, Riaz M, Rueedi R, Shu XO, Snieder H, Sofer T, Takeuchi F, Verweij N, Ware EB, Weiss S, Yanek LR, Amin N, Arking DE, Arnett DK, Bergmann S, Boerwinkle E, Brody JA, Broeckel U, Brumat M, Burke G, Cabrera CP, Canouil M, Chee ML, Chen YI, Cocca M, Connell J, de Silva HJ, de Vries PS, Eiriksdottir G, Faul JD, Fisher V, Forrester T, Fox EF, Friedlander Y, Gao H, Gigante B, Giulianini F, Gu CC, Gu D, Harris TB, He J, Heikkinen S, Heng CK, Hunt S, Ikram MA, Irvin MR, Kahonen M, Kavousi M, Khor CC, Kilpelainen TO, Koh WP, Komulainen P, Kraja AT, Krieger JE, Langefeld CD, Li Y, Liang J, Liewald DCM, Liu CT, Liu J, Lohman KK, Magi R, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mook-Kanamori DO, Nalls MA, Nelson CP, Norris JM, O’Connell J, Ogunniyi A, Padmanabhan S, Palmer ND, Pedersen NL, Perls T, Peters A, Petersmann A, Peyser PA, Polasek O, Porteous DJ, Raffel LJ, Rice TK, Rotter JI, Rudan I, Rueda-Ochoa OL, Sabanayagam C, Salako BL, Schreiner PJ, Shikany JM, Sidney SS, Sims M, Sitlani CM, Smith JA, Starr JM, Strauch K, Swertz MA, Teumer A, Tham YC, Uitterlinden AG, Vaidya D, van der Ende MY, Waldenberger M, Wang L, Wang YX, Wei WB, Weir DR, Wen W, Yao J, Yu B, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Bowden DW, Deary IJ, Dorr M, Esko T, Freedman BI, Froguel P, Gasparini P, Gieger C, Jonas JB, Kammerer CM, Kato N, Lakka TA, Leander K, Lehtimaki T, Lifelines Cohort Study, Magnusson PKE, Marques-Vidal P, Penninx B, Samani NJ, van der Harst P, Wagenknecht LE, Wu T, Zheng W, Zhu X, Bouchard C, Cooper RS, Correa A, Evans MK, Gudnason V, Hayward C, Horta BL, Kelly TN, Kritchevsky SB, Levy D, Palmas WR, Pereira AC, Province MM, Psaty BM, Ridker PM, Rotimi CN, Tai ES, van Dam RM, van Duijn CM, Wong TY, Rice K, Gauderman WJ, Morrison AC, North KE, Kardia SLR, Caulfield MJ, Elliott P, Munroe PB, Franks PW, Rao DC, Fornage M. Mol Psychiatry, 2021 Jun; 26(6): 2111-2125.
- Vision, vision-specific functioning and mobility, and their relationship with clinically assessed cognitive impairment Fenwick EK, Gan ATL, Man REK, Gupta P, Sabanayagam C, Cheng CY, Chen CL, Cheung CY, Wong KH, Venketasubramanian N, Xu X, Hilal S, Chong EJY, Tham YC, Wong TY, Lamoureux EL. Age Ageing, 2021 Jun 28; 50(4): 1236-1242.
- Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, Dahl A, Aguilar-Salinas CA, Atzmon G, Barajas-Olmos F, Barzilai N, Blangero J, Boerwinkle E, Bonnycastle LL, Bottinger E, Bowden DW, Centeno-Cruz F, Chambers JC, Chami N, Chan E, Chan J, Cheng CY, Cho YS, Contreras-Cubas C, Cordova E, Correa A, DeFronzo RA, Duggirala R, Dupuis J, Garay-Sevilla ME, Garcia-Ortiz H, Gieger C, Glaser B, Gonzalez-Villalpando C, Gonzalez ME, Grarup N, Groop L, Gross M, Haiman C, Han S, Hanis CL, Hansen T, Heard-Costa NL, Henderson BE, Hernandez JMM, Hwang MY, Islas-Andrade S, Jorgensen ME, Kang HM, Kim BJ, Kim YJ, Koistinen HA, Kooner JS, Kuusisto J, Kwak SH, Laakso M, Lange L, Lee JY, Lee J, Lehman DM, Linneberg A, Liu J, Loos RJF, Lyssenko V, Ma RCW, Martinez-Hernandez A, Meigs JB, Meitinger T, Mendoza-Caamal E, Mohlke KL, Morris AD, Morrison AC, Ng MCY, Nilsson PM, O’Donnell CJ, Orozco L, Palmer CNA, Park KS, Post WS, Pedersen O, Preuss M, Psaty BM, Reiner AP, Revilla-Monsalve C, Rich SS, Rotter JI, Saleheen D, Schurmann C, Sim X, Sladek R, Small KS, So WY, Spector TD, Strauch K, Strom TM, Tai ES, Tam CHT, Teo YY, Thameem F, Tomlinson B, Tracy RP, Tuomi T, Tuomilehto J, Tusie-Luna T, van Dam RM, Vasan RS, Wilson JG, Witte DR, Wong TY, Consortia A-TDG, Burtt NP, Zaitlen N, McCarthy MI, Boehnke M, Pollin TI, Flannick J, Mercader JM, O’Donnell-Luria A, Baxter S, Florez JC, MacArthur DG, Udler MS. Nat Commun, 2021 Jun 9; 12(1): 3505.
- Proposal and validation of a new grading system for pterygium (SLIT2) Ting DSJ, Liu YC, Patil M, Ji AJS, Fang XL, Tham YC, Lee YF, Htoon HM, Mehta JS. Br J Ophthalmol, 2021 Jul; 105(7): 921-924.
- The Bidirectional Relationship between Vision and Cognition: A Systematic Review and Meta-analysis Vu TA, Fenwick EK, Gan ATL, Man REK, Tan BKJ, Gupta P, Ho KC, Reyes-Ortiz CA, Trompet S, Gussekloo J, O’Brien JM, Mueller-Schotte S, Wong TY, Tham YC, Cheng CY, Lee ATC, Rait G, Swenor BK, Varadaraj V, Brenowitz WD, Medeiros FA, Nael V, Narasimhalu K, Chen CLH, Lamoureux EL. Ophthalmology, 2021 Jul; 128(7): 981-992.
- Impact of type 2 diabetes and microvascular complications on mortality and cardiovascular outcomes in a multiethnic Asian population Yap J, Anbalakan K, Tay WT, Ting D, Cheung CY, Sabanayagam C, Cheng CY, Wong TY, Yeo KK. BMJ Open Diabetes Res Care, 2021 Jul; 9(1).
- Gender Prediction for a Multiethnic Population via Deep Learning Across Different Retinal Fundus Photograph Fields: Retrospective Cross-sectional Study Betzler BK, Yang HHS, Thakur S, Yu M, Quek TC, Soh ZD, Lee G, Tham YC, Wong TY, Rim TH, Cheng CY. JMIR Med Inform, 2021 Aug 17; 9(8): e25165.
- White matter network damage mediates association between cerebrovascular disease and cognition Hilal S, Liu S, Wong TY, Vrooman H, Cheng CY, Venketasubramanian N, Chen CL, Zhou JH. J Cereb Blood Flow Metab, 2021 Aug; 41(8): 1858-1872.
- Prevalence and predictors of myopic macular degeneration among Asian adults: pooled analysis from the Asian Eye Epidemiology Consortium Wong YL, Zhu X, Tham YC, Yam JCS, Zhang K, Sabanayagam C, Lanca C, Zhang X, Han SY, He W, Susvar P, Trivedi M, Yuan N, Lambat S, Raman R, Song SJ, Wang YX, Bikbov MM, Nangia V, Chen LJ, Wong TY, Lamoureux EL, Pang CP, Cheng CY, Lu Y, Jonas JB, Saw SM, Asian Eye Epidemiology Consortium. Br J Ophthalmol, 2021 Aug; 105(8): 1140-1148.
- APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups Goyal S, Tanigawa Y, Zhang W, Chai JF, Almeida M, Sim X, Lerner M, Chainakul J, Ramiu JG, Seraphin C, Apple B, Vaughan A, Muniu J, Peralta J, Lehman DM, Ralhan S, Wander GS, Singh JR, Mehra NK, Sidorov E, Peyton MD, Blackett PR, Curran JE, Tai ES, van Dam R, Cheng CY, Duggirala R, Blangero J, Chambers JC, Sabanayagam C, Kooner JS, Rivas MA, Aston CE, Sanghera DK. Lipids Health Dis, 2021 Sep 21; 20(1): 113.
- Novel Serum and Urinary Metabolites Associated with Diabetic Retinopathy in Three Asian Cohorts Quek DQY, He F, Sultana R, Banu R, Chee ML, Nusinovici S, Thakur S, Qian C, Cheng CY, Wong TY, Sabanayagam C. Metabolites, 2021 Sep 9; 11(9).
- The Global Extent of Undetected Glaucoma in Adults: A Systematic Review and Meta-analysis Soh Z, Yu M, Betzler BK, Majithia S, Thakur S, Tham YC, Wong TY, Aung T, Friedman DS, Cheng CY. Ophthalmology, 2021 Oct; 128(10): 1393-1404.
- Visual Impairment, Major Eye Diseases and Mortality in a Multi-Ethnic Asian Population and a Meta-analysis of Prospective Studies Ng Yin Ling C, Seshasai S, Chee ML, He F, Tham YC, Cheng CY, Wong TY, Sabanayagam C. Am J Ophthalmol, 2021 Nov; 231: 88-100.
- Association between Body Mass Index and Chronic Kidney Disease in Asian Populations: A Participant-level Meta-Analysis Betzler BK, Sultana R, Banu R, Tham YC, Lim CC, Wang YX, Nangia V, Tai ES, Rim TH, Bikbov MM, Jonas JB, Cheng CY, Sabanayagam C. Maturitas, 2021 Dec; 154: 46-54.
- Deep Learning Approach for Automated Detection of Myopic Maculopathy and Pathologic Myopia in Fundus Images Du R, Xie S, Fang Y, Igarashi-Yokoi T, Moriyama M, Ogata S, Tsunoda T, Kamatani T, Yamamoto S, Cheng CY, Saw SM, Ting D, Wong TY, Ohno-Matsui K. Ophthalmol Retina, 2021 Dec; 5(12): 1235-1244.
- Application of machine learning techniques to understand ethnic differences and risk factors for incident chronic kidney disease in Asians Lim CC, He F, Li J, Tham YC, Tan CS, Cheng CY, Wong TY, Sabanayagam C. BMJ Open Diabetes Res Care, 2021 Dec; 9(2).
2020
- The prevalence and clinical associations of disproportionately enlarged subarachnoid space hydrocephalus (DESH), an imaging feature of idiopathic normal pressure hydrocephalus in community and memory clinic based Singaporean cohorts Akiba C, Gyanwali B, Villaraza S, Nakajima M, Miyajima M, Cheng CY, Wong TY, Venketasubramanian N, Hilal S, Chen C. J Neurol Sci, 2020 Jan 15; 408: 116510.
- Compensation of retinal nerve fibre layer thickness as assessed using optical coherence tomography based on anatomical confounders Chua J, Schwarzhans F, Nguyen DQ, Tham YC, Sia JT, Lim C, Mathijia S, Cheung C, Tin A, Fischer G, Cheng CY, Vass C, Schmetterer L. Br J Ophthalmol, 2020 Feb; 104(2): 282-290.
- Interethnic differences in neuroimaging markers and cognition in Asians, a population-based study Wong LCK, Wong MYZ, Tan CS, Vrooman H, Venketasubramanian N, Cheng CY, Chen C, Hilal S. Sci Rep, 2020 Feb 14; 10(1): 2655.
- Systemic medications and cortical cataract: the Singapore Epidemiology of Eye Diseases Study Dai W, Tham YC, Chee ML, Majithia S, Poh S, Tan AG, Tao Y, Wang JJ, Cheng CY. Br J Ophthalmol, 2020 Mar; 104(3): 330-335.
- Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error Fan Q, Pozarickij A, Tan NYQ, Guo X, Verhoeven VJM, Vitart V, Guggenheim JA, Miyake M, Tideman JWL, Khawaja AP, Zhang L, MacGregor S, Hohn R, Chen P, Biino G, Wedenoja J, Saffari SE, Tedja MS, Xie J, Lanca C, Wang YX, Sahebjada S, Mazur J, Mirshahi A, Martin NG, Yazar S, Pennell CE, Yap M, Haarman AEG, Enthoven CA, Polling J, Consortium for Refractive Error and Myopia (CREAM), UK Biobank Eye Vision Consortium, Hewitt AW, Jaddoe VWV, van Duijn CM, Hayward C, Polasek O, Tai ES, Yoshikatsu H, Hysi PG, Young TL, Tsujikawa A, Wang JJ, Mitchell P, Pfeiffer N, Parssinen O, Foster PJ, Fossarello M, Yip SP, Williams C, Hammond CJ, Jonas JB, He M, Mackey DA, Wong TY, Klaver CCW, Saw SM, Baird PN, Cheng CY. Commun Biol, 2020 Mar 19; 3(1): 133.
- Association of G6PD variants with hemoglobin A1c and impact on diabetes diagnosis in East Asian individuals Leong A, Lim VJY, Wang C, Chai JF, Dorajoo R, Heng CK, van Dam RM, Koh WP, Yuan JM, Jonas JB, Wang YX, Wei WB, Liu J, Reilly DF, Wong TY, Cheng CY, Sim X. BMJ Open Diabetes Res Care, 2020 Mar; 8(1).
- Cataract Surgery and the 6-year Incidence of Age-Related Macular Degeneration in a Multiethnic Asian Cohort Gan AT, Man RE, Cheung CMG, Kumari N, Fenwick EK, Sabanayagam C, Tham YC, Tan NY, Mitchell P, Wong TY, Cheng CY, Lamoureux EL. Asia Pac J Ophthalmol (Phila), 2020 Mar-Apr; 9(2): 130-136.
- Artificial Intelligence for Cataract Detection and Management Goh JHL, Lim ZW, Fang X, Anees A, Nusinovici S, Rim TH, Cheng CY, Tham YC. Asia Pac J Ophthalmol (Phila), 2020 Mar-Apr; 9(2): 88-95.
- High-Density Lipoprotein Cholesterol in Age-Related Ocular Diseases Betzler BK, Rim TH, Sabanayagam C, Cheung CMG, Cheng CY. Biomolecules, 2020 Apr 22; 10(4).
- Rates and Determinants of Eyecare Utilization and Eyeglass Affordability Among Individuals With Visual Impairment in a Multi-Ethnic Population-Based Study in Singapore Gupta P, Majithia S, Fenwick EK, Gan ATL, Tham YC, Poh S, Thakur S, Sabanayagam C, Wong TY, Cheng CY, Lamoureux EL. Transl Vis Sci Technol, 2020 Apr; 9(5): 11.
- Association Between Visual Impairment and Decline in Cognitive Function in a Multiethnic Asian Population Lim ZW, Chee ML, Soh ZD, Cheung N, Dai W, Sahil T, Tao Y, Majithia S, Sabanayagam C, Chen CL, Wong TY, Cheng CY, Tham YC. JAMA Netw Open, 2020 Apr 1; 3(4): e203560.
- Artificial Intelligence to Detect Papilledema from Ocular Fundus Photographs Milea D, Najjar RP, Zhubo J, Ting D, Vasseneix C, Xu X, Aghsaei Fard M, Fonseca P, Vanikieti K, Lagreze WA, La Morgia C, Cheung CY, Hamann S, Chiquet C, Sanda N, Yang H, Mejico LJ, Rougier MB, Kho R, Thi Ha Chau T, Singhal S, Gohier P, Clermont-Vignal C, Cheng CY, Jonas JB, Yu-Wai-Man P, Fraser CL, Chen JJ, Ambika S, Miller NR, Liu Y, Newman NJ, Wong TY, Biousse V, Bonsai Group. N Engl J Med, 2020 Apr 30; 382(18): 1687-1695.
- Association between Macular Thickness Profiles and Visual Function in Healthy Eyes: The Singapore Epidemiology of Eye Diseases (SEED) Study Poh S, Tham YC, Chee ML, Dai W, Majithia S, Soh ZD, Fenwick EK, Tao Y, Thakur S, Rim TH, Sabanayagam C, Cheng CY. Sci Rep, 2020 Apr 9; 10(1): 6142.
- Six-Year Changes in Myopic Macular Degeneration in Adults of the Singapore Epidemiology of Eye Diseases Study Wong YL, Sabanayagam C, Wong CW, Cheung YB, Man REK, Yeo AC, Cheung G, Chia A, Kuo A, Ang M, Ohno-Matsui K, Wong TY, Wang JJ, Cheng CY, Hoang QV, Lamoureux E, Saw SM. Invest Ophthalmol Vis Sci, 2020 Apr 9; 61(4): 14.
- Agreement in Measures of Macular Perfusion between Optical Coherence Tomography Angiography Machines Dai W, Chee ML, Majithia S, Teo CL, Thakur S, Cheung N, Rim TH, Tan GS, Sabanayagam C, Cheng CY, Tham YC. Sci Rep, 2020 May 20; 10(1): 8345.
- Singapore Chinese Eye Study: key findings from baseline examination and the rationale, methodology of the 6-year follow-up series Majithia S, Tham YC, Chee ML, Teo CL, Chee ML, Dai W, Kumari N, Lamoureux EL, Sabanayagam C, Wong TY, Cheng CY. Br J Ophthalmol, 2020 May; 104(5): 610-615.
- Logistic regression was as good as machine learning for predicting major chronic diseases Nusinovici S, Tham YC, Chak Yan MY, Wei Ting DS, Li J, Sabanayagam C, Wong TY, Cheng CY. J Clin Epidemiol, 2020 Jun; 122: 56-69.
- A deep learning algorithm to detect chronic kidney disease from retinal photographs in community-based populations Sabanayagam C, Xu D, Ting DSW, Nusinovici S, Banu R, Hamzah H, Lim C, Tham YC, Cheung CY, Tai ES, Wang YX, Jonas JB, Cheng CY, Lee ML, Hsu W, Wong TY. Lancet Digit Health, 2020 Jun; 2(6): e295-e302.
- Identification of type 2 diabetes loci in 433,540 East Asian individuals Spracklen CN, Horikoshi M, Kim YJ, Lin K, Bragg F, Moon S, Suzuki K, Tam CHT, Tabara Y, Kwak SH, Takeuchi F, Long J, Lim VJY, Chai JF, Chen CH, Nakatochi M, Yao J, Choi HS, Iyengar AK, Perrin HJ, Brotman SM, van de Bunt M, Gloyn AL, Below JE, Boehnke M, Bowden DW, Chambers JC, Mahajan A, McCarthy MI, Ng MCY, Petty LE, Zhang W, Morris AP, Adair LS, Akiyama M, Bian Z, Chan JCN, Chang LC, Chee ML, Chen YI, Chen YT, Chen Z, Chuang LM, Du S, Gordon-Larsen P, Gross M, Guo X, Guo Y, Han S, Howard AG, Huang W, Hung YJ, Hwang MY, Hwu CM, Ichihara S, Isono M, Jang HM, Jiang G, Jonas JB, Kamatani Y, Katsuya T, Kawaguchi T, Khor CC, Kohara K, Lee MS, Lee NR, Li L, Liu J, Luk AO, Lv J, Okada Y, Pereira MA, Sabanayagam C, Shi J, Shin DM, So WY, Takahashi A, Tomlinson B, Tsai FJ, van Dam RM, Xiang YB, Yamamoto K, Yamauchi T, Yoon K, Yu C, Yuan JM, Zhang L, Zheng W, Igase M, Cho YS, Rotter JI, Wang YX, Sheu WHH, Yokota M, Wu JY, Cheng CY, Wong TY, Shu XO, Kato N, Park KS, Tai ES, Matsuda F, Koh WP, Ma RCW, Maeda S, Millwood IY, Lee J, Kadowaki T, Walters RG, Kim BJ, Mohlke KL, Sim X. Nature, 2020 Jun; 582(7811): 240-245.
- Systemic hypertension associated retinal microvascular changes can be detected with optical coherence tomography angiography Sun C, Ladores C, Hong J, Nguyen DQ, Chua J, Ting D, Schmetterer L, Wong TY, Cheng CY, Tan ACS. Sci Rep, 2020 Jun 12; 10(1): 9580.
- Profile of retinal nerve fibre layer symmetry in a multiethnic Asian population: the Singapore Epidemiology of Eye Diseases study Tao Y, Tham YC, Chee ML, Majithia S, Thakur S, Soh ZD, Cheung CY, Sabanayagam C, Wong TY, Cheng CY. Br J Ophthalmol, 2020 Jun; 104(6): 836-841.
- Association of Cataract Surgery With Risk of Diabetic Retinopathy Among Asian Participants in the Singapore Epidemiology of Eye Diseases Study Tham YC, Liu L, Rim TH, Zhang L, Majithia S, Chee ML, Tan NYQ, Wong KH, Ting DSW, Sabanayagam C, Wang JJ, Mitchell P, Wong TY, Cheng CY. JAMA Netw Open, 2020 Jun 1; 3(6): e208035.
- Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson Hosoda Y, Miyake M, Meguro A, Tabara Y, Iwai S, Ueda-Arakawa N, Nakano E, Mori Y, Yoshikawa M, Nakanishi H, Khor CC, Saw SM, Yamada R, Matsuda F, Cheng CY, Mizuki N, Tsujikawa A, Yamashiro K, Nagahama Study Group. Commun Biol, 2020 Jul 31; 3(1): 410.
- Incidence, progression and risk factors of age-related cataract in Malays: The Singapore Malay Eye Study Tan AG, Tham YC, Chee ML, Mitchell P, Cumming RG, Sabanayagam C, Wong TY, Wang JJ, Cheng CY. Clin Exp Ophthalmol, 2020 Jul; 48(5): 580-592.
- Do we have enough ophthalmologists to manage vision-threatening diabetic retinopathy? A global perspective Teo ZL, Tham YC, Yu M, Cheng CY, Wong TY, Sabanayagam C. Eye (Lond), 2020 Jul; 34(7): 1255-1261.
- Big Data in Ophthalmology Cheng CY, Soh ZD, Majithia S, Thakur S, Rim TH, Tham YC, Wong TY. Asia Pac J Ophthalmol (Phila), 2020 Jul-Aug; 9(4): 291-298.
- Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study Chai X, Low KY, Tham YC, Chee ML, Thakur S, Zhang L, Tan NY, Khor CC, Aung T, Wong TY, Cheng CY. Invest Ophthalmol Vis Sci, 2020 Aug 3; 61(10): 37.
- Deep Learning for Automated Sorting of Retinal Photographs Rim TH, Soh ZD, Tham YC, Yang HHS, Lee G, Kim Y, Nusinovici S, Ting DSW, Wong TY, Cheng CY. Ophthalmol Retina, 2020 Aug; 4(8): 793-800.
- Profiles of Ganglion Cell-Inner Plexiform Layer Thickness in a Multi-Ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study Tham YC, Chee ML, Dai W, Lim ZW, Majithia S, Siantar R, Thakur S, Rim T, Cheung CY, Sabanayagam C, Aung T, Wong TY, Cheng CY. Ophthalmology, 2020 Aug; 127(8): 1064-1076.
- Decrease in Choroidal Vascularity Index of Haller’s layer in diabetic eyes precedes retinopathy Foo VHX, Gupta P, Nguyen QD, Chong CCY, Agrawal R, Cheng CY, Yanagi Y. BMJ Open Diabetes Res Care, 2020 Sep; 8(1).
- Using Uniocular Visual Acuity Substantially Underestimates the Impact of Visual Impairment on Quality of Life Compared with Binocular Visual Acuity Kidd Man RE, Liang Gan AT, Fenwick EK, Thakur S, Gupta P, Teo ZL, Cheng CY, Wong TY, Lamoureux EL.Ophthalmology, 2020 Sep; 127(9): 1145-1151.
- MRI of posterior eye shape and its associations with myopia and ethnicity Lim LS, Matsumura S, Htoon HM, Tian J, Lim SB, Sensaki S, Chen C, Hilal S, Wong TY, Cheng CY, Kuo A, Saw SM. Br J Ophthalmol, 2020 Sep; 104(9): 1239-1245.
- Statistical inference for decision curve analysis, with applications to cataract diagnosis Sande SZ, Li J, D’Agostino R, Yin Wong T, Cheng CY. Stat Med, 2020 Sep 30; 39(22): 2980-3002.
- Is kidney function associated with primary open-angle glaucoma? Findings from the Asian Eye Epidemiology Consortium Tham YC, Tao Y, Zhang L, Rim THT, Thakur S, Lim ZW, Chee ML, Bikbov MM, Kazakbaeva GM, Wang N, Cao K, Hao J, Nangia V, Panda-Jonas S, Wang YX, Wong IY, Chan JCH, Meng Q, Sabanayagam C, Wong TY, Jonas JB, Zhong H, Cheng CY, Asian Eye Epidemiology Consortium. Br J Ophthalmol, 2020 Sep; 104(9): 1298-1303.
- Diagnostic Ability of Individual Macular Layers by Spectral-Domain OCT in Different Stages of Glaucoma Chua J, Tan B, Ke M, Schwarzhans F, Vass C, Wong D, Nongpiur ME, Wei Chua MC, Yao X, Cheng CY, Aung T, Schmetterer L.Ophthalmol Glaucoma, 2020 Sep-Oct; 3(5): 314-326.
- Prevalence and Pattern of Geographic Atrophy in Asia: The Asian Eye Epidemiology Consortium Rim TH, Kawasaki R, Tham YC, Kang SW, Ruamviboonsuk P, Bikbov MM, Miyake M, Hao J, Fletcher A, Sasaki M, Nangia V, Sabanayagam C, Yu M, Fujiwara K, Thapa R, Wong IY, Kayama T, Chen SJ, Kuang TM, Yamashita H, Sundaresan P, Chan JC, van Rens G, Sonoda KH, Wang YX, Panda-Jonas S, Harada S, Kim R, Ganesan S, Raman R, Yamashiro K, Gilmanshin TR, Jenchitr W, Park KH, Gemmy Cheung CM, Wong TY, Wang N, Jonas JB, Chakravarthy U, Cheng CY, Yanagi Y, Asian Eye Epidemiology Consortium. Ophthalmology, 2020a Oct; 127(10): 1371-1381.
- Prediction of systemic biomarkers from retinal photographs: development and validation of deep-learning algorithms Rim TH, Lee G, Kim Y, Tham YC, Lee CJ, Baik SJ, Kim YA, Yu M, Deshmukh M, Lee BK, Park S, Kim HC, Sabayanagam C, Ting DSW, Wang YX, Jonas JB, Kim SS, Wong TY, Cheng CY. Lancet Digit Health, 2020b Oct; 2(10): e526-e536.
- Global assessment of arteriolar, venular and capillary changes in normal tension glaucoma Lin TPH, Wang YM, Ho K, Wong CYK, Chan PP, Wong MOM, Chan NCY, Tang F, Lam A, Leung DYL, Wong TY, Cheng CY, Cheung CY, Tham CC. Sci Rep, 2020 Nov 5; 10(1): 19222.
- Normative patterns and factors associated with presbyopia progression in a multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study Majithia S, Wong KH, Chee ML, Soh ZD, Thakur S, Fang XL, Teo ZL, Sabanayagam C, Tham YC, Cheng CY. Br J Ophthalmol, 2020 Nov; 104(11): 1591-1595.
- Genome-Wide Association for HbA1c in Malay Identified Deletion on SLC4A1 that Influences HbA1c Independent of Glycemia Chai JF, Kao SL, Wang C, Lim VJ, Khor IW, Dou J, Podgornaia AI, Chothani S, Cheng CY, Sabanayagam C, Wong TY, van Dam RM, Liu J, Reilly DF, Paterson AD, Sim X. J Clin Endocrinol Metab, 2020 Dec 1; 105(12).
- Association of common genetic variants with brain microbleeds: A genome-wide association study Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Jr., Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS, Alzheimer’s Disease Neuroimaging Initiative. Neurology, 2020 Dec 15; 95(24): e3331-e3343.
- Genome-Wide Association Study in Asians Identifies Novel Loci for High Myopia and Highlights a Nervous System Role in Its Pathogenesis Meguro A, Yamane T, Takeuchi M, Miyake M, Fan Q, Zhao W, Wang IJ, Mizuki Y, Yamada N, Nomura N, Tsujikawa A, Matsuda F, Hosoda Y, Saw SM, Cheng CY, Tsai TH, Yoshida M, Iijima Y, Teshigawara T, Okada E, Ota M, Inoko H, Mizuki N. Ophthalmology, 2020 Dec; 127(12): 1612-1624.
- Asian-specific vertical cup-to-disc ratio cut-off for glaucoma screening: An evidence-based recommendation from a multi-ethnic Asian population Soh ZD, Chee ML, Thakur S, Tham YC, Tao Y, Lim ZW, Mani B, Wong TT, Aung T, Cheng CY. Clin Exp Ophthalmol, 2020 Dec; 48(9): 1210-1218.
- Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract Yonova-Doing E, Zhao W, Igo RP, Jr., Wang C, Sundaresan P, Lee KE, Jun GR, Alves AC, Chai X, Chan ASY, Lee MC, Fong A, Tan AG, Khor CC, Chew EY, Hysi PG, Fan Q, Chua J, Chung J, Liao J, Colijn JM, Burdon KP, Fritsche LG, Swift MK, Hilmy MH, Chee ML, Tedja M, Bonnemaijer PWM, Gupta P, Tan QS, Li Z, Vithana EN, Ravindran RD, Chee SP, Shi Y, Liu W, Su X, Sim X, Shen Y, Wang YX, Li H, Tham YC, Teo YY, Aung T, Small KS, Mitchell P, Jonas JB, Wong TY, Fletcher AE, Klaver CCW, Klein BEK, Wang JJ, Iyengar SK, Hammond CJ, Cheng CY. Commun Biol, 2020 Dec 11; 3(1): 755.
- Hypertension, blood pressure control and diabetic retinopathy in a large population-based study Liu L, Quang ND, Banu R, Kumar H, Tham YC, Cheng CY, Wong TY, Sabanayagam C. PLoS One, 2020; 15(3): e0229665.
- MRI Markers of Mixed Pathology and Cognitive Impairment in Multiethnic Asians Tan CH, Hilal S, Xu X, Vrooman H, Cheng CY, Wong TY, Venketasubramanian N, Chen C. J Alzheimers Dis, 2020; 73(4): 1501-1509.
2019
- Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer’s Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Neurology. 2019 Jan 16;92(5):e486–503. doi: 10.1212/WNL.0000000000006851
- Association of Diabetes With Central Corneal Thickness Among a Multiethnic Asian Population Luo XY, Dai W, Chee ML, Tao Y, Chua J, Tan NYQ, Tham YC, Aung T, Wong TY, Cheng CY. JAMA Netw Open. 2019 Jan 4;2(1):e186647. doi: 10.1001/jamanetworkopen.2018.6647
- Inter-relationship between ageing, body mass index, diabetes, systemic blood pressure and intraocular pressure in Asians: 6-year longitudinal study Chua J, Chee ML, Chin CWL, Tham YC, Tan N, Lim SH, Aung T, Cheng CY, Wong TY, Schmetterer LBr J Ophthalmol. 2019 Feb;103(2):196-202. doi: 10.1136/bjophthalmol-2018-311897. Epub 2018 Apr 9
- Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control Pollack S, Igo RP Jr, Jensen RA, Christiansen M, Li X, Cheng CY, Ng MCY, Smith AV, Rossin EJ, Segrè AV, Davoudi S, Tan GS, Chen YI, Kuo JZ, Dimitrov LM, Stanwyck LK, Meng W, Hosseini SM, Imamura M, Nousome D, Kim J, Hai Y, Jia Y, Ahn J, Leong A, Shah K, Park KH, Guo X, Ipp E, Taylor KD, Adler SG, Sedor JR, Freedman BI; Family Investigation of Nephropathy and Diabetes-Eye Research Group, DCCT/EDIC Research Group; Lee IT, Sheu WH, Kubo M, Takahashi A, Hadjadj S, Marre M, Tregouet DA, Mckean-Cowdin R, Varma R, McCarthy MI, Groop L, Ahlqvist E, Lyssenko V, Agardh E, Morris A, Doney ASF, Colhoun HM, Toppila I, Sandholm N, Groop PH, Maeda S, Hanis CL, Penman A, Chen CJ, Hancock H, Mitchell P, Craig JE, Chew EY, Paterson AD, Grassi MA, Palmer C, Bowden DW, Yaspan BL, Siscovick D, Cotch MF, Wang JJ, Burdon KP, Wong TY, Klein BEK, Klein R, Rotter JI, Iyengar SK, Price AL, Sobrin L. Diabetes. 2019 Feb;68(2):441-456. doi: 10.2337/db18-0567. Epub 2018 Nov 28. Erratum in: Diabetes. 2020 Jun;69(6):1306
- Incidence and progression of diabetic retinopathy: a systematic review Sabanayagam C, Banu R, Chee ML, Lee R, Wang YX, Tan G, Jonas JB, Lamoureux EL, Cheng CY, Klein BEK, Mitchell P, Klein R, Cheung CMG, Wong TY. Lancet Diabetes Endocrinol. 2019 Feb;7(2):140-149. doi: 10.1016/S2213-8587(18)30128-1. Epub 2018 Jul 11
- U-Shaped Relationship between Serum Leptin Concentration and Cognitive Performance in Older Asian Adults Annweiler C, Duval GT, Cheng CY, Wong TY, Lamoureux EL, Milea D, Sabanayagam C. Nutrients. 2019 Mar 19;11(3):660. doi: 10.3390/nu11030660
- Association of Diabetic Retinopathy and Diabetic Kidney Disease With All-Cause and Cardiovascular Mortality in a Multiethnic Asian Population Sabanayagam C, Chee ML, Banu R, Cheng CY, Lim SC, Tai ES, Coffman T, Wong TY. JAMA Netw Open. 2019 Mar 1;2(3):e191540. doi: 10.1001/jamanetworkopen.2019.1540
- Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI, Lim E, Deng X, Guo X, Liu J, Lu Y, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Baker J, Chen G, Aschard H, Bartz TM, Ding J, Dorajoo R, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Zhao W, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Hung YJ, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lin KH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Prins B, Riaz M, Robino A, Said MA, Schupf N, Scott RA, Sofer T, Stancáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang TD, Wang Y, Ware EB, Wen W, Xiang YB, Yanek LR, Zhang W, Zhao JH, Adeyemo A, Afaq S, Amin N, Amini M, Arking DE, Arzumanyan Z, Aung T, Ballantyne C, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Broeckel U, Brown M, Cade BE, Campbell A, Canouil M, Charumathi S, Chen YI, Christensen K; COGENT-Kidney Consortium; Concas MP, Connell JM, de Las Fuentes L, de Silva HJ, de Vries PS, Doumatey A, Duan Q, Eaton CB, Eppinga RN, Faul JD, Floyd JS, Forouhi NG, Forrester T, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gharib SA, Gigante B, Giulianini F, Grabe HJ, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Ikram MA; EPIC-InterAct Consortium; Jia Y, Joehanes R, Johnson C, Jonas JB, Justice AE, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y, Liang J, Lin S, Liu CT, Liu J, Liu K, Loh M, Lohman KK, Louie T, Luzzi A, Mägi R, Mahajan A, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Morris AP, Murray AD, Nalls MA, Nauck M, Nelson CP, North KE, O’Connell JR, Palmer ND, Papanicolau GJ, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raitakari OT, Reiner AP, Renström F, Rice TK, Rich SS, Robinson JG, Rose LM, Rosendaal FR, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Tiemeier H, Turner ST, Uitterlinden AG; Understanding Society Scientific Group; van Heemst D, Waldenberger M, Wang H, Wang L, Wang L, Wei WB, Williams CA, Wilson G Sr, Wojczynski MK, Yao J, Young K, Yu C, Yuan JM, Zhou J, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Cooper RS, de Faire U, Deary IJ, Elliott P, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Juang JJ, Kamatani Y, Kammerer CM, Kato N, Kooner JS, Laakso M, Laurie CC, Lee IT, Lehtimäki T; Lifelines Cohort; Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Pereira AC, Rauramaa R, Redline S, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang JS, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zeggini E, Zheng W, Bouchard C, Evans MK, Gudnason V, Kardia SLR, Liu Y, Psaty BM, Ridker PM, van Dam RM, Mook-Kanamori DO, Fornage M, Province MA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Franceschini N, Rotter JI, Zhu X, Bierut LJ, Gauderman WJ, Rice K, Munroe PB, Morrison AC, Rao DC, Rotimi CN, Cupples LA. Nat Genet. 2019 Apr;51(4):636-648. doi: 10.1038/s41588-019-0378-y. Epub 2019 Mar 29
- Retinal Nerve Fiber Layer Thickness in a Multiethnic Normal Asian Population: The Singapore Epidemiology of Eye Diseases Study Ho H, Tham YC, Chee ML, Shi Y, Tan NYQ, Wong KH, Majithia S, Cheung CY, Aung T, Wong TY, Cheng CY. Ophthalmology. 2019 May;126(5):702-711. doi: 10.1016/j.ophtha.2018.11.031. Epub 2018 Dec 4
- Relationship Between Sleep and Symptoms of Tear Dysfunction in Singapore Malays and Indians Lim EWL, Chee ML, Sabanayagam C, Majithia S, Tao Y, Wong TY, Cheng CY, Tong L. Invest Ophthalmol Vis Sci. 2019 May 1;60(6):1889-1897. doi: 10.1167/iovs.19-26810
- Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions de Vries PS, Brown MR, Bentley AR, Sung YJ, Winkler TW, Ntalla I, Schwander K, Kraja AT, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Huffman JE, Musani SK, Li C, Feitosa MF, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Deng X, Dorajoo R, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Evangelou E, Graff M, Alver M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Goel A, Hagemeijer Y, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Lee JH, Luan J, Lyytikäinen LP, Matoba N, Nolte IM, Pietzner M, Riaz M, Said MA, Scott RA, Sofer T, Stančáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Wang Y, Ware EB, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Ballantyne C, Boerwinkle E, Broeckel U, Campbell A, Canouil M, Charumathi S, Chen YI, Connell JM, de Faire U, de Las Fuentes L, de Mutsert R, de Silva HJ, Ding J, Dominiczak AF, Duan Q, Eaton CB, Eppinga RN, Faul JD, Fisher V, Forrester T, Franco OH, Friedlander Y, Ghanbari M, Giulianini F, Grabe HJ, Grove ML, Gu CC, Harris TB, Heikkinen S, Heng CK, Hirata M, Hixson JE, Howard BV, Ikram MA; InterAct Consortium; Jacobs DR, Johnson C, Jonas JB, Kammerer CM, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Koistinen HA, Kolcic I, Kooperberg C, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lemaitre RN, Li Y, Liang J, Liu J, Liu K, Loh M, Louie T, Mägi R, Manichaikul AW, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Mosley TH, Mukamal KJ, Nalls MA, Nauck M, Nelson CP, Sotoodehnia N, O’Connell JR, Palmer ND, Pazoki R, Pedersen NL, Peters A, Peyser PA, Polasek O, Poulter N, Raffel LJ, Raitakari OT, Reiner AP, Rice TK, Rich SS, Robino A, Robinson JG, Rose LM, Rudan I, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Shi Y, Sidney S, Sims M, Smith BH, Smith JA, Snieder H, Starr JM, Strauch K, Tan N, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, van Heemst D, Vuckovic D, Waldenberger M, Wang L, Wang Y, Wang Z, Wei WB, Williams C, Wilson G, Wojczynski MK, Yao J, Yu B, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Deary IJ, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Kamatani Y, Kato N, Kooner JS, Laakso M, Leander K, Lehtimäki T; Lifelines Cohort, Groningen, The Netherlands (Lifelines Cohort Study); Magnusson PKE, Penninx B, Pereira AC, Rauramaa R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wang YX, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Zheng W, Elliott P, North KE, Bouchard C, Evans MK, Gudnason V, Liu CT, Liu Y, Psaty BM, Ridker PM, van Dam RM, Kardia SLR, Zhu X, Rotimi CN, Mook-Kanamori DO, Fornage M, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Liu J, Rotter JI, Gauderman WJ, Province MA, Munroe PB, Rice K, Chasman DI, Cupples LA, Rao DC, Morrison AC. Am J Epidemiol. 2019 Jun 1;188(6):1033-1054. doi: 10.1093/aje/kwz005
- Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, Chen S, Contreras-Cubas C, Córdova E, Correa A, Cortes M, DeFronzo RA, Dolan L, Drews KL, Elliott A, Floyd JS, Gabriel S, Garay-Sevilla ME, García-Ortiz H, Gross M, Han S, Heard-Costa NL, Jackson AU, Jørgensen ME, Kang HM, Kelsey M, Kim BJ, Koistinen HA, Kuusisto J, Leader JB, Linneberg A, Liu CT, Liu J, Lyssenko V, Manning AK, Marcketta A, Malacara-Hernandez JM, Martínez-Hernández A, Matsuo K, Mayer-Davis E, Mendoza-Caamal E, Mohlke KL, Morrison AC, Ndungu A, Ng MCY, O’Dushlaine C, Payne AJ, Pihoker C; Broad Genomics Platform; Post WS, Preuss M, Psaty BM, Vasan RS, Rayner NW, Reiner AP, Revilla-Monsalve C, Robertson NR, Santoro N, Schurmann C, So WY, Soberón X, Stringham HM, Strom TM, Tam CHT, Thameem F, Tomlinson B, Torres JM, Tracy RP, van Dam RM, Vujkovic M, Wang S, Welch RP, Witte DR, Wong TY, Atzmon G, Barzilai N, Blangero J, Bonnycastle LL, Bowden DW, Chambers JC, Chan E, Cheng CY, Cho YS, Collins FS, de Vries PS, Duggirala R, Glaser B, Gonzalez C, Gonzalez ME, Groop L, Kooner JS, Kwak SH, Laakso M, Lehman DM, Nilsson P, Spector TD, Tai ES, Tuomi T, Tuomilehto J, Wilson JG, Aguilar-Salinas CA, Bottinger E, Burke B, Carey DJ, Chan JCN, Dupuis J, Frossard P, Heckbert SR, Hwang MY, Kim YJ, Kirchner HL, Lee JY, Lee J, Loos RJF, Ma RCW, Morris AD, O’Donnell CJ, Palmer CNA, Pankow J, Park KS, Rasheed A, Saleheen D, Sim X, Small KS, Teo YY, Haiman C, Hanis CL, Henderson BE, Orozco L, Tusié-Luna T, Dewey FE, Baras A, Gieger C, Meitinger T, Strauch K, Lange L, Grarup N, Hansen T, Pedersen O, Zeitler P, Dabelea D, Abecasis G, Bell GI, Cox NJ, Seielstad M, Sladek R, Meigs JB, Rich SS, Rotter JI; DiscovEHR Collaboration; CHARGE; LuCamp; ProDiGY; GoT2D; ESP; SIGMA-T2D; T2D-GENES; AMP-T2D-GENES; Altshuler D, Burtt NP, Scott LJ, Morris AP, Florez JC, McCarthy MI, Boehnke M. Nature. 2019 Jun;570(7759):71-76. doi: 10.1038/s41586-019-1231-2. Epub 2019 May 22
- The Informant AD8 Can Discriminate Patients with Dementia From Healthy Control Participants in an Asian Older Cohort Kan CN, Zhang L, Cheng CY, Wong TY, Venketasubramanian N, Chen CL, Xu X. J Am Med Dir Assoc. 2019 Jun;20(6):775-779. doi: 10.1016/j.jamda.2018.11.023. Epub 2019 Jan 17
- The Effect of Gender on Visual Field Sensitivity: The Singapore Chinese Eye Study Tan NYQ, Tham YC, Koh V, Cheung CY, Aung T, Wong TY, Cheng CY. Ophthalmic Epidemiol. 2019 Jun;26(3):183-188. doi: 10.1080/09286586.2019.1568505. Epub 2019 Jan 23
- A catalog of genetic loci associated with kidney function from analyses of a million individuals Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF, Gorski M, Tin A, Wang L, Chu AY, Hoppmann A, Kirsten H, Giri A, Chai JF, Sveinbjornsson G, Tayo BO, Nutile T, Fuchsberger C, Marten J, Cocca M, Ghasemi S, Xu Y, Horn K, Noce D, van der Most PJ, Sedaghat S, Yu Z, Akiyama M, Afaq S, Ahluwalia TS, Almgren P, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boehnke M, Boerwinkle E, Boissel M, Bottinger EP, Boutin TS, Brenner H, Brumat M, Burkhardt R, Butterworth AS, Campana E, Campbell A, Campbell H, Canouil M, Carroll RJ, Catamo E, Chambers JC, Chee ML, Chee ML, Chen X, Cheng CY, Cheng Y, Christensen K, Cifkova R, Ciullo M, Concas MP, Cook JP, Coresh J, Corre T, Sala CF, Cusi D, Danesh J, Daw EW, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Delgado G, Demirkan A, Di Angelantonio E, Dittrich K, Divers J, Dorajoo R, Eckardt KU, Ehret G, Elliott P, Endlich K, Evans MK, Felix JF, Foo VHX, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Friedlander Y, Froguel P, Gansevoort RT, Gao H, Gasparini P, Gaziano JM, Giedraitis V, Gieger C, Girotto G, Giulianini F, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V, Haller T, Hamet P, Harris TB, Hartman CA, Hayward C, Hellwege JN, Heng CK, Hicks AA, Hofer E, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Indridason OS, Ingelsson E, Ising M, Jaddoe VWV, Jakobsdottir J, Jonas JB, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kammerer CM, Kanai M, Kastarinen M, Kerr SM, Khor CC, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Kraja AT, Krajcoviechova A, Kramer H, Krämer BK, Kronenberg F, Kubo M, Kühnel B, Kuokkanen M, Kuusisto J, La Bianca M, Laakso M, Lange LA, Langefeld CD, Lee JJ, Lehne B, Lehtimäki T, Lieb W; Lifelines Cohort Study; Lim SC, Lind L, Lindgren CM, Liu J, Liu J, Loeffler M, Loos RJF, Lucae S, Lukas MA, Lyytikäinen LP, Mägi R, Magnusson PKE, Mahajan A, Martin NG, Martins J, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Melander O, Metspalu A, Mikaelsdottir EK, Milaneschi Y, Miliku K, Mishra PP; V. A. Million Veteran Program; Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Mychaleckyj JC, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O’Connell J, O’Donoghue ML, Olafsson I, Oldehinkel AJ, Orho-Melander M, Ouwehand WH, Padmanabhan S, Palmer ND, Palsson R, Penninx BWJH, Perls T, Perola M, Pirastu M, Pirastu N, Pistis G, Podgornaia AI, Polasek O, Ponte B, Porteous DJ, Poulain T, Pramstaller PP, Preuss MH, Prins BP, Province MA, Rabelink TJ, Raffield LM, Raitakari OT, Reilly DF, Rettig R, Rheinberger M, Rice KM, Ridker PM, Rivadeneira F, Rizzi F, Roberts DJ, Robino A, Rossing P, Rudan I, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Sabanayagam C, Salomaa V, Salvi E, Saum KU, Schmidt H, Schmidt R, Schöttker B, Schulz CA, Schupf N, Shaffer CM, Shi Y, Smith AV, Smith BH, Soranzo N, Spracklen CN, Strauch K, Stringham HM, Stumvoll M, Svensson PO, Szymczak S, Tai ES, Tajuddin SM, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorleifsson G, Toniolo D, Tönjes A, Tremblay J, Tzoulaki I, Uitterlinden AG, Vaccargiu S, van Dam RM, van der Harst P, van Duijn CM, Velez Edward DR, Verweij N, Vogelezang S, Völker U, Vollenweider P, Waeber G, Waldenberger M, Wallentin L, Wang YX, Wang C, Waterworth DM, Bin Wei W, White H, Whitfield JB, Wild SH, Wilson JF, Wojczynski MK, Wong C, Wong TY, Xu L, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang W, Zonderman AB, Rotter JI, Bochud M, Psaty BM, Vitart V, Wilson JG, Dehghan A, Parsa A, Chasman DI, Ho K, Morris AP, Devuyst O, Akilesh S, Pendergrass SA, Sim X, Böger CA, Okada Y, Edwards TL, Snieder H, Stefansson K, Hung AM, Heid IM, Scholz M, Teumer A, Köttgen A, Pattaro C. Nat Genet. 2019 Jun;51(6):957-972. doi: 10.1038/s41588-019-0407-x. Epub 2019 May 31
- Racial differences and determinants of macular thickness profiles in multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study Wong KH, Tham YC, Nguyen DQ, Dai W, Tan NYQ, Mathijia S, Neelam K, Cheung CY, Sabanayagam C, Schmetterer L, Wong TY, Cheng CY. Br J Ophthalmol. 2019 Jul;103(7):894-899. doi: 10.1136/bjophthalmol-2018-312447. Epub 2018 Aug 10
- A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR, Guo X, Schwander K, Manning AK, Brown MR, Aschard H, Feitosa MF, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Kilpeläinen TO, Richard MA, Aslibekyan S, Bartz TM, Dorajoo R, Li C, Liu Y, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, He M, Horimoto ARVR, Hsu FC, Jackson AU, Kammerer CM, Kasturiratne A, Komulainen P, Kühnel B, Leander K, Lee WJ, Lin KH, Luan J, Lyytikäinen LP, McKenzie CA, Nelson CP, Noordam R, Scott RA, Sheu WHH, Stančáková A, Takeuchi F, van der Most PJ, Varga TV, Waken RJ, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking DE, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cade B, Campbell A, Canouil M, Chakravarti A, Cocca M, Collins FS, Connell JM, de Mutsert R, de Silva HJ, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Forouhi NG, Franco OH, Friedlander Y, Gao H, Gigante B, Gu CC, Gupta P, Hagenaars SP, Harris TB, He J, Heikkinen S, Heng CK, Hofman A, Howard BV, Hunt SC, Irvin MR, Jia Y, Katsuya T, Kaufman J, Kerrison ND, Khor CC, Koh WP, Koistinen HA, Kooperberg CB, Krieger JE, Kubo M, Kutalik Z, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lee JH, Lehne B, Levy D, Lewis CE, Li Y; Lifelines Cohort Study; Lim SH, Liu CT, Liu J, Liu J, Liu Y, Loh M, Lohman KK, Louie T, Mägi R, Matsuda K, Meitinger T, Metspalu A, Milani L, Momozawa Y, Mosley TH Jr, Nalls MA, Nasri U, O’Connell JR, Ogunniyi A, Palmas WR, Palmer ND, Pankow JS, Pedersen NL, Peters A, Peyser PA, Polasek O, Porteous D, Raitakari OT, Renström F, Rice TK, Ridker PM, Robino A, Robinson JG, Rose LM, Rudan I, Sabanayagam C, Salako BL, Sandow K, Schmidt CO, Schreiner PJ, Scott WR, Sever P, Sims M, Sitlani CM, Smith BH, Smith JA, Snieder H, Starr JM, Strauch K, Tang H, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, Waldenberger M, Wang L, Wang YX, Wei WB, Wilson G, Wojczynski MK, Xiang YB, Yao J, Yuan JM, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Chen YI, Weir DR, de Faire U, Deary IJ, Esko T, Farrall M, Forrester T, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Hung YJ, Jonas JB, Kato N, Kooner JS, Laakso M, Lehtimäki T, Liang KW, Magnusson PKE, Oldehinkel AJ, Pereira AC, Perls T, Rauramaa R, Redline S, Rettig R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Wickremasinghe AR, Wu T, Kamatani Y, Laurie CC, Bouchard C, Cooper RS, Evans MK, Gudnason V, Hixson J, Kardia SLR, Kritchevsky SB, Psaty BM, van Dam RM, Arnett DK, Mook-Kanamori DO, Fornage M, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Loos RJF, Reiner AP, Rotimi CN, Bierut LJ, Zhu X, Cupples LA, Province MA, Rotter JI, Franks PW, Rice K, Elliott P, Caulfield MJ, Gauderman WJ, Munroe PB, Rao DC, Morrison AC. Hum Mol Genet. 2019 Aug 1;28(15):2615-2633. doi: 10.1093/hmg/ddz070
- Variation of Peripapillary Scleral Shape With Age Tun TA, Wang X, Baskaran M, Nongpiur ME, Tham YC, Perera SA, Strouthidis NG, Aung T, Cheng CY, Girard MJA. Invest Ophthalmol Vis Sci, 2019 Aug 1; 60(10): 3275-3282.
- Beyond vision loss: the independent impact of diabetic retinopathy on vision-related quality of life in a Chinese Singaporean population Fenwick EK, Man REK, Gan ATL, Kumari N, Wong C, Aravindhan A, Gupta P, Wang JJ, Mitchell P, Wong TY, Cheng CY, Lamoureux EL. Br J Ophthalmol, 2019 Sep; 103(9): 1314-1319.
- A.Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, Giri A, Sieber KB, Qiu C, Kirsten H, Tin A, Chu AY, Bansal N, Feitosa MF, Wang L, Chai JF, Cocca M, Fuchsberger C, Gorski M, Hoppmann A, Horn K, Li M, Marten J, Noce D, Nutile T, Sedaghat S, Sveinbjornsson G, Tayo BO, van der Most PJ, Xu Y, Yu Z, Gerstner L, Arnlov J, Bakker SJL, Baptista D, Biggs ML, Boerwinkle E, Brenner H, Burkhardt R, Carroll RJ, Chee ML, Chee ML, Chen M, Cheng CY, Cook JP, Coresh J, Corre T, Danesh J, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Dittrich K, Divers J, Eckardt KU, Ehret G, Endlich K, Felix JF, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Gansevoort RT, Giedraitis V, Gogele M, Grundner-Culemann F, Gudbjartsson DF, Gudnason V, Hamet P, Harris TB, Hicks AA, Holm H, Foo VHX, Hwang SJ, Ikram MA, Ingelsson E, Jaddoe VWV, Jakobsdottir J, Josyula NS, Jung B, Kahonen M, Khor CC, Kiess W, Koenig W, Korner A, Kovacs P, Kramer H, Kramer BK, Kronenberg F, Lange LA, Langefeld CD, Lee JJ, Lehtimaki T, Lieb W, Lim SC, Lind L, Lindgren CM, Liu J, Loeffler M, Lyytikainen LP, Mahajan A, Maranville JC, Mascalzoni D, McMullen B, Meisinger C, Meitinger T, Miliku K, Mook-Kanamori DO, Muller-Nurasyid M, Mychaleckyj JC, Nauck M, Nikus K, Ning B, Noordam R, Connell JO, Olafsson I, Palmer ND, Peters A, Podgornaia AI, Ponte B, Poulain T, Pramstaller PP, Rabelink TJ, Raffield LM, Reilly DF, Rettig R, Rheinberger M, Rice KM, Rivadeneira F, Runz H, Ryan KA, Sabanayagam C, Saum KU, Schottker B, Shaffer CM, Shi Y, Smith AV, Strauch K, Stumvoll M, Sun BB, Szymczak S, Tai ES, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorsteinsdottir U, Tonjes A, Tremblay J, Uitterlinden AG, van der Harst P, Verweij N, Vogelezang S, Volker U, Waldenberger M, Wang C, Wilson OD, Wong C, Wong TY, Yang Q, Yasuda M, Akilesh S, Bochud M, Boger CA, Devuyst O, Edwards TL, Ho K, Morris AP, Parsa A, Pendergrass SA, Psaty BM, Rotter JI, Stefansson K, Wilson JG, Susztak K, Snieder H, Heid IM, Scholz M, Butterworth AS, Hung AM, Pattaro C, Kottgen. Nat Commun, 2019 Sep 11; 10(1): 4130.
- Additive effect of cerebral atrophy on cognition in dementia-free elderly with cerebrovascular disease Xu X, Phua A, Collinson SL, Hilal S, Ikram MK, Wong TY, Cheng CY, Venketasubramanian N, Chen C. Stroke Vasc Neurol, 2019 Sep; 4(3): 135-140.
- Associations of autozygosity with a broad range of human phenotypes Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, Zhang W, Medina-Gomez C, Karlsson R, Bao Y, Bartz TM, Baumbach C, Biino G, Bixley MJ, Brumat M, Chai JF, Corre T, Cousminer DL, Dekker AM, Eccles DA, van Eijk KR, Fuchsberger C, Gao H, Germain M, Gordon SD, de Haan HG, Harris SE, Hofer E, Huerta-Chagoya A, Igartua C, Jansen IE, Jia Y, Kacprowski T, Karlsson T, Kleber ME, Li SA, Li-Gao R, Mahajan A, Matsuda K, Meidtner K, Meng W, Montasser ME, van der Most PJ, Munz M, Nutile T, Palviainen T, Prasad G, Prasad RB, Priyanka TDS, Rizzi F, Salvi E, Sapkota BR, Shriner D, Skotte L, Smart MC, Smith AV, van der Spek A, Spracklen CN, Strawbridge RJ, Tajuddin SM, Trompet S, Turman C, Verweij N, Viberti C, Wang L, Warren HR, Wootton RE, Yanek LR, Yao J, Yousri NA, Zhao W, Adeyemo AA, Afaq S, Aguilar-Salinas CA, Akiyama M, Albert ML, Allison MA, Alver M, Aung T, Azizi F, Bentley AR, Boeing H, Boerwinkle E, Borja JB, de Borst GJ, Bottinger EP, Broer L, Campbell H, Chanock S, Chee ML, Chen G, Chen YI, Chen Z, Chiu YF, Cocca M, Collins FS, Concas MP, Corley J, Cugliari G, van Dam RM, Damulina A, Daneshpour MS, Day FR, Delgado GE, Dhana K, Doney ASF, Dorr M, Doumatey AP, Dzimiri N, Ebenesersdottir SS, Elliott J, Elliott P, Ewert R, Felix JF, Fischer K, Freedman BI, Girotto G, Goel A, Gogele M, Goodarzi MO, Graff M, Granot-Hershkovitz E, Grodstein F, Guarrera S, Gudbjartsson DF, Guity K, Gunnarsson B, Guo Y, Hagenaars SP, Haiman CA, Halevy A, Harris TB, Hedayati M, van Heel DA, Hirata M, Hofer I, Hsiung CA, Huang J, Hung YJ, Ikram MA, Jagadeesan A, Jousilahti P, Kamatani Y, Kanai M, Kerrison ND, Kessler T, Khaw KT, Khor CC, de Kleijn DPV, Koh WP, Kolcic I, Kraft P, Kramer BK, Kutalik Z, Kuusisto J, Langenberg C, Launer LJ, Lawlor DA, Lee IT, Lee WJ, Lerch MM, Li L, Liu J, Loh M, London SJ, Loomis S, Lu Y, Luan J, Magi R, Manichaikul AW, Manunta P, Masson G, Matoba N, Mei XW, Meisinger C, Meitinger T, Mezzavilla M, Milani L, Millwood IY, Momozawa Y, Moore A, Morange PE, Moreno-Macias H, Mori TA, Morrison AC, Muka T, Murakami Y, Murray AD, de Mutsert R, Mychaleckyj JC, Nalls MA, Nauck M, Neville MJ, Nolte IM, Ong KK, Orozco L, Padmanabhan S, Palsson G, Pankow JS, Pattaro C, Pattie A, Polasek O, Poulter N, Pramstaller PP, Quintana-Murci L, Raikkonen K, Ralhan S, Rao DC, van Rheenen W, Rich SS, Ridker PM, Rietveld CA, Robino A, van Rooij FJA, Ruggiero D, Saba Y, Sabanayagam C, Sabater-Lleal M, Sala CF, Salomaa V, Sandow K, Schmidt H, Scott LJ, Scott WR, Sedaghati-Khayat B, Sennblad B, van Setten J, Sever PJ, Sheu WH, Shi Y, Shrestha S, Shukla SR, Sigurdsson JK, Sikka TT, Singh JR, Smith BH, Stancakova A, Stanton A, Starr JM, Stefansdottir L, Straker L, Sulem P, Sveinbjornsson G, Swertz MA, Taylor AM, Taylor KD, Terzikhan N, Tham YC, Thorleifsson G, Thorsteinsdottir U, Tillander A, Tracy RP, Tusie-Luna T, Tzoulaki I, Vaccargiu S, Vangipurapu J, Veldink JH, Vitart V, Volker U, Vuoksimaa E, Wakil SM, Waldenberger M, Wander GS, Wang YX, Wareham NJ, Wild S, Yajnik CS, Yuan JM, Zeng L, Zhang L, Zhou J, Amin N, Asselbergs FW, Bakker SJL, Becker DM, Lehne B, Bennett DA, van den Berg LH, Berndt SI, Bharadwaj D, Bielak LF, Bochud M, Boehnke M, Bouchard C, Bradfield JP, Brody JA, Campbell A, Carmi S, Caulfield MJ, Cesarini D, Chambers JC, Chandak GR, Cheng CY, Ciullo M, Cornelis M, Cusi D, Smith GD, Deary IJ, Dorajoo R, van Duijn CM, Ellinghaus D, Erdmann J, Eriksson JG, Evangelou E, Evans MK, Faul JD, Feenstra B, Feitosa M, Foisy S, Franke A, Friedlander Y, Gasparini P, Gieger C, Gonzalez C, Goyette P, Grant SFA, Griffiths LR, Groop L, Gudnason V, Gyllensten U, Hakonarson H, Hamsten A, van der Harst P, Heng CK, Hicks AA, Hochner H, Huikuri H, Hunt SC, Jaddoe VWV, De Jager PL, Johannesson M, Johansson A, Jonas JB, Jukema JW, Junttila J, Kaprio J, Kardia SLR, Karpe F, Kumari M, Laakso M, van der Laan SW, Lahti J, Laudes M, Lea RA, Lieb W, Lumley T, Martin NG, Marz W, Matullo G, McCarthy MI, Medland SE, Merriman TR, Metspalu A, Meyer BF, Mohlke KL, Montgomery GW, Mook-Kanamori D, Munroe PB, North KE, Nyholt DR, O’Connell J R, Ober C, Oldehinkel AJ, Palmas W, Palmer C, Pasterkamp GG, Patin E, Pennell CE, Perusse L, Peyser PA, Pirastu M, Polderman TJC, Porteous DJ, Posthuma D, Psaty BM, Rioux JD, Rivadeneira F, Rotimi C, Rotter JI, Rudan I, Den Ruijter HM, Sanghera DK, Sattar N, Schmidt R, Schulze MB, Schunkert H, Scott RA, Shuldiner AR, Sim X, Small N, Smith JA, Sotoodehnia N, Tai ES, Teumer A, Timpson NJ, Toniolo D, Tregouet DA, Tuomi T, Vollenweider P, Wang CA, Weir DR, Whitfield JB, Wijmenga C, Wong TY, Wright J, Yang J, Yu L, Zemel BS, Zonderman AB, Perola M, Magnusson PKE, Uitterlinden AG, Kooner JS, Chasman DI, Loos RJF, Franceschini N, Franke L, Haley CS, Hayward C, Walters RG, Perry JRB, Esko T, Helgason A, Stefansson K, Joshi PK, Kubo M, Wilson JF. Nat Commun, 2019 Oct 31; 10(1): 4957.
- Normative pattern and determinants of outer retinal thickness in an Asian population: the Singapore Epidemiology of Eye Diseases Study Dai W, Tham YC, Chee ML, Majithia S, Tan NYQ, Wong KH, Neelam K, Cheung N, Sabanayagam C, Cheung CY, Wong TY, Cheng CY. Br J Ophthalmol, 2019 Oct; 103(10): 1406-1412.
- VIMCO: variational inference for multiple correlated outcomes in genome-wide association studies Shi X, Jiao Y, Yang Y, Cheng CY, Yang C, Lin X, Liu J. Bioinformatics, 2019 Oct 1; 35(19): 3693-3700.
- Patterns and Risk Factor Profiles of Visual Loss in a Multiethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study Wong TY, Tham YC, Sabanayagam C, Cheng CY. Am J Ophthalmol, 2019 Oct; 206: 48-73.
- Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore Wu D, Dou J, Chai X, Bellis C, Wilm A, Shih CC, Soon WWJ, Bertin N, Lin CB, Khor CC, DeGiorgio M, Cheng S, Bao L, Karnani N, Hwang WYK, Davila S, Tan P, Shabbir A, Moh A, Tan EK, Foo JN, Goh LL, Leong KP, Foo RSY, Lam CSP, Richards AM, Cheng CY, Aung T, Wong TY, Ng HH, Sg K. Consortium, Liu J, Wang C. Cell, 2019 Oct 17; 179(3): 736-749 e715.
- Association between diabetic retinopathy and incident cognitive impairment Gupta P, Gan ATL, Man REK, Fenwick EK, Sabanayagam C, Mitchell P, Cheung CY, Cheung N, Wong TY, Cheng CY, Lamoureux EL. Br J Ophthalmol, 2019 Nov; 103(11): 1605-1609.
- Genetic architecture of subcortical brain structures in 38,851 individuals Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivieres S, Arias-Vasquez A, Chauhan G, Athanasiu L, Renteria ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santianez R, Kraemer B, Haberg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, Putz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx B, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, Samann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Valdes Hernandez MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR, Jr., Schofield PR, Muhleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, Jonsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT, Jr., Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lemaitre H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, Muller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, Volzke H, Wright MJ, van ‘t Ent D, Nothen MM, Ophoff RA, Buitelaar JK, Fernandez G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA. Nat Genet, 2019 Nov; 51(11): 1624-1636.
- Age-related changes of individual macular retinal layers among Asians Chua J, Tham YC, Tan B, Devarajan K, Schwarzhans F, Gan A, Wong D, Cheung CY, Majithia S, Thakur S, Fischer G, Vass C, Cheng CY, Schmetterer L. Sci Rep, 2019 Dec 30; 9(1): 20352.
- Six-year incidence and progression of diabetic retinopathy in Indian adults: the Singapore Indian Eye study Kumari N, Bhargava M, Nguyen DQ, Gan ATL, Tan G, Cheung N, Tan N, Wong C, Wang JJ, Mitchell P, Lamoureux EL, Cheng CY, Wong TY, Sabanayagam C. Br J Ophthalmol, 2019 Dec; 103(12): 1732-1739.
- Prevalence, determinants and association of unawareness of diabetes, hypertension and hypercholesterolemia with poor disease control in a multi-ethnic Asian population without cardiovascular disease Man REK, Gan AHW, Fenwick EK, Gan ATL, Gupta P, Sabanayagam C, Tan N, Wong KH, Wong TY, Cheng CY, Lamoureux EL. Popul Health Metr, 2019a Dec 5; 17(1): 17.
- Is Myopia Associated with the Incidence and Progression of Diabetic Retinopathy? Man REK, Gan ATL, Gupta P, Fenwick EK, Sabanayagam C, Tan NYQ, Mitchell P, Wong TY, Cheng CY, Lamoureux EL. Am J Ophthalmol, 2019b Dec; 208: 226-233.
- Integration of Genetic and Biometric Risk Factors for Detection of Primary Angle Closure Glaucoma Nongpiur ME, Khor CC, Cheng CY, Husain R, Boey PY, Chew A, Ho CL, Wong TT, Perera S, Wong TY, Vithana EN, Aung T. Am J Ophthalmol, 2019 Dec; 208: 160-165.
- Multi-trait genome-wide association study identifies new loci associated with optic disc parameters Bonnemaijer PWM, Leeuwen EMV, Iglesias AI, Gharahkhani P, Vitart V, Khawaja AP, Simcoe M, Hohn R, Cree AJ, Igo RP, International Glaucoma Genetics Consortium, Neighborhood Consortium, U.K. Biobank Eye Vision Consortium, Gerhold-Ay A, Nickels S, Wilson JF, Hayward C, Boutin TS, Polasek O, Aung T, Khor CC, Amin N, Lotery AJ, Wiggs JL, Cheng CY, Hysi PG, Hammond CJ, Thiadens A, MacGregor S, Klaver CCW, Duijn CMV. Commun Biol, 2019; 2: 435.
- Cerebral Small Vessel Disease and Enlarged Perivascular Spaces-Data From Memory Clinic and Population-Based Settings Gyanwali B, Vrooman H, Venketasubramanian N, Wong TY, Cheng CY, Chen C, Hilal S. Front Neurol, 2019; 10: 669.
- Simplified end stage renal failure risk prediction model for the low-risk general population with chronic kidney disease Lim CC, Chee ML, Cheng CY, Kwek JL, Foo M, Wong TY, Sabanayagam C. PLoS One, 2019; 14(2): e0212590.
- Deep learning in estimating prevalence and systemic risk factors for diabetic retinopathy: a multi-ethnic study Ting DSW, Cheung CY, Nguyen Q, Sabanayagam C, Lim G, Lim ZW, Tan GSW, Soh YQ, Schmetterer L, Wang YX, Jonas JB, Varma R, Lee ML, Hsu W, Lamoureux E, Cheng CY, Wong TY. NPJ Digit Med, 2019; 2: 24.
- A genome-wide association study identifies genetic loci associated with specific lobar brain volumes van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C. Commun Biol, 2019; 2: 285.
- Prevalence and Risk Factors for Cognitive Impairment and Dementia in Indians: A Multiethnic Perspective from a Singaporean Study Wong MYZ, Tan CS, Venketasubramanian N, Chen C, Ikram MK, Cheng CY, Hilal S. J Alzheimers Dis, 2019a; 71(1): 341-351.
- Genetic variants linked to myopic macular degeneration in persons with high myopia: CREAM Consortium Wong YL, Hysi P, Cheung G, Tedja M, Hoang QV, Tompson SWJ, Whisenhunt KN, Verhoeven V, Zhao W, Hess M, Wong CW, Kifley A, Hosoda Y, Haarman AEG, Hopf S, Laspas P, Sensaki S, Sim X, Miyake M, Tsujikawa A, Lamoureux E, Ohno-Matsui K, Nickels S, Mitchell P, Wong TY, Wang JJ, Hammond CJ, Barathi VA, Cheng CY, Yamashiro K, Young TL, Klaver CCW, Saw SM, Consortium of Refractive Error Myopia. PLoS One, 2019b; 14(8): e0220143.
2018
- Social, health and ocular factors associated with primary open-angle glaucoma amongst Chinese Singaporeans Chiam N, Baskaran M, Li Z, Perera S, Goh D, Husain R, Khor CC, Cheng CY, Aung T, Vithana EN. Clin Exp Ophthalmol. 2018 Jan;46(1):25-34. doi: 10.1111/ceo.13008. Epub 2017 Aug 9
- The Effect of Testing Reliability on Visual Field Sensitivity in Normal Eyes: The Singapore Chinese Eye Study Tan NYQ, Tham YC, Koh V, Nguyen DQ, Cheung CY, Aung T, Wong TY, Cheng CY. Ophthalmology. 2018 Jan;125(1):15-21. doi: 10.1016/j.ophtha.2017.08.002. Epub 2017 Aug 30
- Factors that influence tear meniscus area and conjunctivochalasis: The Singapore Indian eye study Poh S, Lee R, Gao J, Tan C, Gupta P, Sabanayagam C, Cheng CY, Wong TY, Tong L. Ophthalmic Epidemiol. 2018 Feb;25(1):70-78. doi: 10.1080/09286586.2017.1351999. Epub 2017 Sep 14
- Caregiver-Reported Sleep Disturbances Are Associated With Behavioral and Psychological Symptoms in an Asian Elderly Cohort With Cognitive Impairment-No Dementia Xu X, Kan CN, Wong TY, Cheng CY, Ikram MK, Chen CL, Venketasubramanian N. J Geriatr Psychiatry Neurol. 2018 Mar;31(2):70-75. doi: 10.1177/0891988718758203. Epub 2018 Mar 19
- CCDC102B confers risk of low vision and blindness in high myopia Hosoda Y, Yoshikawa M, Miyake M, Tabara Y, Shimada N, Zhao W, Oishi A, Nakanishi H, Hata M, Akagi T, Ooto S, Nagaoka N, Fang Y; Nagahama Study group; Ohno-Matsui K, Cheng CY, Saw SM, Yamada R, Matsuda F, Tsujikawa A, Yamashiro K. Nat Commun. 2018 May 3;9(1):1782. doi: 10.1038/s41467-018-03649-3
- Macular thickness profile and diabetic retinopathy: the Singapore Epidemiology of Eye Diseases Study. Dai W, Tham YC, Cheung N, Yasuda M, Tan NYQ, Cheung CY, Wang JJ, Mitchell P, Sabanayagam C, Wong TY, Cheng CY.Br J Ophthalmol. 2018 Aug;102(8):1072-1076. doi: 10.1136/bjophthalmol-2017-310959. Epub 2017 Nov 24
- Correlation of Color Fundus Photograph Grading with Risks of Early Age-related Macular Degeneration by using Automated OCT-derived Drusen Measurements Cheung CMG, Shi Y, Tham YC, Sabanayagam C, Neelam K, Wang JJ, Mitchell P, Cheng CY, Wong TY, Cheung CYL. Sci Rep. 2018 Aug 28;8(1):12937. doi: 10.1038/s41598-018-31109-x
- Trends of Visual Impairment and Blindness in the Singapore Chinese Population over a Decade Tham YC, Lim SH, Shi Y, Chee ML, Zheng YF, Chua J, Saw SM, Foster P, Aung T, Wong TY, Cheng CY. Sci Rep. 2018 Aug 15;8(1):12224. doi: 10.1038/s41598-018-30004-9
- Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract Tan AG, Kifley A, Holliday EG, Klein BEK, Iyengar SK, Lee KE, Jun GR, Cumming RG, Zhao W, Wong TY, Cheng CY, Mitchell P, Wang JJ. Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4755-4762. doi: 10.1167/iovs.18-24353
- Prevalence, Risk Factors, and Impact of Myopic Macular Degeneration on Visual Impairment and Functioning Among Adults in Singapore Wong YL, Sabanayagam C, Ding Y, Wong CW, Yeo AC, Cheung YB, Cheung G, Chia A, Ohno-Matsui K, Wong TY, Wang JJ, Cheng CY, Hoang QV, Lamoureux E, Saw SM. Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4603-4613. doi: 10.1167/iovs.18-24032
- Risk of Incident Cardiovascular Disease and Cardiovascular Risk Factors in First and Second-Generation Indians: The Singapore Indian Eye Study Gupta P, Gan ATL, Man REK, Fenwick EK, Tham YC, Sabanayagam C, Wong TY, Cheng CY, Lamoureux EL. Sci Rep. 2018 Oct 4;8(1):14805. doi: 10.1038/s41598-018-32833-0
- Haemoglobin, magnetic resonance imaging markers and cognition: a subsample of population-based study Tan B, Venketasubramanian N, Vrooman H, Cheng CY, Wong TY, Chen C, Hilal S. Alzheimers Res Ther. 2018 Nov 6;10(1):114. doi: 10.1186/s13195-018-0440-5
- An Automated Grading System for Detection of Vision-Threatening Referable Diabetic Retinopathy on the Basis of Color Fundus Photographs Li Z, Keel S, Liu C, He Y, Meng W, Scheetz J, Lee PY, Shaw J, Ting D, Wong TY, Taylor H, Chang R, He M. Diabetes Care. 2018 Dec;41(12):2509-2516. doi: 10.2337/dc18-0147. Epub 2018 Oct 1
- Six-Year Incidence of and Risk Factors for Cataract Surgery in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study Tan AG, Kifley A, Tham YC, Shi Y, Chee ML, Sabanayagam C, Tan NYQ, Wong KH, Mitchell P, Cumming RG, Wong TY, Wang JJ, Cheng CY. Ophthalmology. 2018 Dec;125(12):1844-1853. doi: 10.1016/j.ophtha.2018.07.026. Epub 2018 Aug 2
- Human pharyngeal microbiota in age-related macular degeneration Ho EXP, Cheung CMG, Sim S, Chu CW, Wilm A, Lin CB, Mathur R, Wong D, Chan CM, Bhagarva M, Laude A, Lim TH, Wong TY, Cheng CY, Davila S, Hibberd M. PLoS One. 2018 Aug 8;13(8):e0201768. doi: 10.1371/journal.pone.0201768
- Diagnostic accuracy of macular ganglion cell-inner plexiform layer thickness for glaucoma detection in a population-based study: Comparison with optic nerve head imaging parameters Koh V, Tham YC, Cheung CY, Mani B, Wong TY, Aung T, Cheng CY. PLoS One. 2018 Jun 26;13(6):e0199134. doi: 10.1371/journal.pone.0199134
- Homocysteine and Cerebral Atrophy: The Epidemiology of Dementia in Singapore Study Tan B, Venketasubramanian N, Vrooman H, Cheng CY, Wong TY, Ikram MK, Chen C, Hilal S. J Alzheimers Dis. 2018;62(2):877-885. doi: 10.3233/JAD-170796
- Sleep Duration and Diabetic Kidney Disease Tan NYQ, Chan J, Cheng CY, Wong TY, Sabanayagam C. Front Endocrinol (Lausanne). 2019 Jan 14;9:808. doi: 10.3389/fendo.2018.00808
- A genome-wide association study of corneal astigmatism: The CREAM Consortium Shah RL, Li Q, Zhao W, Tedja MS, Tideman JWL, Khawaja AP, Fan Q, Yazar S, Williams KM, Verhoeven VJM, Xie J, Wang YX, Hess M, Nickels S, Lackner KJ, Pärssinen O, Wedenoja J, Biino G, Concas MP, Uitterlinden A, Rivadeneira F, Jaddoe VWV, Hysi PG, Sim X, Tan N, Tham YC, Sensaki S, Hofman A, Vingerling JR, Jonas JB, Mitchell P, Hammond CJ, Höhn R, Baird PN, Wong TY, Cheng CY, Teo YY, Mackey DA, Williams C, Saw SM, Klaver CCW, Guggenheim JA, Bailey-Wilson JE; CREAM Consortium. Mol Vis. 2018 Feb 5;24:127-142
- Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma Shiga Y, Akiyama M, Nishiguchi KM, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, Wakai K, Yoshikawa M, Miyake M, Yamashiro K; Japan Glaucoma Society Omics Group (JGS-OG); Kashiwagi K, Iwata T, Mabuchi F, Takamoto M, Ozaki M, Kawase K, Aihara M, Araie M, Yamamoto T, Kiuchi Y, Nakamura M, Ikeda Y, Sonoda KH, Ishibashi T, Nitta K, Iwase A, Shirato S, Oka Y, Satoh M, Sasaki M, Fuse N, Suzuki Y, Cheng CY, Khor CC, Baskaran M, Perera S, Aung T, Vithana EN, Cooke Bailey JN, Kang JH, Pasquale LR, Haines JL; NEIGHBORHOOD Consortium; Wiggs JL, Burdon KP, Gharahkhani P, Hewitt AW, Mackey DA, MacGregor S, Craig JE, Allingham RR, Hauser M, Ashaye A, Budenz DL, Akafo S, Williams SEI, Kamatani Y, Nakazawa T, Kubo M. Hum Mol Genet. 2018 Apr 15;27(8):1486-1496. doi: 10.1093/hmg/ddy053
- Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases Iglesias AI, Mishra A, Vitart V, Bykhovskaya Y, Höhn R, Springelkamp H, Cuellar-Partida G, Gharahkhani P, Bailey JNC, Willoughby CE, Li X, Yazar S, Nag A, Khawaja AP, Polašek O, Siscovick D, Mitchell P, Tham YC, Haines JL, Kearns LS, Hayward C, Shi Y, van Leeuwen EM, Taylor KD; Blue Mountains Eye Study—GWAS group; Bonnemaijer P, Rotter JI, Martin NG, Zeller T, Mills RA, Souzeau E, Staffieri SE, Jonas JB, Schmidtmann I, Boutin T, Kang JH, Lucas SEM, Wong TY, Beutel ME, Wilson JF; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2); Uitterlinden AG, Vithana EN, Foster PJ, Hysi PG, Hewitt AW, Khor CC, Pasquale LR, Montgomery GW, Klaver CCW, Aung T, Pfeiffer N, Mackey DA, Hammond CJ, Cheng CY, Craig JE, Rabinowitz YS, Wiggs JL, Burdon KP, van Duijn CM, MacGregor S. Nat Commun. 2018 May 14;9(1):1864. doi: 10.1038/s41467-018-03646-6. Erratum in: Nat Commun. 2019 Jan 8;10(1):155
- Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw WY, Tai ES, Sim XL, Huffman JE, Polašek O, Hayward C, Bencic G, Rudan I, Wilson JF; CREAM Consortium; 23andMe Research Team; UK Biobank Eye and Vision Consortium; Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP Jr, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW. Nat Genet. 2018 Jun;50(6):834-848. doi: 10.1038/s41588-018-0127-7. Epub 2018 May 28
- Interethnic analyses of blood pressure loci in populations of East Asian and European descent Takeuchi F, Akiyama M, Matoba N, Katsuya T, Nakatochi M, Tabara Y, Narita A, Saw WY, Moon S, Spracklen CN, Chai JF, Kim YJ, Zhang L, Wang C, Li H, Li H, Wu JY, Dorajoo R, Nierenberg JL, Wang YX, He J, Bennett DA, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Rakugi H, Nakashima E, Isono M, Shirota M, Hozawa A, Ichihara S, Matsubara T, Yamamoto K, Kohara K, Igase M, Han S, Gordon-Larsen P, Huang W, Lee NR, Adair LS, Hwang MY, Lee J, Chee ML, Sabanayagam C, Zhao W, Liu J, Reilly DF, Sun L, Huo S, Edwards TL, Long J, Chang LC, Chen CH, Yuan JM, Koh WP, Friedlander Y, Kelly TN, Bin Wei W, Xu L, Cai H, Xiang YB, Lin K, Clarke R, Walters RG, Millwood IY, Li L, Chambers JC, Kooner JS, Elliott P, van der Harst P; International Genomics of Blood Pressure (iGEN-BP) Consortium; Chen Z, Sasaki M, Shu XO, Jonas JB, He J, Heng CK, Chen YT, Zheng W, Lin X, Teo YY, Tai ES, Cheng CY, Wong TY, Sim X, Mohlke KL, Yamamoto M, Kim BJ, Miki T, Nabika T, Yokota M, Kamatani Y, Kubo M, Kato N. Nat Commun. 2018 Nov 28;9(1):5052. doi: 10.1038/s41467-018-07345-0
- Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Bentley AR, Brown MR, Schwander K, Richard MA, Noordam R, Aschard H, Bartz TM, Bielak LF, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Lohman KK, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Wojczynski MK, Alver M, Boissel M, Cai Q, Campbell A, Chai JF, Chen X, Divers J, Gao C, Goel A, Hagemeijer Y, Harris SE, He M, Hsu FC, Jackson AU, Kähönen M, Kasturiratne A, Komulainen P, Kühnel B, Laguzzi F, Luan J, Matoba N, Nolte IM, Padmanabhan S, Riaz M, Rueedi R, Robino A, Said MA, Scott RA, Sofer T, Stančáková A, Takeuchi F, Tayo BO, van der Most PJ, Varga TV, Vitart V, Wang Y, Ware EB, Warren HR, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Amin N, Amini M, Arking DE, Aung T, Boerwinkle E, Borecki I, Broeckel U, Brown M, Brumat M, Burke GL, Canouil M, Chakravarti A, Charumathi S, Ida Chen YD, Connell JM, Correa A, de Las Fuentes L, de Mutsert R, de Silva HJ, Deng X, Ding J, Duan Q, Eaton CB, Ehret G, Eppinga RN, Evangelou E, Faul JD, Felix SB, Forouhi NG, Forrester T, Franco OH, Friedlander Y, Gandin I, Gao H, Ghanbari M, Gigante B, Gu CC, Gu D, Hagenaars SP, Hallmans G, Harris TB, He J, Heikkinen S, Heng CK, Hirata M, Howard BV, Ikram MA; InterAct Consortium; John U, Katsuya T, Khor CC, Kilpeläinen TO, Koh WP, Krieger JE, Kritchevsky SB, Kubo M, Kuusisto J, Lakka TA, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y, Lin S, Liu J, Liu J, Loh M, Louie T, Mägi R, McKenzie CA, Meitinger T, Metspalu A, Milaneschi Y, Milani L, Mohlke KL, Momozawa Y, Nalls MA, Nelson CP, Sotoodehnia N, Norris JM, O’Connell JR, Palmer ND, Perls T, Pedersen NL, Peters A, Peyser PA, Poulter N, Raffel LJ, Raitakari OT, Roll K, Rose LM, Rosendaal FR, Rotter JI, Schmidt CO, Schreiner PJ, Schupf N, Scott WR, Sever PS, Shi Y, Sidney S, Sims M, Sitlani CM, Smith JA, Snieder H, Starr JM, Strauch K, Stringham HM, Tan NYQ, Tang H, Taylor KD, Teo YY, Tham YC, Turner ST, Uitterlinden AG, Vollenweider P, Waldenberger M, Wang L, Wang YX, Wei WB, Williams C, Yao J, Yu C, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Deary IJ, Esko T, Farrall M, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Jonas JB, Kamatani Y, Kato N, Kooner JS, Kutalik Z, Laakso M, Laurie CC, Leander K, Lehtimäki T, Study LC, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Polasek O, Porteous DJ, Rauramaa R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zheng W, Bouchard C, Christensen K, Evans MK, Gudnason V, Horta BL, Kardia SLR, Liu Y, Pereira AC, Psaty BM, Ridker PM, van Dam RM, Gauderman WJ, Zhu X, Mook-Kanamori DO, Fornage M, Rotimi CN, Cupples LA, Kelly TN, Fox ER, Hayward C, van Duijn CM, Tai ES, Wong TY, Kooperberg C, Palmas W, Rice K, Morrison AC, Elliott P, Caulfield MJ, Munroe PB, Rao DC, Province MA, Levy D. PLoS One. 2018 Jun 18;13(6):e0198166. doi: 10.1371/journal.pone.0198166
- A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure Sung YJ, Winkler TW, de Las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I, Guo X, Franceschini N, Lu Y, Cheng CY, Sim X, Vojinovic D, Marten J, Musani SK, Li C, Feitosa MF, Kilpeläinen TO, Richard MA, Noordam R, Aslibekyan S, Aschard H, Bartz TM, Dorajoo R, Liu Y, Manning AK, Rankinen T, Smith AV, Tajuddin SM, Tayo BO, Warren HR, Zhao W, Zhou Y, Matoba N, Sofer T, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Gandin I, Gao C, Giulianini F, Goel A, Harris SE, Hartwig FP, Horimoto ARVR, Hsu FC, Jackson AU, Kähönen M, Kasturiratne A, Kühnel B, Leander K, Lee WJ, Lin KH, ‘an Luan J, McKenzie CA, Meian H, Nelson CP, Rauramaa R, Schupf N, Scott RA, Sheu WHH, Stančáková A, Takeuchi F, van der Most PJ, Varga TV, Wang H, Wang Y, Ware EB, Weiss S, Wen W, Yanek LR, Zhang W, Zhao JH, Afaq S, Alfred T, Amin N, Arking D, Aung T, Barr RG, Bielak LF, Boerwinkle E, Bottinger EP, Braund PS, Brody JA, Broeckel U, Cabrera CP, Cade B, Caizheng Y, Campbell A, Canouil M, Chakravarti A; CHARGE Neurology Working Group; Chauhan G, Christensen K, Cocca M; COGENT-Kidney Consortium; Collins FS, Connell JM, de Mutsert R, de Silva HJ, Debette S, Dörr M, Duan Q, Eaton CB, Ehret G, Evangelou E, Faul JD, Fisher VA, Forouhi NG, Franco OH, Friedlander Y, Gao H; GIANT Consortium; Gigante B, Graff M, Gu CC, Gu D, Gupta P, Hagenaars SP, Harris TB, He J, Heikkinen S, Heng CK, Hirata M, Hofman A, Howard BV, Hunt S, Irvin MR, Jia Y, Joehanes R, Justice AE, Katsuya T, Kaufman J, Kerrison ND, Khor CC, Koh WP, Koistinen HA, Komulainen P, Kooperberg C, Krieger JE, Kubo M, Kuusisto J, Langefeld CD, Langenberg C, Launer LJ, Lehne B, Lewis CE, Li Y; Lifelines Cohort Study; Lim SH, Lin S, Liu CT, Liu J, Liu J, Liu K, Liu Y, Loh M, Lohman KK, Long J, Louie T, Mägi R, Mahajan A, Meitinger T, Metspalu A, Milani L, Momozawa Y, Morris AP, Mosley TH Jr, Munson P, Murray AD, Nalls MA, Nasri U, Norris JM, North K, Ogunniyi A, Padmanabhan S, Palmas WR, Palmer ND, Pankow JS, Pedersen NL, Peters A, Peyser PA, Polasek O, Raitakari OT, Renström F, Rice TK, Ridker PM, Robino A, Robinson JG, Rose LM, Rudan I, Sabanayagam C, Salako BL, Sandow K, Schmidt CO, Schreiner PJ, Scott WR, Seshadri S, Sever P, Sitlani CM, Smith JA, Snieder H, Starr JM, Strauch K, Tang H, Taylor KD, Teo YY, Tham YC, Uitterlinden AG, Waldenberger M, Wang L, Wang YX, Wei WB, Williams C, Wilson G, Wojczynski MK, Yao J, Yuan JM, Zonderman AB, Becker DM, Boehnke M, Bowden DW, Chambers JC, Chen YI, de Faire U, Deary IJ, Esko T, Farrall M, Forrester T, Franks PW, Freedman BI, Froguel P, Gasparini P, Gieger C, Horta BL, Hung YJ, Jonas JB, Kato N, Kooner JS, Laakso M, Lehtimäki T, Liang KW, Magnusson PKE, Newman AB, Oldehinkel AJ, Pereira AC, Redline S, Rettig R, Samani NJ, Scott J, Shu XO, van der Harst P, Wagenknecht LE, Wareham NJ, Watkins H, Weir DR, Wickremasinghe AR, Wu T, Zheng W, Kamatani Y, Laurie CC, Bouchard C, Cooper RS, Evans MK, Gudnason V, Kardia SLR, Kritchevsky SB, Levy D, O’Connell JR, Psaty BM, van Dam RM, Sims M, Arnett DK, Mook-Kanamori DO, Kelly TN, Fox ER, Hayward C, Fornage M, Rotimi CN, Province MA, van Duijn CM, Tai ES, Wong TY, Loos RJF, Reiner AP, Rotter JI, Zhu X, Bierut LJ, Gauderman WJ, Caulfield MJ, Elliott P, Rice K, Munroe PB, Morrison AC, Cupples LA, Rao DC, Chasman DI. Am J Hum Genet. 2018 Mar 1;102(3):375-400. doi: 10.1016/j.ajhg.2018.01.015. Epub 2018 Feb 15
- Evaluation of Primary Angle-Closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-Closure Disease Nongpiur ME, Cheng CY, Duvesh R, Vijayan S, Baskaran M, Khor CC, Allen J, Kavitha S, Venkatesh R, Goh D, Husain R, Boey PY, Quek D, Ho CL, Wong TT, Perera S, Wong TY, Krishnadas SR, Sundaresan P, Aung T, Vithana EN.Ophthalmology. 2018 May;125(5):664-670. doi: 10.1016/j.ophtha.2017.11.016. Epub 2018 Jan 6
- Inter-relationship between ocular perfusion pressure, blood pressure, intraocular pressure profiles and primary open-angle glaucoma: the Singapore Epidemiology of Eye Diseases study Tham YC, Lim SH, Gupta P, Aung T, Wong TY, Cheng CYBr J Ophthalmol. 2018 Oct;102(10):1402-1406. doi: 10.1136/bjophthalmol-2017-311359. Epub 2018 Jan 13
- Diabetic Retinopathy in the Asia-Pacific Chua J, Lim CXY, Wong TY, Sabanayagam CAsia Pac J Ophthalmol (Phila). 2018 Jan-Feb;7(1):3-16. doi: 10.22608/APO.2017511. Epub 2017
- Prevalence, subtypes, severity and determinants of ocular trauma: The Singapore Chinese Eye Study Wong MY, Man RE, Gupta P, Sabanayagam C, Wong TY, Cheng CY, Lamoureux EL.Br J Ophthalmol. 2018 Feb;102(2):204-209. doi: 10.1136/bjophthalmol-2017-310564. Epub 2017 Jun 16
- Factors affecting signal strength in spectral-domain optical coherence tomography Lee R, Tham YC, Cheung CY, Sidhartha E, Siantar RG, Lim SH, Wong TY, Cheng CY.Acta Ophthalmol. 2018 Feb;96(1):e54-e58. doi: 10.1111/aos.13443. Epub 2017 Apr 9.
- Differential effect of body mass index on the incidence of diabetes and diabetic retinopathy in two Asian populations Chan JCY, Chee ML, Tan NYQ, Cheng CY, Wong TY, Sabanayagam CNutr Diabetes. 2018 Mar 7;8(1):16. doi: 10.1038/s41387-018-0018-0.
- Impact of Incidence and Progression of Diabetic Retinopathy on Vision-Specific Functioning Gupta P, Liang Gan AT, Kidd Man RE, Fenwick EK, Kumari N, Tan G, Mitchell P, Sabanayagam C, Wong TY, Cheng CY, Lamoureux ELSend toOphthalmology. 2018 Sep;125(9):1401-1409. doi: 10.1016/j.ophtha.2018.02.011. Epub 2018 Mar 20
- Direct and Indirect Associations Between Diabetes and Intraocular Pressure: The Singapore Epidemiology of Eye Diseases Study. Luo XY, Tan NYQ, Chee ML, Shi Y, Tham YC, Wong TY, Wang JJ, Cheng CYInvest Ophthalmol Vis Sci. 2018 Apr 1;59(5):2205-2211. doi: 10.1167/iovs.17-23013.
- Ethnic Differences in the Prevalence and Risk Factors of Diabetic Retinopathy: The Singapore Epidemiology of Eye Diseases Study Tan GS, Gan A, Sabanayagam C, Tham YC, Neelam K, Mitchell P, Wang JJ, Lamoureux EL, Cheng CY, Wong TY.Ophthalmology. 2018 Apr;125(4):529-536. doi: 10.1016/j.ophtha.2017.10.026. Epub 2017 Dec 6.
- Falls and Recurrent Falls among Adults in A Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study Dai W, Tham YC, Chee ML, Tan NYQ, Wong KH, Majithia S, Sabanayagam C, Lamoureux E, Wong TY, Cheng CYSci Rep. 2018 May 15;8(1):7575. doi: 10.1038/s41598-018-25894-8.
- Choroidal Nevi in the Singapore Epidemiology of Eye Disease Study. Ng SR, Zhao W, Mitchell P, Wang JJ, Foo HXV, Neelam K, Cheng CY, Wong TY, Cheung NOphthalmology. 2018 May;125(5):784-786. doi: 10.1016/j.ophtha.2017.12.019. Epub 2018 Feb 1.
- Associations between sleep duration, sleep quality and diabetic retinopathy. Tan NYQ, Chew M, Tham YC, Nguyen QD, Yasuda M, Cheng CY, Wong TY, Sabanayagam CPLoS One. 2018 May 24;13(5):e0196399. doi: 10.1371/journal.pone.0196399. eCollection 2018.
- Associations of Peripapillary Atrophy and Fundus Tessellation with Diabetic Retinopathy. Nicholas Y.Q. Tan, Yih-Chung Tham,, Yang Ding, Masayuki Yasuda, Charumathi Sabanayagam, Seang-Mei Saw, Jie Jin Wang, Paul Mitchell, Tien Yin Wong, Ching-Yu ChengOphthalmology Retina, Volume 2 , Issue 6 , 574 – 581
- Six-Year Incidence and Risk Factors of Age-Related Macular Degeneration in Singaporean Indians: The Singapore Indian Eye Study.Foo VHX, Yanagi Y, Nguyen QD, Sabanayagam C, Lim SH, Neelam K, Wang JJ, Mitchell P, Cheng CY, Wong TY, Cheung CMGSci Rep. 2018 Jun 11;8(1):8869
2017
- Cumulative incidence and risk factors of prediabetes and type 2 diabetes in a Singaporean Malay cohort Man RE, Charumathi S, Gan AT, Fenwick EK, Tey CS, Chua J, Wong TY, Cheng CY, Lamoureux EL.Diabetes Res Clin Pract. 2017 May;127:163-171
- Singapore Indian Eye Study 2: methodology and impact of migration on systemic and eye outcomes Sabanayagam C, Yip W, Gupta P, Mohd Abdul RB, Lamoureux E, Kumari N, Cheung GC, Cheung CY, Wang JJ, Cheng CY, Wong TYClin Exp Ophthalmol. 2017 May 4. doi: 10.1111/ceo.12974
- Urinary Isoprostane Levels and Age-Related Macular Degeneration Sabanayagam C, Lye WK, Januszewski A, Banu Binte Mohammed Abdul R, Cheung GCM, Kumari N, Wong TY, Cheng CY, Lamoureux E.Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2538-2543
- Retinal vascular geometry and 6 year incidence and progression of diabetic retinopathy Cheung CY, Sabanayagam C, Law AK, Kumari N, Ting DS, Tan G, Mitchell P, Cheng CY, Wong TY.Diabetologia. 2017 Jun 16. doi: 10.1007/s00125-017-4333-0. [Epub ahead of print]
- Characterisation of choroidal morphological and vascular features in diabetes and diabetic retinopathy Gupta P, Thakku SG, Sabanayagam C, Tan G, Cheung CM, Lamoureux EL, Wong TY, Cheng CYBr J Ophthalmol. 2017 Aug;101(8):1038-1044
- Retinal Vascular Imaging Markers and Incident Chronic Kidney Disease: A Prospective Cohort Study Yip W, Ong PG, Teo BW, Cheung CY, Tai ES, Cheng CY, Lamoureux E, Wong TY, Sabanayagam C.Sci Rep. 2017 Aug 24;7(1):9374.
- Is Corneal Arcus Independently Associated with Incident Cardiovascular Disease in Asians? Zheng Wong MY, Kidd Man RE, Gupta P, Lim SH, Lim B, Tham YC, Sabanayagam C, Wong TY, Cheng CY, Lamoureux EL.Am J Ophthalmol. 2017 Sep 11. pii: S0002-9394(17)30379-3.
- Factors that influence tear meniscus area and conjunctivochalasis: The Singapore Indian eye study Poh S, Lee R, Gao J, Tan C, Gupta P, Sabanayagam C, Cheng CY, Wong TY, Tong L.Ophthalmic Epidemiol. 2018 Feb;25(1):70-78. doi: 10.1080/09286586.2017.1351999. Epub 2017 Sep 14
- Comparison of Corneal Biomechanical Properties between Indian and Chinese Adults Chua J, Nongpiur ME, Zhao W, Tham YC, Gupta P, Sabanayagam C, Aung T, Wong TY, Cheng CY.Ophthalmology. 2017 Sep;124(9):1271-1279.
- Six-Year Incidence of Age-Related Macular Degeneration in Asian Malays: The Singapore Malay Eye Study Cheung CMG, Ong PG, Neelam K, Tan PC, Shi Y, Mitchell P, Wang JJ, Sabanayagam C, Cheng CY, Wong TY.Ophthalmology. 2017 Sep;124(9):1305-1313.
- Incidence and risk factors of symptomatic dry eye disease in Asian Malays from the Singapore Malay Eye Study Man REK, Veerappan AR, Tan SP, Fenwick EK, Sabanayagam C, Chua J, Leong YY, Wong TY, Lamoureux EL, Cheng CY, Tong L.Ocul Surf. 2017 Oct;15(4):742-748. doi: 10.1016/j.jtos.2017.04.004. Epub 2017 Apr 23.
- Prevalence and Associations of Retinal Emboli With Ethnicity, Stroke, and Renal Disease in a Multiethnic Asian Population: The Singapore Epidemiology of Eye Disease Study Cheung N, Teo K, Zhao W, Wang JJ, Neelam K, Tan NYQ, Mitchell P, Cheng CY, Wong TY.JAMA Ophthalmol. 2017 Oct 1;135(10):1023-1028. doi: 10.1001/jamaophthalmol.2017.2972.
- Association Between the Severity of Diabetic Retinopathy and Falls in an Asian Population With Diabetes: The Singapore Epidemiology of Eye Diseases Study Gupta P, Aravindhan A, Gan ATL, Man REK, Fenwick EK, Mitchell P, Tan N, Sabanayagam C, Wong TY, Cheng CY, Lamoureux ELJAMA Ophthalmol. 2017 Dec 1;135(12):1410-1416. doi: 10.1001/jamaophthalmol.2017.4983.
- Genome-wide association study identifies a missense variant at APOA5 for coronary artery disease in Multi-Ethnic Cohorts from Southeast Asia Han Y, Dorajoo R, Chang X, Wang L, Khor CC, Sim X, Cheng CY, Shi Y, Tham YC, Zhao W, Chee ML, Sabanayagam C, Chee ML, Tan N, Wong TY, Tai ES, Liu J, Goh DYT, Yuan JM, Koh WP, van Dam RM, Low AF, Chan MY, Friedlander Y, Heng CK.Sci Rep. 2017 Dec 20;7(1):17921. doi: 10.1038/s41598-017-18214-z.
- Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study Sobrin L, Chong YH, Fan Q, Gan A, Stanwyck LK, Kaidonis G, Craig JE, Kim J, Liao WL, Huang YC, Lee WJ, Hung YJ, Guo X, Hai Y, Ipp E, Pollack S, Hancock H, Price A, Penman A, Mitchell P, Liew G, Smith AV, Gudnason V, Tan G, Klein BEK, Kuo J, Li X, Christiansen MW, Psaty BM, Sandow K; Asian Genetic Epidemiology Network Consortium, Jensen RA, Klein R, Cotch MF, Wang JJ, Jia Y, Chen CJ15, Chen YI12, Rotter JI12, Tsai FJ, Hanis CL, Burdon KP, Wong TY, Cheng CY.Diabetes. 2017 Dec;66(12):3130-3141. doi: 10.2337/db17-0398. Epub 2017 Sep 26.
2016
- Relationship between peripapillary choroid and retinal nerve fiber layer thickness in a population-based sample of non-glaucomatous eyes Gupta P, Cheung CY, Baskaran M, Tian J, Marziliano P, Lamoureux EL, Cheung CG, Aung T, Wong TY, Cheng CY Am J Ophthalmol. 2016 Jan; 161:4-11.e1-2
- Increased burden of vision impairment and eye diseases in persons with chronic kidney disease – A Population-Based Study Wong CW, Lamoureux E, Cheng CY, Cheung GC, Tai ES, Wong TY, Charumathi S EBioMedicine. 2016 Jan; 5:193-197
- Joint effects of intraocular pressure and myopia on risk of primary open angle glaucoma: the Singapore Epidemiology of Eye Diseases Study Tham YC, Aung T, Fan Q, Saw SM, Siantar RG, Wong TY, Cheng CY Sci Rep. 2016 Jan 13; 6:19320
- Choroidal vascularity index as a measure of the vascular status of the choroid: Measurements in healthy eyes from a population-based study Agrawal R, Gupta P, Tan KA, Cheung G, Wong TY, Cheng CY Sci Rep. 2016 Feb 12; 6: 21090
- Assessing the Causality between Blood Pressure and Retinal Vascular Caliber through Mendelian Randomisation Li LJ, Liao J, Cheung CY, Ikram MK, Shyong TE, Wong TY, Cheng CY Sci Rep. 2016 Feb 25; 6:22031
- Novel genetic loci associated with retinal microvascular diameter Jensen RA, Sim X, Smith AV, Li X, Jakobsdóttir J, Cheng CY, Brody JA, Cotch MF, McKnight B, Klein R, Wang JJ, Kifley A, Harris TB, Launer LJ, Taylor KD, Klein BE, Raffel LJ, Li X, Ikram MA, Klaver CC, van der Lee SJ, Mutlu U, Hofman A, Uitterlinden AG, Liu C, Kraja AT; CHARGE Exome Chip Blood Pressure Consortium, Mitchell P, Gudnason V, Rotter JI, Boerwinkle E, van Duijn CM, Psaty BM, Wong TY Circ Cardiovasc Genet. 2016 Feb; 9(1):45-54
- Assessing the causality between blood pressure and retinal vascular caliber through Mendelian randomization Li LJ, Liao J, Cheung CY, Ikram MK, Tai ES, Wong TY, Cheng CY Sci Rep. 2016 Feb; 6:22031
- Retinal vein occlusion in a multi-ethnic Asian population: the Singapore Epidemiology of Eye Disease Study Koh V, Cheung CY, Li X, Tian D, Wang JJ, Mitchell P, Cheng CY, Wong TY Ophthalmic Epidemiol. 2016 Feb;23(1):6-13
- Cystatin C, Chronic Kidney Disease and Retinopathy in Adults without Diabetes Ng WY, Teo BW, E Tai ES, Sethi S, Lamoureux EL, Wong TY, Sabanayagam C Eur J Prev Cardiol. 2016 Feb 29. pii: 2047487316637182 . [Epub ahead of print]
- Relationship of ocular and systemic factors to the visibility of choroid-scleral interface using spectral domain optical coherence tomography Gupta P, Cheng CY, Cheung GC, Htoon HM, Zheng YF, Lamoureux EL, Tin A, Wong TY, Cheung CY Acta Ophthalmologica. 2016 Mar; 94(2):e142-9
- Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J, Gharahkhani P, Venturini C, Miyake M, Hewitt AW, Guo X, Mazur J, Huffman JE, Williams KM, Polasek O, Campbell H, Rudan I, Vatavuk Z, Wilson JF, Joshi PK, McMahon G, St Pourcain B, Evans DM, Simpson CL, Schwantes-An TH, Igo RP, Mirshahi A, Cougnard-Gregoire A, Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppala I, Zeller T, Meitinger T; Consortium for Refractive Error and Myopia (CREAM), Ried JS, Gieger C, Portas L, van Leeuwen EM, Amin N, Uitterlinden AG, Rivadeneira F, Hofman A, Vingerling JR, Wang YX, Wang X, Tai-Hui Boh E, Ikram MK, Sabanayagam C, Gupta P, Tan V, Zhou L, Ho CE, Lim W, Beuerman RW, Siantar R, Tai ES, Vithana E, Mihailov E, Khor CC, Hayward C, Luben RN, Foster PJ, Klein BE, Klein R, Wong HS, Mitchell P, Metspalu A, Aung T, Young TL, He M, Pärssinen O, van Duijn CM, Jin Wang J, Williams C, Jonas JB, Teo YY, Mackey DA, Oexle K, Yoshimura N, Paterson AD, Pfeiffer N, Wong TY, Baird PN, Stambolian D, Wilson JE, Cheng CY,‡ Hammond CJ,‡ Klaver CC,‡ Saw SM Nat Commun. 2016 Mar; 7:11008. doi: 10.1038/ncomms11008
- Visually significant cataract: a global challenge Chua J, Cheng CY Experiment Ophthalmol. 2016 Mar; 44(2):85-6
- Elevated serum leptin, adiponectin and leptin to adiponectin ratio is associated with chronic kidney disease in Asian adults Lim CC, Teo BW, Tai ES, Lim SC, Chan CM, Sethi S, Wong TY, Sabanayagam C PLoS One. 2015 Mar 20; 10(3):e0122009
- Assessment of the psychometric properties of the Chinese impact of vision impairment questionnaire in a population-based study: findings from the Singapore Chinese Eye Study Fenwick EK, Ong PG, Sabanayagam C, Rees G, Xie J, Holloway E, Cheng CY, Wong TY, Lim B, Tan PC, Lamoureux EL Qual Life Res. 2016 Apr; 25(4):871-80
- Evaluation of trans-ethnic fine-mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations Wang X, Cheng CY, Liao J, Sim X, Liu J, Chia KS, Tai ES, Little P, Khor CC, Aung T, Wong TY, Teo YY Eu J Hum Genet. 2016 Apr; 24(4):592-9
- Retinal Ganglion Cell Neuronal Damage in Diabetes and Diabetic Retinopathy Ng DS, Chiang PP, Tan G, Cheung CM, Cheng CY, Cheung CY, Wong TY, Lamoureux EL, Ikram MK Clin Experiment Ophthalmol. 2016 May;44(4):243-50
- Determinants of pupil diameters and pupil dynamics in an adult Chinese population Zheng C, de Leon JM, Cheung CY, Narayanaswamy AK, Ong SH, Tan CW, Chew PT, Perera SA, Wong TY, Aung T Graefes Arch Clin Exp Ophthalmol. 2016 May; 254(5):929-36
- Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma Khor CC, Do T, Jia H, Nakano M, George R, Abu-Amero K, Duvesh R, Chen LJ, Li Z, Nongpiur ME, Perera SA, Qiao C, Wong HT, Sakai H, Barbosa de Melo M, Lee MC, Chan AS, Azhany Y, Dao TL, Ikeda Y, Perez-Grossmann RA, Zarnowski T, Day AC, Jonas JB, Tam PO, Tran TA, Ayub H, Akhtar F, Micheal S, Chew PT, Aljasim LA, Dada T, Luu TT, Awadalla MS, Kitnarong N, Wanichwecharungruang B, Aung YY, Mohamed-Noor J, Vijayan S, Sarangapani S, Husain R, Jap A, Baskaran M, Goh D, Su DH, Wang H, Yong VK, Yip LW, Trinh TB, Makornwattana M, Nguyen TT, Leuenberger EU, Park KH, Wiyogo WA, Kumar RS, Tello C, Kurimoto Y, Thapa SS, Pathanapitoon K, Salmon JF, Sohn YH, Fea A, Ozaki M, Lai JS, Tantisevi V, Khaing CC, Mizoguchi T, Nakano S, Kim CY, Tang G, Fan S, Wu R, Meng H, Nguyen TT, Tran TD, Ueno M, Martinez JM, Ramli N, Aung YM, Reyes RD, Vernon SA, Fang SK, Xie Z, Chen XY, Foo JN, Sim KS, Wong TT, Quek DT, Venkatesh R, Kavitha S, Krishnadas SR, Soumittra N, Shantha B, Lim BA, Ogle J, de Vasconcellos JP, Costa VP, Abe RY, de Souza BB, Sng CC, Aquino MC, Kosior-Jarecka E, Fong GB, Tamanaja VC, Fujita R, Jiang Y, Waseem N, Low S, Pham HN, Al-Shahwan S, Craven ER, Khan MI, Dada R, Mohanty K, Faiq MA, Hewitt AW, Burdon KP, Gan EH, Prutthipongsit A, Patthanathamrongkasem T, Catacutan MA, Felarca IR, Liao CS, Rusmayani E, Istiantoro VW, Consolandi G, Pignata G, Lavia C, Rojanapongpun P, Mangkornkanokpong L, Chansangpetch S, Chan JC, Choy BN, Shum JW, Than HM, Oo KT, Han AT, Yong VH, Ng XY, Goh SR, Chong YF, Hibberd ML, Seielstad M, Png E, Dunstan SJ, Chau NV, Bei J, Zeng YX, Karkey A, Basnyat B, Pasutto F, Paoli D, Frezzotti P, Wang JJ, Mitchell P, Fingert JH, Allingham RR, Hauser MA, Lim ST, Chew SH, Ebstein RP, Sakuntabhai A, Park KH, Ahn J, Boland G, Snippe H, Stead R, Quino R, Zaw SN, Lukasik U, Shetty R, Zahari M, Bae HW, Oo NL, Kubota T, Manassakorn A, Ho WL, Dallorto L, Hwang YH, Kiire CA, Kuroda M, Djamal ZE, Peregrino JI, Ghosh A, Jeoung JW, Hoan TS, Srisamran N, Sandragasu T, Set SH, Doan VH, Bhattacharya SS, Ho CL, Tan DT, Sihota R, Loon SC, Mori K, Kinoshita S, Hollander AI, Qamar R, Wang YX, Teo YY, Tai ES, Hartleben-Matkin C, Lozano-Giral D, Saw SM, Cheng CY, Zenteno JC, Pang CP, Bui HT, Hee O, Craig JE, Edward DP, Yonahara M, Neto JM, Guevara-Fujita ML, Xu L, Ritch R, Liza-Sharmini AT, Wong TY, Al-Obeidan S, Do NH, Sundaresan P, Tham CC, Foster PJ, Vijaya L, Tashiro K, Vithana EN, Wang N, Aung T Nat Genet. 2016 May; 48(5):556-62
- Cerebral microbleeds and neuropsychiatric symptoms in an elderly Asian cohort Xu X, Chan QL, Hilal S, Goh WK, Ikram MK, Wong TY, Cheng CY, Chen CL, Venketasubramanian N J Neurol Neurosurg Psychiatry. 2016 Jun 3. pii: jnnp-2016-313271. doi: 10.1136/jnnp-2016-313271. [Epub ahead of print]
- Prevalence and risk factors for epiretinal membrane: the Singapore Epidemiology of Eye Disease study Cheung N, Tan SP, Lee SY, Cheung GC, Tan G, Kumar N, Cheng CY, Wong TY Br J Ophthalmol. 2016 Jun 24. pii: bjophthalmol-2016-308563. doi: 10.1136/bjophthalmol-2016-308563. [Epub ahead of print]
- Joint Effect of Early Microvascular Damage in the Eye & Kidney on Risk of Cardiovascular Events Yip W, Sabanayagam C, Ong PG, Patel UD, Chow KY, Tai ES, Ling LH, Wong TY, Cheung CY Sci Rep. 2016 Jun 8; 6:27442
- Inter-Relationships Between Retinal Vascular Caliber, Retinal Nerve Fiber Layer Thickness, and Glaucoma: A Mediation Analysis Approach Tham YC, Siantar RG, Cheung CY, Tan SP, Koh VT, Aung T, Wong TY, Cheng CY Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3803-9. doi: 10.1167/iovs.15-18683
- Age-related macular degeneration and polypoidal choroidal vasculopathy in Asians Wong CW, Yanagi Y, Lee WK, Ogura Y, Yeo I, Wong TY, Cheung CM Prog Retin Eye Res. 2016 Jul;53:107-39
- Bayesian reclassification statistics for assessing improvements in diagnostic accuracy Huang Z, Li J, Cheng CY, Cheung C, Wong TY Stat Med. 2016 Jul 10; 35(15):2574-92
- Posterior Eye Shape Measurement With Retinal OCT Compared to MRI Kuo AN, Verkicharla PK, McNabb RP, Cheung CY, Hilal S, Farsiu S, Chen C, Wong TY, Ikram MK, Cheng CY, Young TL, Saw SM, Izatt JA Invest Ophthalmol Vis Sci. 2016 Jul 1;57(9):OCT196-203
- Association of Vision Impairment and Major Eye Diseases With Mobility and Independence in a Chinese Population Fenwick EK, Ong PG, Man RE, Cheng CY, Sabanayagam C, Wong TY, Lamoureux EL JAMA Ophthalmol. 2016 Oct 1;134(10):1087-1093
- Ten Emerging Trends in the Epidemiology of Diabetic Retinopathy Sabanayagam C, Yip W, Ting DS, Tan G, Wong TY Ophthalmic Epidemiol. 2016 Aug;23(4):209-22
- The genetic architecture of type 2 diabetes Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ, Rivas MA, Perry JR, Sim X, Blackwell TW, Robertson NR, Rayner NW, Cingolani P, Locke AE, Fernandez Tajes J, Highland HM, Dupuis J, Chines PS, Lindgren CM, Hartl C, Jackson AU, Chen H, Huyghe JR, van de Bunt M, Pearson RD, Kumar A, Müller-Nurasyid M, Grarup N, Stringham HM, Gamazon ER, Lee J, Chen Y, Scott RA, Below JE, Chen P, Huang J, Go MJ, Stitzel ML, Pasko D, Parker SC, Varga TV, Green T, Beer NL, Day-Williams AG, Ferreira T, Fingerlin T, Horikoshi M, Hu C, Huh I, Ikram MK, Kim BJ, Kim Y, Kim YJ, Kwon MS, Lee J, Lee S, Lin KH, Maxwell TJ, Nagai Y, Wang X, Welch RP, Yoon J, Zhang W, Barzilai N, Voight BF, Han BG, Jenkinson CP, Kuulasmaa T, Kuusisto J, Manning A, Ng MC, Palmer ND, Balkau B, Stancáková A, Abboud HE, Boeing H, Giedraitis V, Prabhakaran D, Gottesman O, Scott J, Carey J, Kwan P, Grant G, Smith JD, Neale BM, Purcell S, Butterworth AS, Howson JM, Lee HM, Lu Y, Kwak SH, Zhao W, Danesh J, Lam VK, Park KS, Saleheen D, So WY, Tam CH, Afzal U, Aguilar D, Arya R, Aung T, Chan E, Navarro C, Cheng CY, Palli D, Correa A, Curran JE, Rybin D, Farook VS, Fowler SP, Freedman BI, Griswold M, Hale DE, Hicks PJ, Khor CC, Kumar S, Lehne B, Thuillier D, Lim WY, Liu J, van der Schouw YT, Loh M, Musani SK, Puppala S, Scott WR, Yengo L, Tan ST, Taylor HA Jr, Thameem F, Wilson G Sr, Wong TY, Njølstad PR, Levy JC, Mangino M, Bonnycastle LL, Schwarzmayr T, Fadista J, Surdulescu GL, Herder C, Groves CJ, Wieland T, Bork-Jensen J, Brandslund I, Christensen C, Koistinen HA, Doney AS, Kinnunen L, Esko T, Farmer AJ, Hakaste L, Hodgkiss D, Kravic J, Lyssenko V, Hollensted M, Jørgensen ME, Jørgensen T, Ladenvall C, Justesen JM, Käräjämäki A, Kriebel J, Rathmann W, Lannfelt L, Lauritzen T, Narisu N, Linneberg A, Melander O, Milani L, Neville M, Orho-Melander M, Qi L, Qi Q, Roden M, Rolandsson O, Swift A, Rosengren AH, Stirrups K, Wood AR, Mihailov E, Blancher C, Carneiro MO, Maguire J, Poplin R, Shakir K, Fennell T, DePristo M, Hrabé de Angelis M, Deloukas P, Gjesing AP, Jun G, Nilsson P, Murphy J, Onofrio R, Thorand B, Hansen T, Meisinger C, Hu FB, Isomaa B, Karpe F, Liang L, Peters A, Huth C, O’Rahilly SP, Palmer CN, Pedersen O, Rauramaa R, Tuomilehto J, Salomaa V, Watanabe RM, Syvänen AC, Bergman RN, Bharadwaj D, Bottinger EP, Cho YS, Chandak GR, Chan JC, Chia KS, Daly MJ, Ebrahim SB, Langenberg C, Elliott P, Jablonski KA, Lehman DM, Jia W, Ma RC, Pollin TI, Sandhu M, Tandon N, Froguel P, Barroso I, Teo YY, Zeggini E, Loos RJ, Small KS, Ried JS, DeFronzo RA, Grallert H, Glaser B, Metspalu A, Wareham NJ, Walker M, Banks E, Gieger C, Ingelsson E, Im HK, Illig T, Franks PW, Buck G, Trakalo J, Buck D, Prokopenko I, Mägi R, Lind L, Farjoun Y, Owen KR, Gloyn AL, Strauch K, Tuomi T, Kooner JS, Lee JY, Park T, Donnelly P, Morris AD, Hattersley AT, Bowden DW, Collins FS, Atzmon G, Chambers JC, Spector TD, Laakso M, Strom TM, Bell GI, Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Burtt NP, Mohlke KL, Meitinger T, Groop L, Abecasis G, Florez JC, Scott LJ, Morris AP, Kang HM, Boehnke M, Altshuler D, McCarthy MI Nature. 2016 Aug 4;536(7614):41-7
- Prevalence, Correlates, and Impact of Uncorrected Presbyopia in a Multi-Ethnic Asian Population Man RE, Fenwick EK, Sabanayagam C, Li LJ, Gupta P, Tham YC, Wong TY, Cheng CY, Lamoureux EL Am J Ophthalmol. 2016 Aug;168:191-200
- Visual Impairment in Old and Very Old Community-dwelling Asian Adults Sabanayagam C, Fenwick E, Ong PG, Tey ML, Tapp R, Cheng CY, Cheung GC, Aung T, Wong TY, Lamoureux E Ophthalmology. 2016 Nov;123(11):2436-2438
- The impact of typical neovascular age-related macular degeneration and polypoidal choroidal vasculopathy on vision-related quality of life in Asian patients Fenwick EK, Cheung CM, Ong PG, Tan G, Lee SY, Yeo I, Cheng CY, Wong TY, Lamoureux EL Br J Ophthalmol. 2016 Aug 2. pii: bjophthalmol-2016-308541. doi: 10.1136/bjophthalmol-2016-308541. [Epub ahead of print]
- Vision impairment and major eye diseases reduce vision-specific emotional well-being in a Chinese population Fenwick EK, Ong PG, Man RE, Sabanayagam C, Cheng CY, Wong TY, Lamoureux EL Br J Ophthalmol. 2016 Aug 26. pii: bjophthalmol-2016-308701. doi: 10.1136/bjophthalmol-2016-308701. [Epub ahead of print]
- Interaction Between Peroxisome Proliferator Activated Receptor ? and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population Ke T, Dorajoo R, Han Y, Khor CC, van Dam RM, Yuan JM, Koh WP, Liu J, Teo YY, Goh DY, Tai ES, Wong TY, Cheng CY, Friedlander Y, Heng CK Ann Hum Genet. 2016 Sep;80(5):282-93
- Vitamin D insufficiency and cognitive impairment in Asians: A multi-ethnic population-based study and meta-analysis Annweiler C, Milea D, Whitson HE, Cheng CY, Wong TY, Ikram MK, Lamoureux EL, Sabanayagam C J Intern Med. 2016 Sep;280(3):300-11
- Association of Vision Impairment and Major Eye Diseases With Mobility and Independence in a Chinese Population Fenwick EK, Ong PG, Man RE, Cheng CY, Sabanayagam C, Wong TY, Lamoureux EL JAMA Ophthalmol. 2016 Oct 1;134(10):1087-1093
- Visual Impairment in Old and Very Old Community-dwelling Asian Adults Sabanayagam C, Fenwick E, Ong PG, Tey ML, Tapp R, Cheng CY, Cheung GC, Aung T, Wong TY, Lamoureux EL Ophthalmology. 2016 Nov;123(11):2436-2438
- Association of Changes in Visual Acuity With Vision-Specific Functioning in the Singapore Malay Eye Study Fenwick EK, Man RE, Ong PG, Sabanayagam C, Gupta P, Cheng CY, Wong TY, Lamoureux EL JAMA Ophthalmol. 2016 Nov 1;134(11):1299-1305
- Cost-effectiveness of a National Telemedicine Diabetic Retinopathy Screening Program in Singapore Nguyen HV, Tan GS, Tapp RJ, Mital S, Ting DS, Wong HT, Tan CS, Laude A, Tai ES, Tan NC, Finkelstein EA, Wong TY, Lamoureux EL Ophthalmology. 2016 Dec;123(12):2571-2580
- Type 2 Diabetes Genetic Variants and Risk of Diabetic Retinopathy Chong YH, Fan Q, Tham YC, Gan A, Tan SP, Tan G, Wang JJ, Mitchell P, Wong TY, Cheng CY Ophthalmology. 2016 Dec 27. pii: S0161-6420(16)30930-7. doi: 10.1016/j.ophtha.2016.11.016. [Epub ahead of print]
2015
- Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polašek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MK, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X,Teo YY, Tai ES, Vithana E, Barathi V, Zheng Y, Siantar RG, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimäki T, Kähönen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Pärssinen O, Stambolian D, Hammond CJ, Klaver CC, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA; The CREAM Consortium Hum Genet. 2015 Feb; 134(2):131-46
- Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract Liao J, Su X, Chen P, Wang X, Xu L, Li X, Thean L, Tan C, Tan AG, Tay WT, Jun G, Zheng Y, Chew M, Wang YX, Tan QS, Barathi VA, Klein BE, Saw SM, Vithana EN,Tai ES, Iyengar SK, Mitchell P, Khor CC, Aung T, Wang JJ, Jonas JB, Teo YY, Wong TY, Cheng CY Hum Mol Genet. 2015 Feb; 100(2):689-96
- Serum leptin and age-related macular degeneration Seshasai S, Liao J, Toh QC, Cheng CY, Cheung CM, Sethi S, Wong TY, Sabanayagam C Invest Ophthalmol Vis Sci. 2015 Feb; 56(3):1880-6
- Body mass index and retinopathy in Asian populations with diabetes mellitus Rooney D, Lye WK, Tan G, Lamoureux EL, Ikram MK, Cheng CY, Kumari N, Zheng YF, Mitchell P, Wang JJ, Wong TY, Sabanayagam C Acta Diabetol. 2015 Feb; 52(1):73-80
- Diagnosis of Diabetes Mellitus using HbA1c in Asians: Relationship between HbA1c and Retinopathy in a Multi-Ethnic Asian Population Sabanayagam C, Khoo EY, Lye WK, Ikram MK, Lamoureux EL, Cheng CY, Tan ML, Salim A, Lee JJ, Lim SC, Tavintharan S, Thai AC, Heng D, Ma S, Tai ES, Wong TY J Clin Endocrinol Metab. 2015 Feb; 100(2):689-96
- Distribution and determinants of choroidal thickness and volume using automated segmentation software in a population-based study Gupta P, Jing T, Marziliano P, Cheung CY, Baskaran M, Lamoureux EL, Wong TY, Cheung CM, Cheng CY Am J Ophthalmol. 2015 Feb; 159(2):293-301.e3
- Retinal neurodegeneration on optical coherence tomography and cerebral atrophy Ong YT, Hilal S, Cheung CY, Venketasubramanian N, Niessen WJ, Vrooman H, Anuar AR, Chew M, Chen C, Wong TY, Ikram MK Neurosci Lett. 2015 Jan 1; 584:12-6
- Retinal microvascular abnormalities and risk of renal failure in Asian populations Yip W, Sabanayagam C, Teo BW, Tay WT, Ikram MK, Tai ES, Chow KY, Wong TY, Cheung CY PLoS One. 2015 Feb 6; 10(2):e0118076
- Diagnosis of diabetes mellitus using HbA1c in Asians: relationship between HbA1c and retinopathy in a multiethnic Asian population Sabanayagam C, Khoo EY, Lye WK, Ikram MK, Lamoureux EL, Cheng CY, Tan ML, Salim A, Lee J, Lim SC, Tavintharan S, Thai AC, Heng D, Ma S, Tai ES, Wong TY J Clin Endocrinol Metab. 2015 Feb; 100(2):689-96
- Lens status influences the association between CFH polymorphisms and age-related macular degeneration: findings from two population-based studies in Singapore Wong CW, Wong TY, Liao J, Cheung GC, Khor CC, Vithana EN, Wang JJ, Mitchell P, Aung T, Cheng CY PLoS One. 2015 Mar;10(3):e0119570
- Retinal ganglion cell analysis using high-definition optical coherence tomography in patients with mild cognitive impairment and Alzheimer’s disease Cheung CY, Ong YT, Hilal S, Ikram MK, Low S, Ong YL, Venketasubramanian N, Yap P, Seow D, Chen CL, Wong TY J Alzheimers Dis. 2015; 45(1):45-56
- Polypoidal Choroidal Vasculopathy in Asians Wong CW, Wong TY, Cheung CM J Clin Med. 2015 Apr 24; 4(5):782-821
- The clinical implications of recent studies on the structure and function of the retinal microvasculature in diabetes Cheung CY, Ikram MK, Klein R, Wong TY Diabetologia. 2015 May; 58(5):871-85
- Determinants of optical coherence tomography-derived minimum neuroretinal rim width in a normal Chinese population Tun TA, Sun CH, Baskaran M, Girard MJ, de Leon JM, Cheng CY, Htoon HM, Wong TY, Aung T, Strouthidis NG Invest Ophthalmol Vis Sci. 2015 May; 56(5):3337-44
- Relationship of Intraocular Pressure with Central Aortic Systolic Pressure Tsai AS, Aung T, Yip W, Wong TY, Cheung CY Curr Eye Res. 2015 May 5:1-6
- A global shape index to characterize anterior lamina cribrosa morphology and its determinants in healthy Indian eyes Thakku SG, Tham YC, Baskaran M, Mari JM, Strouthidis NG, Aung T, Cheng CY, Girard MJ Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):3604-14
- Aggregate effects of intraocular pressure and cup-to-disc ratio genetic variants on glaucoma in a multiethnic Asian population Tham YC, Liao J, Vithana EN, Khor CC, International Glaucoma Genetics Consortium, Teo YY, Tai ES, Wong TY, Aung T, Cheng CY Ophthalmology. 2015 Jun; 122(6):1149-57
- Peripapillary choroidal thickness assessed using automated choroidal segmentation software in an Asian population Gupta P, Jing T, Marziliano P, Baskaran M, Cheung GC, Lamoureux EL, Cheung CY, Wong TY, Aung T, Cheng CY Br J Ophthalmol. 2015 Jul; 99(7):920-6
- The Prevalence and Types of Glaucoma in an Urban Chinese Population: The Singapore Chinese Eye Study Baskaran M, Foo RC, Cheng CY, Narayanaswamy AK, Zheng YF, Wu R, Saw SM, Foster PJ, Wong TY, Aung T JAMA Ophthalmol. 2015 Aug; 133(8):874-80
- A Prospective Cohort study in a Multi-ethnic Asian population Lim CC, Teo BW, Ong PG, Cheung CY, Lim SC, Chow KY, Meng CC, Lee J, Tai ES, Wong TY, Sabanayagam C Eur J Prev Cardiol. 2015 Aug; 22(8):1018-26
- Prevalence, risk factors and visual features of undiagnosed glaucoma: the Singapore Epidemiology of Eye Diseases Studies Chua J, Baskaran M, Ong PG, Zheng Y, Wong TY, Aung T, Cheng CY JAMA Ophthalmol. 2015 Aug; 133(8):938-46
- Ocular Fundus Photography as a Tool to Study Stroke and Dementia Cheung CY, Chen C, Wong TY Semin Neurol. 2015 Oct;35(5):481-90
- Ancestry, socioeconomic status, and age-related cataract in Asians: the Singapore Epidemiology of Eye Diseases Study Chua J, Koh JY, Tan AG, Zhao W, Lamoureux E, Mitchell P, Wang JJ, Wong TY, Cheng CY Ophthalmology. 2015 Nov; 122(11):2169-78
- Impact of Visual Impairment and Eye diseases on Mortality: the Singapore Malay Eye Study (SiMES) Siantar RS, Cheng CY, Cheung GC, Lamoureux E, Ong PG, Chow KY, Mitchell P, Aung T, Wong TY, Cheung CY Sci Rep. 2015 Nov; 5:16304
- Composite measures of individual and area-level socio-economic status are associated with visual impairment in Singapore Wah W, Earnest A, Sabanayagam C, Cheng CY, Ong M, Wong TY, Lamoureux EL PLoS One. 2015 Nov; 10(11):e0142302
- Markers of Chronic Kidney Disease and Retinopathy in persons with Diabetes Wong CW, Teo BW, Lamoureux E, Ikram MK, Wang JJ, Tai ES, Sethi S, Wong TY, Sabanayagam C J Diabetes Res. 2015; 2015:404280
- Prevalence and determinants of undiagnosed diabetic retinopathy and vision-threatening retinopathy in a multiethnic Asian cohort: the Singapore Epidemiology of Eye Diseases (SEED) study Huang OS, Tay WT, Ong PG, Sabanayagam C, Cheng CY, Tan GS, Cheung GC, Lamoureux EL, Wong TY Br J Ophthalmol. 2015 Dec; 99(12):1614-21
2014
- Impact of measurement error on testing genetic association with quantitative traits Liao J, Li X, Wong TY, Wang JJ, Khor CC, Tai ES, Aung T, Teo YY, Cheng CY PLoS One. 2014 Jan; 9(1):e87044
- Retinal vascular fractal dimension is associated with cognitive dysfunction Cheung CY, Ong S, Ikram MK, Ong YT, Chen CP, Venketasubramanian N, Wong TY J Stroke Cerebrovasc Dis. 2014 Jan; 23(1):43-50
- Retinal Microvasculature in Alzheimer’s disease Cheung CY, Ong YT, Ikran MK, Chen CP, Wong TY Journal of Alzheimer’s Disease. 2014 Jan 1;42(0):S339-52
- Education influences the association between genetic variants and refractive error: a meta-analysis of five Singapore studies Fan Q, Wojciechowski R, Ikram MK, Cheng CY, Chen P, Zhou X, Pan CW, Khor CC, Tai ES, Aung T, Wong TY, Teo YY, Saw SM Hum Mol Genet. 2014 Jan; 23(2):546-554
- Ethnic differences in undercorrected refractive error in Asians Pan CW, Chiang PP, Wong TY, Zheng YF, Chew M, Saw SM, Lamoureux EL, Cheng CY Optom Vis Sci. 2014 Feb; 91(2):212-20
- Marital status and its relationship with the risk and pattern of visual impairment in a multi-ethnic Asian population Zheng Y, Lamoureux EL, Chiang PP, Rahman Anuar A, Wong TY J Public Health (Oxf). 2014 Mar; 36(1):104-10
- ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma Nongpiur ME, Khor CC, Jia H, Cornes BK, Chen LJ, Qiao C, Nair KS, Cheng CY, Xu L, George R, Tan D, Abu-Amero K, Perera SA, Ozaki M, Mizoguchi T, Kurimoto Y, Low S, Tajudin LS, Ho CL, Tham CC, Soto I, Chew PT, Wong HT, Shantha B, Kuroda M, Osman EA, Tang G, Fan S, Meng H, Wang H, Feng B, Yong VH, Ting SM, Li Y, Wang YX, Li Z, Lavanya R, Wu RY, Zheng YF, Su DH, Loon SC, Yong VK, Allingham RR, Hauser MA, Soumittra N, Ramprasad VL, Waseem N, Yaakub A, Chia KS, Kumaramanickavel G, Wong TT, How AC, Chau TN, Simmons CP, Bei JX, Zeng YX, Bhattacharya SS, Zhang M, Tan DT, Teo YY, Al-Obeidan SA, Hon do N, Tai ES, Saw SM, Foster PJ, Vijaya L, Jonas JB, Wong TY, John SW, Pang CP, Vithana EN, Wang N, Aung T PLoS Genet. 2014 Mar 6; 10(3):e1004089
- Ethnic variation in central corneal refractive power and steep cornea in Asians Pan CW, Cheng CY, Sabanayagam C, Chew M, Lam J, Ang M, Wong TY Ophthalmic Epidemiol. 2014 Apr; 21(2):99-105
- Female reproductive factors and major eye diseases in Asian women – the Singapore Malay Eye Study Lam JS, Tay WT, Aung T, Saw SM, Wong TY Ophthalmic Epidemiol. 2014 Apr; 21(2):92-8
- Assessment of iris surface features and their relationship with iris thickness in Asian eyes Sidhartha E, Gupta P, Liao J, Tham YC, Cheung CY, He M, Wong TY, Aung T, Cheng CY Ophthalmology. 2014 May; 121(5):1007-12
- A simplified method to measure choroidal thickness using adaptive compensation in enhanced depth imaging optical coherence tomography Wong WL, Su X, Li X, Cheung CM, Klein R, Cheng CY, Wong TY. PLoS One. 2014 May 5; 9(5):e96661
- Ethnic variation in early age-related macular degeneration lesions between white Australians and Singaporean Asians Joachim N, Mitchell P, Younan C, Burlutsky G, Cheng CY, Cheung CM, Zheng Y, Moffitt M, Wong TY, Wang JJ Invest Ophthalmol Vis Sci. 2014 Jun 26; 55(7):4421-9
- Kidney and Eye Diseases: Common Risk Factors, Etiological mechanisms and Pathways Wong CW, Wong TY, Cheng CY, Sabanayagam C Kidney International. 2014 Jun; 85(6):1290-302
- Forecasting the burden of type 2 diabetes in Singapore using a demographic epidemiological model of Singapore Phan TP, Alkema L, Tai ES, Tan KHX, Yang Q, Lim WY, Teo YY, Cheng CY, Wang X, Wong TY, Chia KS, Cook AR BMJ Open Diabetes Res Care. 2014 Jun; 2(1):e000012
- Ethnic variation in early age-related macular degeneration lesions between white Australians and Singaporean Asians Joachim N, Mitchell P, Younan C, Burlutsky G, Cheng CY, Cheung CM, Zheng Y, Moffitt M, Wong TY, Wang JJ Invest Ophthalmol Vis Sci. 2014 Jun 26; 55(7):4421-9
- Sectoral variations of iridocorneal angle width and iris volume in Chinese Singaporeans: a swept-source optical coherence tomography study Tun TA, Baskaran M, Perera SA, Chan AS, Cheng CY, Htoon HM, Sakata LM, Cheung CY, Aung T Graefes Arch Clin Exp Ophthalmol. 2014 Jul; 252(7):1127-32
- Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC; LifeLines Cohort Study, Lluís-Ganella C, Luan J, Lyytikäinen LP, Nolte IM, Sim X, Sõber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kähönen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Völker U, Völzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimäki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC Am J Hum Genet. 2014 Jul 3; 95(1):24-3
- Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians Chen P, Takeuchi F, Lee JY, Li H, Wu JY, Liang J, Long J, Tabara Y, Goodarzi MO, Pereira MA, Kim YJ, Go MJ, Stram DO, Vithana E, Khor CC, Liu J, Liao J, Ye X, Wang Y, Lu L, Young TL, Lee J, Thai AC, Cheng CY, van Dam RM, Friedlander Y, Heng CK, Koh WP, Chen CH, Chang LC, Pan WH, Qi Q, Isono M, Zheng W, Cai Q, Gao Y, Yamamoto K, Ohnaka K, Takayanagi R, Kita Y, Ueshima H, Hsiung CA, Cui J, Sheu WH, Rotter JI, Chen YD, Hsu C, Okada Y, Kubo M, Takahashi A, Tanaka T, van Rooij FJ, Ganesh SK, Huang J, Huang T, Yuan J, Hwang JY; CHARGE Hematology Working Group, Gross MD, Assimes TL, Miki T, Shu XO, Qi L, Chen YT, Lin X, Aung T, Wong TY, Teo YY, Kim BJ, Kato N, Tai ES Diabetes. 2014 Jul; 63(7):2551-62
- Accounting for standard errors of vision-specific latent trait in regression models Wong WL, Li X, Li J, Wong TY, Cheng CY, Lamoureux EL. Ophthalmol Vis Sci. 2014 Jul 11; 55(9):5848-54
- Prevalence, racial variations, and risk factors of age-related macular degeneration in Singaporean Chinese, Indians, and Malays Cheung CM, Li X, Cheng CY, Zheng Y, Mitchell P, Wang JJ, Wong TY Ophthalmology. 2014 Aug; 121(8):1598-603
- Retinal Vascular Caliber and Age-related Macular Degeneration in an Indian Population from Singapore Chin YC, Wong TY, Cheung CM, Cheung CY, Zheng Y, Mitchell P, Huang H, Wang JJ, Ikram MK Ophthalmic Epidemiol. 2014 Aug; 21(4):224-9
- Microvascular network alterations in retina of subjects with cerebral small vessel disease Hilal S, Ong YT, Cheung CY, Tan CS, Venketasubramanian N, Niessen WJ, Vrooman H, Anuar AR, Chew M, Chen C, Wong TY, Ikram MK Neurosci Lett. 2014 Aug 8; 577:95-100
- Retinal vascular fractals and cognitive impairment Ong YT, Hilal S, Cheung CY, Xu X, Chen C, Venketasubramanian N, Wong TY, Ikram MK Dement Geriatr Cogn Dis Extra. 2014 Aug 27; 4(2):305-13
- Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, Xu L, Mountain JE, Gharahkhani P, Lu Y, Amin N, Karssen LC, Sim KS, van Leeuwen EM, Iglesias AI, Verhoeven VJ, Hauser MA, Loon SC, Despriet DD, Nag A, Venturini C, Sanfilippo PG, Schillert A, Kang JH, Landers J, Jonasson F, Cree AJ, van Koolwijk LM, Rivadeneira F, Souzeau E, Jonsson V, Menon G; Blue Mountains Eye Study—GWAS group, Weinreb RN, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Ennis S, Thorsteinsdottir U, Burdon KP; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Spector TD, Mirshahi A, Saw SM, Vingerling JR, Teo YY, Haines JL, Wolfs RC, Lemij HG, Tai ES, Jansonius NM, Jonas JB, Cheng CY, Aung T, Viswanathan AC, Klaver CC, Craig JE, Macgregor S, Mackey DA, Lotery AJ, Stefansson K, Bergen AA, Young TL, Wiggs JL, Pfeiffer N, Wong TY, Pasquale LR, Hewitt AW, van Duijn CM, Hammond CJ Nat Commun. 2014 Sep 22; 5:4883
- Health Burden Associated with Visual Impairment in Singapore: The Singapore Epidemiology of Eye Disease Study Wang X, Lamoureux E, Zheng Y, Ang M, Wong TY, Luo N Ophthalmology. 2014 Sep; 121(9):1837-42
- Genetic Determinants of Age-Related Macular Degeneration in Diverse Populations From the PAGE Study Restrepo NA, Spencer KL, Goodloe R, Garrett TA, Heiss G, B?žková P, Jorgensen N, Jensen RA, Matise TC, Hindorff LA, Klein BE, Klein R, Wong TY, Cheng CY, Cornes BK, Tai ES, Ritchie MD, Haines JL, Crawford DC Invest Ophthalmol Vis Sci. 2014 Sep 9; 55(10):6839-50
- Ethnic Differences of Intraocular Pressure and Central Corneal Thickness: The Singapore Epidemiology of Eye Diseases Study Chua J, Tham YC, Liao J, Zheng Y, Aung T, Wong TY, Cheng CY Ophthalmology. 2014 Oct; 121(10):2013-22
- Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JN, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, Khor CC, Stefansson AB, Liao J, Haines JL, Amin N, Wang YX, Wild PS, Ozel AB, Li JZ, Fleck BW, Zeller T, Staffieri SE, Teo YY, Cuellar-Partida G, Luo X, Allingham RR, Richards JE, Senft A, Karssen LC, Zheng Y, Bellenguez C, Xu L, Iglesias AI, Wilson JF, Kang JH, van Leeuwen EM, Jonsson V, Thorsteinsdottir U, Despriet DD, Ennis S, Moroi SE, Martin NG, Jansonius NM, Yazar S, Tai ES, Amouyel P, Kirwan J, van Koolwijk LM, Hauser MA, Jonasson F, Leo P, Loomis SJ, Fogarty R, Rivadeneira F, Kearns L, Lackner KJ, de Jong PT, Simpson CL, Pennell CE, Oostra BA, Uitterlinden AG, Saw SM, Lotery AJ, Bailey-Wilson JE, Hofman A, Vingerling JR, Maubaret C, Pfeiffer N, Wolfs RC, Lemij HG, Young TL, Pasquale LR, Delcourt C, Spector TD, Klaver CC, Small KS, Burdon KP, Stefansson K, Wong TY; BMES GWAS Group; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2, Viswanathan A, Mackey DA, Craig JE, Wiggs JL, van Duijn CM, Hammond CJ, Aung T Nat Genet. 2014 Oct; 46(10):1126-30
- Relationship between Iris Surface Features and Angle Width in Asian Eyes Sidhartha E, Nongpiur ME, Cheung CY, He MG, Wong TY, Aung T, Cheng CY Invest Ophthalmol Vis Sci. 2014 Oct 23; 55(12):8144-8
- CMPK1 and RBP3 are associated with corneal curvature in Asian populations Chen P, Miyake M, Fan Q, Liao J, Yamashiro K, Ikram MK, Chew M, Vithana EN, Khor CC, Aung T, Tai ES, Wong TY, Teo YY, Yoshimura N, Saw SM, Cheng CY Hum Mol Genet. 2014 Nov 15; 23(22):6129-36
- Choroidal thickness and high myopia: a case-control study of young Chinese men in Singapore Gupta P, Saw SM, Cheung CY, Girard MJ, Mari JM, Bhargava M, Tan C, Tan M, Yang A, Tey F, Nah G, Zhao P, Wong TY, Cheng CY Acta Ophthalmol. 2015 Nov; 93(7):e585-92
- Body mass index and preclinical kidney disease in Indian adults aged 40 years and above without chronic kidney disease Sabanayagam C, Wong TY, Liao J, Sethi S, Teo BW Clin Exp Nephrol. 2014 Dec; 18(6):919-24
- Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study Cheng CY, Allingham RR, Aung T, Tham YC, Hauser MA, Vithana EN, Khor CC, Wong TY Invest Ophthalmol Vis Sci. 2014 Dec 23; 56(1):478-83
- Prevalence and risk factors for retinopathy in persons without diabetes: the Singapore Indian Eye Study Bhargava M, Cheung CY, Sabanayagam C, Huang L, Lamoureux EL, Wang JJ, Tai ES, Heng CK, Ikram MK, Mitchell P, Wong TY Acta Ophthalmol. 2014 Dec; 92(8):e602-9
- Comparison of CKD-EPI cystatin C and creatinine glomerular filtration rate estimation equations in Asian-Indians Teo BW, Sabanayagam C, Liao J, Toh QC, Saw S, Wong TY, Sethi S Int J Nephrol. 2014; 2014:746497
2013
- Retinal vascular geometry and glaucoma: the Singapore Malay Eye Study Wu R, Cheung CY, Saw SM, Mitchell P, Aung T, Wong TY Ophthalmology. 2013 Jan; 120(1):77-83
- Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis Holliday EG, Smith AV, Cornes BK, Buitendijk GH, Jensen RA, Sim X, Aspelund T, Aung T, Baird PN, Boerwinkle E, Cheng CY, van Duijn CM, Eiriksdottir G, Gudnason V, Harris T, Hewitt AW, Inouye M, Jonasson F, Klein BE, Launer L, Li X, Liew G, Lumley T, McElduff P, McKnight B, Mitchell P, Psaty BM, Rochtchina E, Rotter JI, Scott RJ, Tay W, Taylor K, Teo YY, Uitterlinden AG, Viswanathan A, Xie S, Wellcome Trust Case Control C, Vingerling JR, Klaver CC, Tai ES, Siscovick D, Klein R, Cotch MF, Wong TY, Attia J, Wang JJ PLoS One. 2013 Jan; 8(1):e53830
- Myopia and cognitive dysfunction: the Singapore Malay Eye Study Ong SY, Ikram MK, Haaland BA, Cheng CY, Saw SM, Wong TY, Cheung CY Invest Ophthalmol Vis Sci. 2013 Jan 28; 54(1):799-803
- Cataract conversion assessment using lens opacity classification system III and Wisconsin cataract grading system Wong WL, Li X, Li J, Cheng CY, Lamoureux EL, Wang JJ, Cheung CY, Wong TY Invest Ophthalmol Vis Sci. 2013 Jan; 54(1):280-287
- Asian Age-Related Macular Degeneration: Current Concepts and Gaps in Knowledge Lim LS, Cheung CM, Wong TY Asia Pac J Ophthalmol (Phila). 2013 Jan-Feb; 2(1):32-41
- Frequency and risk factors of non-retinopathy ocular conditions in people with diabetes: the Singapore Malay Eye Study Chiang PP, Lamoureux EL, Zheng Y, Tay WT, Mitchell P, Wang JJ, Wong TY Diabet Med. 2013 Feb; 30(2):e32-40
- Differential associations of myopia with major age-related eye diseases: the Singapore Indian Eye Study Pan CW, Cheung CY, Aung T, Cheung CM, Zheng YF, Wu RY, Mitchell P, Lavanya R, Baskaran M, Wang JJ, Wong TY, Saw SM Ophthalmology. 2013 Feb; 120(2):284-91
- Impact of glaucoma severity and laterality on vision-specific functioning: the Singapore Malay Eye study Chan EW, Chiang PP, Wong TY, Saw SM, Loon SC, Aung T, Lamoureux E Invest Ophthalmol Vis Sci. 2013 Feb 1; 54(2):1169-75
- Vision impairment and major causes of vision loss impacts on vision-specific functioning independent of socioeconomic factors Chiang PP, Zheng Y, Wong TY, Lamoureux EL Ophthalmology. 2013 Feb; 120(2):415-22
- How Much Eye Care Services Do Asian Populations Need? Projection from the Singapore Epidemiology of Eye Disease (SEED) Study Zheng Y, Cheng CY, Lamoureux EL, Chiang PP, Rahman Anuar A, Wang JJ, Mitchell P, Saw SM, Wong TY Invest Ophthalmol Vis Sci. 2013 Mar 1; 54(3):2171-7
- Coordinated genetic scaling of the human eye: shared determination of axial eye length and corneal curvature Guggenheim JA, Zhou X, Evans DM, Timpson NJ, McMahon G, Kemp JP, St Pourcain B, Northstone K, Ring SM, Fan Q, Wong TY, Cheng CY, Khor CC, Aung T, Saw SM, Williams C Invest Ophthalmol Vis Sci. 2013 Mar 7; 54(3):1715-21
- Genome-wide meta-analyses of multi-ancestry cohorts identify multiple new susceptibility loci for refractive error and myopia Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, Pourcain BS, Simpson CL, Mäkelä KM, Lehtimäki T, Kähönen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Pärssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BE, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA; Consortium for Refractive Error and Myopia (CREAM), Chen P, Li R, Liao J, Zheng Y, Ong RT, Döring A; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Evans DM, Timpson NJ, Verkerk AJ, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W; Wellcome Trust Case Control Consortium 2 (WTCCC2), Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasatian S, Igo RP Jr, Lass JH, Chew E, Iyengar SK; Fuchs’ Genetics Multi-Center Study Group, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ Nat Genet. 2013 Mar; 45(3):314-8
- Prevalence of refractive errors in a multiethnic Asian population: the Singapore Epidemiology of Eye Disease Study Pan CW, Zheng YF, Anuar AR, Chew M, Gazzard G, Aung T, Cheng CY, Wong TY, Saw SM Invest Ophthalmol Vis Sci. 2013 Apr 9; 54(4):2590-8
- Associations of iris structural measurements in a chinese population: the Singapore Chinese Eye Study Sng CC, Allen JC, Nongpiur ME, Foo LL, Zheng Y, Cheung CY, He M, Friedman DS, Wong TY, Aung T Invest Ophthalmol Vis Sci. 2013 Apr 23; 54(4):2829-35
- Structural Changes in the Retinal Microvasculature and Renal Function Lim L, Cheung CY, Sabanayagam C, Lim SC, Tai ES, Lei H, Wong TY Invest Ophthalmol Vis.Sci. 2013 Apr 26; 54(4):2970-6
- Ethnic variation in the impact of metabolic syndrome components and chronic kidney disease Sabanayagam C, Teo BW, Tai ES, Jafar TH, Wong TY Maturitas. 2013 Apr; 74(4):369-74
- Prevalence and risk factors for age-related macular degeneration in Indians: a comparative study in Singapore and India Cheung CM, Li X, Cheng CY, Zheng Y, Mitchell P, Wang JJ, Jonas JB, Nangia, Wong TY Am J Ophthalmol. 2013 Apr; 155(4):764-773
- Ethnic variations in the impact of metabolic syndrome components and chronic kidney disease Sabanayagam C, Teo BW, Tai ES, Jafar TH, Wong TY Maturitas. 2013 Apr; 74(4):369-74
- Serum C-reactive protein level and prehypertension in two Asian populations Sabanayagam C, Shankar A, Lee J, Wong TY, Tai ES. J Hum Hypertens. 2013 Apr; 27(4):231-6
- Ethnic differences in the association between blood pressure components and chronic kidney disease in middle aged and older Asian adults Sabanayagam C, Teo BW, Tai ES, Jafar TH, Wong TY BMC Nephrol. 2013 Apr 17; 14:86
- Racial differences in retinal vessel geometric characteristics: a multiethnic study in healthy Asians Li X, Wong WL, Cheung CY, Cheng CY, Ikram MK, Li J, Chia KS, Wong TY Invest Ophthalmol Vis Sci. 2013 May 1; 54(5):3650-6
- Branch retinal vein occlusion and optic nerve head topographic parameters: the Singapore Indian Eye Study Chan EW, Wong TY, Liao J, Cheung CY, Zheng YF, Wang JJ, Mitchell P, Loon SC, Saw SM, Aung T, Cheng CY Br J Ophthalmol. 2013 May; 97(5):611-6
- Prevalence of cognitive impairment in Chinese: Epidemiology of Dementia in Singapore study Hilal S, Ikram MK, Saini M, Tan CS, Catindig JA, Dong YH, Lim LB, Ting EY, Koo EH, Cheung CY, Qiu A, Wong TY, Chen CL, Venketasubramanian N J Neurol Neurosurg Psychiatry. 2013 Jun; 84(6):686-92
- Is aspirin intake associated with early age-related macular degeneration? The Singapore Indian Eye Study Cheung N, Tay WT, Cheung GC, Wang JJ, Mitchell P, Wong TY Br J Ophthalmol. 2013 Jun; 97(6):785-8
- Superpixel classification based optic disc and optic cup segmentation for glaucoma screening Cheng J, Liu J, Xu Y, Yin F, Wong DW, Tan NM, Tao D, Cheng CY, Aung T, Wong TY IEEE Trans Med Imaging. 2013 Jun; 32(6):1019-32
- The prevalence and types of glaucoma in an urban Indian population: the Singapore Indian Eye Study Narayanaswamy A, Baskaran M, Zheng Y, Lavanya R, Wu R, Wong WL, Saw SM, Cheng CY, Wong TY, Aung T Invest Ophthalmol Vis Sci. 2013 Jul 10; 54(7):4621-7
- Myopia, axial length, and age-related cataract: the Singapore Malay Eye Study Pan CW, Boey PY, Cheng CY, Saw SM, Tay WT, Wang JJ, Tan AG, Mitchell P, Wong TY Invest Ophthalmol Vis Sci. 2013 Jul 2; 54(7):4498-502
- Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? Dorajoo R, Li R, Ikram MK, Liu J, Froguel P, Lee J, Sim X, Ong RT, Tay WT, Peng C, Young TL, Blakemore AI, Cheng CY, Aung T, Mitchell P, Wang JJ, Klaver CC, Boerwinkle E, Klein R, Siscovick DS, Jensen RA, Gudnason V, Smith AV, Teo YY, Wong TY, Tai ES, Heng CK, Friedlander Y PLoS One. 2013 Jul 2; 8(7):e67650
- Prevalence, awareness, and control of hypertension among Asian Indians living in urban Singapore and rural India Yip W, Wong TY, Jonas JB, Zheng Y, Lamoureux EL, Nangia V, Sabanayagam C J Hypertens. 2013 Aug; 31(8):1539-46
- Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M; Consortium for Refractive Error and Myopia, Burdon KP, Craig JE, Iyengar SK, Igo RP Jr, Lass JH Jr; Fuchs’ Genetics Multi-Center Study Group, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ; Wellcome Trust Case Control Consortium 2, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN Am J Hum Genet. 2013 Aug 8; 93(2):264-77
- Familial correlation of retinal vascular caliber in Singapore Chinese Li LJ, Liao J, Fan Q, Cheung CY, Ikram MK, Cheng CY, Saw SM, Wong TY Invest Ophthalmol Vis Sci. 2013 Aug 19; 54(8):5638-42
- Lack of association between primary angle-closure glaucoma susceptibility loci and the ocular biometric parameters anterior chamber depth and axial length Nongpiur ME, Wei X, Xu L, Perera SA, Wu RY, Zheng Y, Li Y, Wang YX, Cheng CY, Jonas JB, Wong TY, Vithana EN, Aung T, Khor CC Invest Ophthalmol Vis Sci. 2013 Aug 27; 54(8):5824-8
- Diagnostic Performance of the ISNT Rule for Glaucoma Based on the Heidelberg Retinal Tomograph Chan EW, Liao J, Wong R, Loon SC, Aung T, Wong TY, Cheng CY Transl Vis Sci Technol. 2013 Aug; 2(5):2
- Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular disease Chiang PP, Lamoureux EL, Shankar A, Tai ES, Wong TY, Sabanayagam C BMC Public Health. 2013 Aug 7; 13(1):730
- Retinal Microvascular Changes and Risk of Stroke: The Singapore Malay Eye Study Cheung CY, Tay WT, Ikram MK, Ong YT, De Silva DA, Chow KY, Wong TY Stroke. 2013 Sep; 44(9):2402-2408
- Prevalence of Cataract Surgery and Visual Outcomes in Indian Immigrants in Singapore: The Singapore Indian Eye Study Gupta P, Zheng Y, Ting TW, Lamoureux EL, Cheng CY, Wong TY PLoS One. 2013 Oct 7; 8(10):e75584
- Refractive Errors and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis Pan CW, Ikram MK, Cheung CY, Choi HW, Cheung CM, Jonas JB, Saw SM, Wong TY Ophthalmology. 2013 Oct; 120(10):2058-2065
- Relationship between retinal vascular geometry with retinal nerve fiber layer and ganglion cell-inner plexiform layer in nonglaucomatous eyes Tham YC, Cheng CY, Zheng Y, Aung T, Wong TY, Cheung CY Invest Ophthalmol Vis Sci. 2013 Nov 5; 54(12):7309-16
- Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. Kelly TN, Takeuchi F, Tabara Y, Edwards TL, Kim YJ, Chen P, Li H, Wu Y, Yang CF, Zhang Y, Gu D, Katsuya T, Ohkubo T, Gao YT, Go MJ, Teo YY, Lu L, Lee NR,Chang LC, Peng H, Zhao Q, Nakashima E, Kita Y, Shu XO, Kim NH, Tai ES, Wang Y, Adair LS, Chen CH, Zhang S, Li C, Nabika T, Umemura S, Cai Q, Cho YS, Wong TY, Zhu J, Wu JY, Gao X, Hixson JE, Cai H, Lee J, Cheng CY, Rao DC, Xiang YB, Cho MC, Han BG, Wang A, Tsai FJ, Mohlke K, Lin X, Ikram MK, Lee JY, Zheng W, Tetsuro M, Kato N, He J Hypertension. 2013 Nov;62(5):853-9
- A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry Chen P, Ong RT, Tay WT, Sim X, Ali M, Xu H, Suo C, Liu J, Chia KS, Vithana E, Young TL, Aung T, Lim WY, Khor CC, Cheng CY, Wong TY, Teo YY, Tai ES PLoS One. 2013 Nov; 8(11):e79767
- Myopia and age-related cataract: a systematic review and meta-analysis Pan CW, Cheng CY, Saw SM, Wang JJ, Wong TY Am J Ophthalmol. 2013 Nov; 156(5):1021-1033
- The economic cost of myopia in adults aged over 40 years in Singapore Zheng YF, Pan CW, Chay J, Wong TY, Finkelstein E, Saw SM Invest Ophthalmol Vis Sci. 2013 Nov 13; 54(12):7532-7
- Relationship between ganglion cell-inner plexiform layer and optic disc/retinal nerve fibre layer parameters in non-glaucomatous eyes Tham YC, Cheung CY, Koh VT, Cheng CY, Sidhartha E, Strouthidis NG, Wong TY, Aung T Br J Ophthalmol. 2013 Dec; 97(12):1592-7
- Validity of a new optic disc grading software for use in clinical and epidemiological research Tham YC, Cheung CY, Wong TY, Baskaran M, Liu J, Lee BH, Yin F, Wong DW, Wang JJ, Mitchell P, Aung T, Cheng CY Clin Experiment Ophthalmol. 2013 Dec; 41(9):842-52
- Determinants of macular thickness using spectral domain optical coherence tomography in healthy eyes: the Singapore Chinese Eye Study Gupta P, Sidhartha E, Tham YC, Chua DK, Liao J, Cheng CY, Aung T, Wong TY, Cheung CY Invest Ophthalmol Vis Sci. 2013 Dec 5; 54(13):7968-76
- Genome-wide association study of retinopathy in individuals without diabetes Jensen RA, Sim X, Li X, Cotch MF, Ikram MK, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BE, Launer LJ, Smith AV, Boerwinkle E, Cheung N, Hewitt AW, Liew G, Mitchell P, Wang JJ, Attia J, Scott R, Glazer NL, Lumley T, McKnight B, Psaty BM, Taylor K, Hofman A, de Jong PT, Rivadeneira F, Uitterlinden AG, Tay WT, Teo YY, Seielstad M, Liu J, Cheng CY, Saw SM, Aung T, Ganesh SK, O’Donnell CJ, Nalls MA, Wiggins KL, Kuo JZ; Blue Mountains Eye Study GWAS Team; CKDGen Consortium, van Duijn CM, Gudnason V, Klein R, Siscovick DS, Rotter JI, Tai ES, Vingerling J, Wong TY PLoS One. 2013; 8(2):e54232
- Lack of awareness of common eye conditions in the community Huang OS, Zheng Y, Tay WT, Chiang PP, Lamoureux EL, Wong TY Ophthalmic Epidemiol. 2013; 20(1):52-60
- Retinal vascular caliber measurements: clinical significance, current knowledge and future perspectives Ikram MK, Ong YT, Cheung CY, Wong TY Ophthalmologica. 2013; 229(3):125-36
2012
- Genetic variants on chromosome 1q41 influence ocular axial length and high myopia Fan Q, Barathi VA, Cheng CY, Zhou X, Meguro A, Nakata I, Khor CC, Goh LK, Li YJ, Lim W, Ho CE, Hawthorne F, Zheng Y, Chua D, Inoko H, Yamashiro K, Ohno-Matsui K, Matsuo K, Matsuda F, Vithana E, Seielstad M, Mizuki N, Beuerman RW, Tai ES, Yoshimura N, Aung T, Young TL, Wong TY, Teo YY, Saw SM PLoS Genet. 2012; 8(6):e1002753
- Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations Cornes BK, Khor CC, Nongpiur ME, Xu L, Tay WT, Zheng Y, Lavanya R, Li Y, Wu R, Sim X, Wang YX, Chen P, Teo YY, Chia KS, Seielstad M, Liu J, Hibberd ML, Cheng CY, Saw SM, Tai ES, Jonas JB, Vithana EN, Wong TY, Aung T Hum Mol Genet. 2012 Jan 15; 21(2):437-45
- Anterior segment optical coherence tomography study of the cornea and anterior segment in adult ethnic South Asian Indian eyes Ang M, Chong W, Tay WT, Yuen L, Wong TY, He MG, Saw SM, Aung T, Mehta JS Invest Ophthalmol Vis Sci. 2012 Jan 17; 53(1):120-5
- Review of key findings from the Singapore Malay Eye Study (SiMES-1) Rosman M, Zheng Y, Lamoureux E, Saw SM, Aung T, Tay WT, Wang JJ, Mitchell P, Tai ES, Wong TY Singapore Med J. 2012 Feb; 53(2):82-7
- How does hypertension affect your eyes? Bhargava M, Ikram MK, Wong TY J Hum Hypertens. 2012 Feb; 26(2):71-83
- Prevalence and risk factors of epiretinal membrane in Asian Indians Koh V, Cheung CY, Wong WL, Cheung CM, Wang JJ, Mitchell P, Younan C, Saw SM, Wong TY Invest Ophthalmol Vis Sci. 2012 Feb 27; 53(2):1018-22
- Determinants of angle width in Chinese Singaporeans Foo LL, Nongpiur ME, Allen JC, Perera SA, Friedman DS, He M, Cheng CY, Wong TY, Aung T Ophthalmology. 2012 Feb; 119(2):278-82
- Comparing stereometric parameters between heidelberg retinal tomography 2 and 3 in Asian eyes: the Singapore Malay Eye Study Wong WL, Wong TY, Aung T J Glaucoma. 2012 Feb; 21(2):102-6
- Global prevalence and major risk factors of diabetic retinopathy Yau JW, Rogers SL, Kawasaki R, Lamoureux EL, Kowalski JW, Bek T, Chen SJ, Dekker JM, Fletcher A, Grauslund J, Haffner S, Hamman RF, Ikram MK, Kayama T, Klein BE, Klein R, Krishnaiah S, Mayurasakorn K, O’Hare JP, Orchard TJ, Porta M, Rema M, Roy MS, Sharma T, Shaw J, Taylor H, Tielsch JM, Varma R, Wang JJ, Wang N, West S, Xu L, Yasuda M, Zhang X, Mitchell P, Wong TY, Meta-Analysis for Eye Disease Study Group Diabetes Care. 2012 Mar; 35(3):556-564
- Prevalence of and risk factors for age-related macular degeneration in a multiethnic Asian cohort Cheung CM, Li X, Cheng CY, Zheng Y, Mitchell P, Wang JJ, Wong TY Arch Ophthalmol. 2012 Apr; 130(4):480-6
- Early retinal arteriolar changes and peripheral neuropathy in diabetes Ding J, Cheung CY, Ikram MK, Zheng YF, Cheng CY, Lamoureux EL, Tai ES, Subramaniam T, Wong TY Diabetes Care. 2012 May; 35(5):1098-104
- Retinal vascular geometry in Asian persons with diabetes and retinopathy Cheung CY, Lamoureux E, Ikram MK, Sasongko MB, Ding J, Zheng Y, Mitchell P, Wang JJ, Wong TY J Diabetes Sci Technol. 2012 May 1; 6(3):595-605
- Influence of diabetes on macular thickness measured using optical coherence tomography: the Singapore Indian Eye Study Sng CC, Cheung CY, Man RE, Wong W, Lavanya R, Mitchell P, Aung T, Wong TY Eye (Lond). 2012 May; 26(5):690-8
- Determinants of anterior chamber depth: the Singapore Chinese Eye Study Sng CC, Foo LL, Cheng CY, Allen JC Jr, He M, Krishnaswamy G, Nongpiur ME, Friedman DS, Wong TY, Aung T Ophthalmology. 2012 Jun; 119(6):1143-50
- The impact of bilateral or unilateral cataract surgery on visual functioning: when does second eye cataract surgery benefit patients? Tan AC, Tay WT, Zheng YF, Tan AG, Wang JJ, Mitchell P, Wong TY, Lamoureux EL Br J Ophthalmol. 2012 Jun; 96(6):846-51
- Anterior chamber dimensions and posterior corneal arc length in Malay eyes: an anterior segment optical coherence tomography study Tan DK, Chong W, Tay WT, Yuen LH, He M, Aung T, Tan DT, Wong TY, Mehta JS Invest Ophthalmol Vis Sci. 2012 Jul 20; 53(8):4860-7
- Visual impairment, age-related eye diseases, and cognitive function: the Singapore Malay Eye study Ong SY, Cheung CY, Li X, Lamoureux EL, Ikram MK, Ding J, Cheng CY, Haaland BA, Saw SM, Venketasubramanian N, Chen CP, Wong TY Arch Ophthalmol. 2012 Jul; 130(7):895-900
- The impact of cataract, cataract types, and cataract grades on vision-specific functioning using Rasch analysis Chew M, Chiang PP, Zheng Y, Lavanya R, Wu R, Saw SM, Wong TY, Lamoureux EL Am J Ophthalmol. 2012 Jul; 154(1):29-38
- Singapore Malay Eye Study: rationale and methodology of 6-year follow-up study (SiMES-2) Rosman M, Zheng Y, Wong W, Lamoureux E, Saw SM, Tay WT, Wang JJ, Mitchell P, Tai ES, Wong TY Clin Experiment Ophthalmol. 2012 Aug; 40(6):557-68
- Current epidemiology of diabetic retinopathy and diabetic macular edema Ding J, Wong TY Curr Diab Rep. 2012 Aug; 12(4):346-54
- Prevalence of and racial differences in pterygium: a multiethnic population study in Asians Ang M, Li X, Wong W, Zheng Y, Chua D, Rahman A, Saw SM, Tan DT, Wong TY Ophthalmology. 2012 Aug; 119(8):1509-15
- Determinants of Ganglion Cell-Inner Plexiform Layer Thickness Measured by High-Definition Optical Coherence Tomography Koh VT, Tham YC, Cheung CY, Wong WL, Baskaran M, Saw SM, Wong TY, Aung T Invest Ophthalmol Vis Sci. 2012 Aug 24; 53(9):5853-9
- Variation in prevalence of myopia between generations of migrant Indians living in Singapore Pan CW, Zheng YF, Wong TY, Lavanya R, Wu RY, Gazzard G, Saw SM Am J Ophthalmol. 2012 Aug; 154(2):376-381
- Language barrier and its relationship to diabetes and diabetic retinopathy Zheng Y, Lamoureux EL, Chiang PC, Anuar AR, Ding J, Wang JJ, Mitchell P, Tai ES, Wong TY BMC Public Health. 2012 Sep 13; 12:781
- Prevalence and risk factors of diabetic retinopathy in migrant Indians in an urbanized society in Asia: the Singapore Indian Eye Study Zheng Y, Lamoureux EL, Lavanya R, Wu R, Ikram MK, Wang JJ, Mitchell P, Cheung N, Aung T, Saw SM, Wong TY Ophthalmology. 2012 Oct; 119(10):2119-24
- Retinal vascular fractal dimension and its relationship with cardiovascular and ocular risk factors Cheung CY, Thomas GN, Tay W, Ikram MK, Hsu W, Lee ML, Lau QP, Wong TY Am J Ophthalmol. 2012 Oct; 154(4):663-674
- Prevalence and risk factors of meibomian gland dysfunction: the Singapore Malay Eye Study Siak JJ, Tong L, Wong WL, Cajucom-Uy H, Rosman M, Saw SM, Wong TY Cornea. 2012 Nov; 31(11):1223-8
- Impacts of Migration and Acculturation on Prevalence of Type 2 Diabetes and related Eye Complications in Indians Living in a Newly Urbanised Society Zheng Y, Lamoureux EL, Ikram MK, Mitchell P, Wang JJ, Younan C, Anuar AR, Tai ES, Wong TY PLoS One. 2012; 7(4):e34829
- Prevalence of lens opacities in Asian Malays Tan AG, Tay WT, Mitchell P, Sandar M, Aung T, Saw SM, Wang JJ, Wong TY Ophthalmic Epidemiol. 2012 Dec; 19(6):380-7
2011
- Influence of refractive error and axial length on retinal vessel geometric characteristics Lim LS, Cheung CY, Lin X, Mitchell P, Wong TY, Mei-Saw S Invest Ophthalmol Vis Sci. 2011 Feb 3; 52(2):669-78
- Relationship of central corneal thickness with optic disc parameters: the Singapore Malay Eye Study Wu RY, Zheng YF, Wong TY, Cheung CY, Loon SC, Chauhan BC, Aung T Invest Ophthalmol Vis Sci. 2011 Mar 10; 52(3):1320-4
- Validity of a New Computer-Aided Diagnosis Imaging Program to Quantify Nuclear Cataract from Slit-lamp Photographs Cheung CY, Li H, Lamoureux EL, Mitchell P, Wang JJ, Tan AG, Johari LK, Liu J, Lim JH, Aung T, Wong TY Invest Ophthalmol Vis Sci. 2011 Mar 10; 52(3):1314-9
- Serum C-reactive protein level and prediabetes in two Asian populations Sabanayagam C, Shankar A, Lim SC, Lee J, Tai ES, Wong TY Diabetologia. 2011 Apr; 54(4):767-75
- Determinants of Image Quality of Heidelberg Retina Tomography II and Its Association with Optic Disc Parameters in a Population-based Setting Zheng Y, Cheung CY, Wong TY, Wong WL, Loon SC, Aung T Am J Ophthalmol. 2011 Apr; 151(4):663-70
- Metabolic syndrome components and age-related cataract: the Singapore Malay Eye Study Sabanayagam C, Wang JJ, Mitchell P, Tan AG, Tai ES, Aung T, Saw SM, Wong TY Invest Ophthalmol Vis Sci. 2011 Apr 14; 52(5):2397-404
- Prevalence and risk factors for refractive errors in Indians: the Singapore Indian Eye Study (SINDI) Pan CW, Wong TY, Lavanya R, Wu RY, Zheng YF, Lin XY, Mitchell P, Aung T, Saw SM Invest Ophthalmol Vis Sci. 2011 May 16; 52(6):3166-73.
- Impact of early and late age-related macular degeneration on vision-specific functioning Lamoureux EL, Mitchell P, Rees G, Cheung G, Yeo I, Lee SY, Liu E, Wong TY Br J Ophthalmol. 2011 May; 95(5):666-70
- Retinal vascular tortuosity, blood pressure, and cardiovascular risk factors Cheung CY, Zheng Y, Hsu W, Lee ML, Lau QP, Mitchell P, Wang JJ, Klein R, Wong TY Ophthalmology. 2011 May; 118(5):812-8
- Retinal arteriolar wall signs and early age-related macular degeneration: the Singapore Malay Eye Study Cheung CM, Cheung CY, Yang EL, Mitchell P, Wang JJ, Wong TY Am J Ophthalmol. 2011 Jul; 152(1):108-113
- Influence of refractive error on optic disc topographic parameters: the Singapore Malay Eye Study Wu RY, Wong TY, Zheng YF, Cheung CY, Perera SA, Saw SM, Aung T Am J Ophthalmol. 2011 Jul; 152(1):81-6
- Quantitative and Qualitative Retinal Microvascular Characteristics and Blood Pressure Cheung CY, Tay WT, Mitchell P, Wang JJ, Hsu W, Lee ML, Lau QP, Zhu AL, Klein R, Saw SM, Wong TY J Hypertens. 2011 Jul; 23(7):1380-91
- Cataract Prevalence varies substantially with Assessment Systems: Comparison of Clinical and Photographic Grading in a Population-based Study Tan AC, Wang JJ, Lamoureux EL, Wong W, Mitchell P, Li J, Tan AG, Wong TY Ophthalmic Epidemiol. 2011 Aug; 18(4):164-70
- Ocular biometry in an urban Indian population: the Singapore Indian Eye Study (SINDI) Pan CW, Wong TY, Chang L, Lin XY, Lavanya R, Zheng YF, Kok YO, Wu RY, Aung T, Saw SM Invest Ophthalmol Vis Sci. 2011 Aug 22; 52(9):6636-42
- Racial Differences in the Prevalence of Diabetes but Not Diabetic Retinopathy in a Multi-ethnic Asian Population Chiang PP, Lamoureux EL, Cheung CY, Sabanayagam C, Wong W, Tai ES, Lee J, Wong TY Invest Ophthalmol Vis Sci. 2011 Sep 29; 52(10):7586-92
- Prevalence and Causes of Visual Impairment and Blindness in an Urban Indian Population the Singapore Indian Eye Study Zheng Y, Lavanya R, Wu R, Wong WL, Wang JJ, Mitchell P, Cheung N, Cajucom-Uy H, Lamoureux E, Aung T, Saw SM, Wong TY Ophthalmology. 2011 Sep; 118(9):1798-804
- Literacy is an independent risk factor for vision impairment and poor visual functioning Zheng Y, Lamoureux EL, Chiang PP, Cheng CY, Anuar AR, Saw SM, Aung T, Wong TY Invest Ophthalmol Vis Sci. 2011 Sep 29; 52(10):7634-9
- Independent impact of area-level socioeconomic measures on visual impairment Zheng Y, Lamoureux E, Finkelstein E, Wu R, Lavanya R, Chua D, Aung T, Saw SM, Wong TY Invest Ophthalmol Vis Sci. 2011 Nov 11; 52(12):8799-805
- Hypertension, hypertension control, and chronic kidney disease in a Malay population in Singapore Sabanayagam C, Shankar A, Lim SC, Tai ES, Wong TY Asia Pac J Public Health. 2011 Nov; 23(6):936-45
- Differential Association of Retinal Arteriolar and Venular Caliber with Diabetes and Retinopathy Tsai AS, Wong TY, Lavanya R, Zhang R, Hamzah H, Tai ES, Cheung CY Diabetes Research and Clinical Practice. 2011 Nov; 94(2):291-8
- Determinants of quantitative optic nerve measurements using spectral domain optical coherence tomography in a population-based sample of non-glaucomatous subjects Cheung CY, Chen D, Wong TY, Tham YC, Wu R, Zheng Y, Cheng CY, Saw SM, Baskaran M, Leung CK, Aung T Invest Ophthalmol Vis Sci. 2011 Dec 20; 52(13):9629-35
- Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism Fan Q, Zhou X, Khor CC, Cheng CY, Goh LK, Sim X, Tay WT, Li YJ, Ong RT, Suo C, Cornes B, Ikram MK, Chia KS, Seielstad M, Liu J, Vithana E, Young TL, Tai ES, Wong TY, Aung T, Teo YY, Saw SM PLoS Genet. 2011 Dec; 7(12):e1002402
- The prevalence and risk factors of ocular trauma: the Singapore Indian Eye Study Chua D, Wong W, Lamoureux EL, Aung T, Saw SM, Wong TY Ophthalmic Epidemiol. 2011 Dec; 18(6):281-7
2010
- Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay Eye Study Lim LS, Saw SM, Jeganathan VS, Tay WT, Aung T, Tong L, Mitchell P, Wong TY Invest Ophthalmol Vis Sci. 2010 Jan; 51(1):103-9
- Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore Tan JT, Ng DP, Nurbaya S, Ye S, Lim XL, Leong H, Seet LT, Siew WF, Kon W, Wong TY, Saw SM, Aung T, Chia KS, Lee J, Chew SK, Seielstad M, Tai ES J Clin Endocrinol Metab. 2010 Jan; 95(1):390-7
- Prevalence and risk factors of retinopathy in an Asian population without diabetes: the Singapore Malay Eye Study Jeganathan VS, Cheung N, Tay WT, Wang JJ, Mitchell P, Wong TY Arch Ophthalmol. 2010 Jan; 128(1):40-5
- C-reactive protein and age-related macular degeneration and cataract: the Singapore Malay Eye Study Boey PY, Tay WT, Lamoureux E, Tai ES, Mitchell P, Wang JJ, Saw SM, Wong TY Arch Ophthalmol. 2010 Jan; 128(1):40-5
- Chronic kidney disease and intraocular pressure: the Singapore Malay Eye Study Nongpiur ME, Wong TY, Sabanayagam C, Lim SC, Tai ES, Aung T Ophthalmology. 2010 Mar; 117(3):524-30
- Are myopic eyes less likely to have diabetic retinopathy? Lim LS, Lamoureux E, Saw SM, Tay WT, Mitchell P, Wong TY Ophthalmology. 2010 Mar; 117(3):524-30
- Diagnostic ability of Heidelberg Retina Tomography in detecting glaucoma in a population setting: the Singapore Malay Eye Study Zheng Y, Wong TY, Lamoureux E, Mitchell P, Loon SC, Saw SM, Aung T Ophthalmology. 2010 Mar; 117(3):524-30
- Impact of diabetic retinopathy on vision-specific function Lamoureux EL, Tai ES, Thumboo J, Kawasaki R, Saw SM, Mitchell P, Wong TY Ophthalmology. 2010 Apr; 117(4):757-65
- C-reactive protein and microalbuminuria in a multi-ethnic Asian population Sabanayagam C, Lee J, Shankar A, Lim SC, Wong TY, Tai ES. C-reactive protein and microalbuminuria in a multi-ethnic Asian population Nephrol Dial Transplant. 2010 Apr; 25(4):1167-72
- The Prevalence of Age-related Macular Degeneration in Asians: A Systematic Review and Meta-Analysis Kawasaki R, Yasuda M, Song SJ, Chen SJ, Jonas JB, Wang JJ, Mitchell P, Wong TY Ophthalmology. 2010 May; 117(5):921-7
- Relationship of retinal vascular tortuosity with the neuroretinal rim: the Singapore Malay Eye Study Koh V, Cheung CY, Zheng Y, Wong TY, Wong W, Aung T Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3736-41
- Refractive error, axial dimensions, and primary open-angle glaucoma: the Singapore Malay Eye Study Perera SA, Wong TY, Tay WT, Foster PJ, Saw SM, Aung T Arch Ophthalmol. 2010 Jul; 128(7):900-5
- Distribution of ocular perfusion pressure and its relationship with open-angle glaucoma: the Singapore Malay Eye Study Zheng Y, Wong TY, Mitchell P, Friedman DS, He M, Aung T Invest Ophthalmol Vis Sci. 2010 Jul; 51(7):3399-404
- The prevalence of and risk factors for pterygium in an urban Malay population: the Singapore Malay Eye Study (SiMES) Cajucom-Uy H, Tong L, Wong TY, Tay WT, Saw SM Br J Ophthalmol. 2010 Aug; 94(8):977-81
- Smoking, socioeconomic factors, and age-related cataract: The Singapore Malay Eye Study Wu R, Wang JJ, Mitchell P, Lamoureux EL, Zheng Y, Rochtchina E, Tan AG, Wong TY Arch Ophthalmol. 2010 Aug; 128(8):1029-35
- Impact of symptomatic dry eye on vision-related daily activities: the Singapore Malay Eye Study Tong L, Waduthantri S, Wong TY, Saw SM, Wang JJ, Rosman M, Lamoureux E Eye (Lond). 2010 Sep; 24(9):1486-91
- Glycemic and blood pressure control in an Asian Malay population with diabetes and diabetic retinopathy Huang OS, Lamoureux EL, Tay WT, Tai ES, Wang JJ, Wong TY Arch Ophthalmol. 2010 Sep; 128(9):1185-90
- C-reactive protein, body mass index, and diabetic retinopathy Lim LS, Tai ES, Mitchell P, Wang JJ, Tay WT, Lamoureux E, Wong TY Invest Ophthalmol Vis Sci. 2010 Sep; 51(9):4458-63
- Cardiovascular risk factors, inflammation, and corneal arcus: the Singapore Malay Eye Study Wu R, Wang JJ, Tai ES, Wong TY Am J Ophthalmol. 2010 Oct; 150(4):581-587
- A new method to measure peripheral retinal vascular caliber over an extended area Cheung CY, Hsu W, Lee ML, Wang JJ, Mitchell P, Lau QP, Hamzah H, Ho M, Wong TY Microcirculation. 2010 Oct; 17(7):495-503
- Effect of corneal arcus on central corneal thickness, intraocular pressure, and primary open-angle glaucoma: the Singapore Malay Eye Study Wu R, Wong TY, Saw SM, Cajucom-Uy H, Rosman M, Aung T Arch Ophthalmol. 2010 Nov; 128(11):1455-61
- Influence of diabetes and diabetic retinopathy on the performance of Heidelberg retina tomography II for diagnosis of glaucoma Zheng Y, Wong TY, Cheung CY, Lamoureux E, Mitchell P, He M, Aung T Invest Ophthalmol Vis Sci. 2010 Nov; 51(11):5519-24
- Hyperopic refractive error and shorter axial length are associated with age-related macular degeneration: the Singapore Malay Eye Study Lavanya R, Kawasaki R, Tay WT, Cheung GC, Mitchell P, Saw SM, Aung T, Wong TY Invest Ophthalmol Vis Sci. 2010 Dec; 51(12):6247-52
2009
- Knowledge and beliefs associated with refractive errors and undercorrection: the Singapore Malay Eye Study Rosman M, Wong TY, Wong W, Wong ML, Saw SM Br J Ophthalmol. 2009 Jan; 93(1):4-10
- Socioeconomic status and microalbuminuria in an Asian population Sabanayagam C, Shankar A, Saw SM, Lim SC, Tai ES, Wong TY Nephrol Dial Transplant. 2009 Jan; 24(1):123-9
- Retinal microvascular caliber and chronic kidney disease in an Asian population Sabanayagam C, Shankar A, Koh D, Chia KS, Saw SM, Lim SC, Tai ES, Wong TY Am J Epidemiol. 2009 Mar 1; 169(5):625-32
- Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population Tai ES, Sim XL, Ong TH, Wong TY, Saw SM, Aung T, Kathiresan S, Orho-Melander M, Ordovas JM, Tan JT, Seielstad M J Lipid Res. 2009 Mar; 50(3):514-20
- Prevalence of cataract surgery and post-surgical visual outcomes in an urban Asian population: the Singapore Malay Eye Study Lavanya R, Wong TY, Aung T, Tan DT, Saw SM, Tay WT, Wang JJ. Br J Ophthalmol. 2009 Mar; 93(3):299-304
- A Questionnaire Based Assessment of Symptoms Associated with Tear Film Dysfunction and Lid Margin Disease in an Asian Population Tong L, Saw SM, Lamoureux EL, Wang JJ, Rosman M, Tan DT, Wong TY Ophthalmic Epidemiol. 2009 Mar-Apr; 16(2):142
- Central corneal thickness and its associations with ocular and systemic factors: the Singapore Malay Eye Study Su DH, Wong TY, Foster PJ, Tay WT, Saw SM, Aung T Am J Ophthalmol. 2009 Apr; 147(4):709-716
- Prevalence and risk factors of ocular trauma in an urban South-East Asian population: the Singapore Malay Eye Study Loon SC, Tay WT, Saw SM, Wang JJ, Wong TY Clin Experiment Ophthalmol. 2009 May; 37(4):362-7
- Relation of age-related cataract with obesity and obesity genes in an Asian population Lim LS, Tai ES, Aung T, Tay WT, Saw SM, Seielstad M, Wong TY Am J Epidemiol. 2009 May 15; 169(10):1267-74
- Variation of angle parameters in Asians: an anterior segment optical coherence tomography study in a population of Singapore Malays Amerasinghe N, Foster PJ, Wong TY, Htoon HM, He M, Shen SY, Aung HT, Saw SM, Aung T Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2626-31
- An evaluation of the reliability and validity of the visual functioning questionnaire (VF-11) using Rasch analysis in an Asian population Lamoureux EL, Pesudovs K, Thumboo J, Saw SM, Wong TY Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2607-13
- The impact of Corrected and Uncorrected Refractive Error on Visual Functioning: The Singapore Malay Eye Study Lamoureux EL, Saw SM, Thumboo J, Wee HL, Aung T, Mitchell P, Wong TY Invest Ophthalmol Vis Sci. 2009 Jun; 50(6):2614-20
- Peripheral Artery Disease and Glaucoma: The Singapore Malay Eye Study Jeganathan VS, Wong TY, Foster PJ, Crowston JG, Tay WT, Lim SC, Saw SM, Tai ES, Aung T Arch Ophthalmol. 2009 Jul; 127(7):888-93
- Population prevalence of tilted and torted optic discs among an adult Chinese population in Singapore: the Tanjong Pagar Study How AC, Tan GS, Chan YH, Wong TT, Seah SK, Foster PJ, Aung T Arch Ophthalmol. 2009 Jul; 127(7):894-9
- Prevalence and risk factors of undercorrected refractive errors among Singaporean Malay adults: the Singapore Malay Eye Study Rosman M, Wong TY, Tay WT, Tong L, Saw SM Invest Ophthalmol Vis Sci. 2009 Aug; 50(8):3621-8
- Quantitative retinal vascular calibre changes in diabetes and retinopathy: the Singapore Malay Eye Study Islam FM, Nguyen TT, Wang JJ, Tai ES, Shankar A, Saw SM, Aung T, Lim SC, Mitchell P, Wong TY Eye (Lond). 2009 Aug; 23(8):1719-24
- Relationship of retinal vascular caliber with retinal nerve fiber layer thickness: the Singapore Malay Eye Study Zheng Y, Cheung N, Aung T, Mitchell P, He M, Wong TY Invest Ophthalmol Vis Sci. 2009 Sep; 50(9):4091-6
- The association between socioeconomic status and overweight/obesity in a Malay population in Singapore Sabanayagam C, Shankar A, Saw SM, Tai ES, Wong TY Asia Pac J Public Health. 2009 Oct; 21(4):487-96
- Prevalence of diabetes mellitus, glycemic control, and associated factors in a Malay population in Singapore Sabanayagam C, Shankar A, Saw SM, Tai ES, Lim SC, Lee JJ, Wong TY Asia Pac J Public Health. 2009 Oct; 21(4):385-98
- Methodology of the Singapore Indian Chinese Cohort (SICC) Eye Study: quantifying ethnic variations in the epidemiology of eye diseases in Asians Lavanya R, Jeganathan VS, Zheng Y, Raju P, Cheung N, Tai ES, Wang JJ, Lamoureux E, Mitchell P, Young TL, Cajucom-Uy H, Foster PJ, Aung T, Saw SM, Wong TY Ophthalmic Epidemiol. 2009 Nov-Dec; 16(6):325-36
- Sociodemographic, lifestyle, and medical risk factors for visual impairment in an urban Asian population: the Singapore Malay Eye Study Chong EW, Lamoureux EL, Jenkins MA, Aung T, Saw SM, Wong TY Arch Ophthalmol. 2009 Dec; 127(12):1640-7
- Lack of awareness amongst community patients with diabetes and diabetic retinopathy: the Singapore Malay Eye Study Huang OS, Tay WT, Tai ES, Wang JJ, Saw SM, Jeganathan VS, Sandar M, Wong TY Ann Acad Med Singapore. 2009 Dec; 38(12):1048-55
- Relationship between glycated haemoglobin and microvascular complications: is there a natural cut-off point for the diagnosis of diabetes? Sabanayagam C, Liew G, Tai ES, Shankar A, Lim SC, Subramaniam T, Wong TY Diabetologia. 2009 Jul; 52(7):1279-89
2008
- Visual impairment, causes of vision loss, and falls: the Singapore Malay Eye Study Lamoureux EL, Chong E, Wang JJ, Saw SM, Aung T, Mitchell P, Wong TY Am J Ophthalmol. 2008 Mar; 145(3):43844
- Prevalence of pseudoexfoliation in Malay population in Singapore Sumasri K, Raju P, Aung T, Wong TY Am J Ophthalmol. 2008 Apr; 145(4):766-7
- Retinal vascular caliber, blood pressure, and cardiovascular risk factors in an Asian population: the Singapore Malay Eye Study Sun C, Liew G, Wang JJ, Mitchell P, Saw SM, Aung T, Tai ES, Wong TY Invest Ophthalmol Vis Sci. 2008 May; 49(5):1784-90
- Association between body mass index and chronic kidney disease in men and women: population-based study of Malay adults in Singapore Shankar A, Leng C, Chia KS, Koh D, Tai ES, Saw SM, Lim SC, Wong TY Nephrol Dial Transplant. 2008 Jun; 23(6):1910-8
- Diabetes, hyperglycemia, and central corneal thickness: the Singapore Malay Eye Study Su DH, Wong TY, Wong WL, Saw SM, Tan DT, Shen SY, Loon SC, Foster PJ, Aung T Ophthalmology. 2008 Jun; 115(6):964-968.e1
- Determinants of the optic cup to disc ratio in an Asian population: the Singapore Malay Eye Study (SiMES) Amerasinghe N, Wong TY, Wong WL, Mitchell P, Shen SY, Loon SC, Saw SM, Foster PJ, Aung T Arch Ophthalmol. 2008 Aug; 126(8):1101-8
- Prevalence and causes of low vision and blindness in an urban Malay population: the Singapore Malay Eye Study Wong TY, Chong EW, Wong WL, Rosman M, Aung T, Loo JL, Shen S, Loon SC, Tan DT, Tai ES, Saw SM Arch Ophthalmol. 2008 Aug; 126(8):1091-9
- The prevalence and types of glaucoma in Malay people: the Singapore Malay Eye Study Shen SY, Wong TY, Foster PJ, Loo JL, Rosman M, Loon SC, Wong WL, Saw SM, Aung T Invest Ophthalmol Vis Sci. 2008 Sep; 49(9):3846-51
- Prevalence of age-related macular degeneration in a Malay population: the Singapore Malay Eye Study Kawasaki R, Wang JJ, Aung T, Tan DT, Mitchell P, Sandar M, Saw SM, Wong TY Ophthalmology. 2008 Oct; 115(10):1735-41
- Prevalence and risk factors for refractive errors in the Singapore Malay Eye Survey Saw SM, Chan YH, Wong WL, Shankar A, Sandar M, Aung T, Tan DT, Mitchell P, Wong TY Ophthalmology. 2008 Oct; 115(10):1713-9
- Education, socio-economic status and age-related macular degeneration in Asians: the Singapore Malay Eye Study Cackett P, Tay WT, Aung T, Wang JJ, Shankar A, Saw SM, Mitchell P, Wong TY Br J Ophthalmol. 2008 Oct; 92(10):1312-5
- FTO variants are associated with obesity in the Chinese and Malay populations in Singapore Tan JT, Dorajoo R, Seielstad M, Sim XL, Ong RT, Chia KS, Wong TY, Saw SM, Chew SK, Aung T, Tai ES Diabetes. 2008 Oct; 57(10):2851-7
- Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study Wong TY, Cheung N, Tay WT, Wang JJ, Aung T, Saw SM, Lim SC, Tai ES, Mitchell P Ophthalmology. 2008 Nov; 115(11):1869-75
- Vision impairment, ocular conditions, and vision-specific function: the Singapore Malay Eye Study Lamoureux EL, Chong EW, Thumboo J, Wee HL, Wang JJ, Saw SM, Aung T, Wong TY Ophthalmology. 2008 Nov; 115(11):1973-81
- Retinal vascular caliber and age-related macular degeneration: the Singapore Malay Eye Study Jeganathan VS, Kawasaki R, Wang JJ, Aung T, Mitchell P, Saw SM, Wong TY Am J Ophthalmol. 2008 Dec; 146(6):954-9
- Smoking, cardiovascular risk factors, and age-related macular degeneration in Asians: the Singapore Malay Eye Study Cackett P, Wong TY, Aung T, Saw SM, Tay WT, Rochtchina E, Mitchell P, Wang JJ Am J Ophthalmol. 2008 Dec; 146(6):960-7
2007
- Socioeconomic status, systolic blood pressure and intraocular pressure: the Tanjong Pagar Study Yip JL, Aung T, Wong TY, Machin D, Khaw PT, Khaw KT, Seah S, Foster PJ Br J Ophthalmol. 2007 Jan; 91(1):56-61
- Rationale and methodology for a population-based study of eye diseases in Malay people: The Singapore Malay Eye Study (SiMES) Foong AW, Saw SM, Loo JL, Shen S, Loon SC, Rosman M, Aung T, Tan DT, Tai ES, Wong TY Ophthalmic Epidemiol. 2007 Jan-Feb; 14(1):25-35
- The relationship between anterior chamber depth and the presence of diabetes in the Tanjong Pagar Survey Saw SM, Wong TY, Ting S, Foong AW, Foster PJ Am J Ophthalmol. 2007 Aug; 144(2):325-6
- Socioeconomic status and overweight/obesity in an adult Chinese population in Singapore Sabanayagam C, Shankar A, Wong TY, Saw SM, Foster PJ J Epidemiol. 2007 Sep; 17(5):161-8
Cornea & refractive
Glaucoma, angle closure glaucoma
Myopia
Ocular inflammatory diseases
Retinal disease, diabetic retinopathy and AMD
Translational Clinical Research (TCR) Programme
Epidemiology
Ocular Imaging
Genetic Markers
Health and Service Science Research (HSSR)