Please note: There is an updated form of this web resource with more interactive elements, and new content! Come and visit Pathweb!

Neoplasia is an important topic. You will definitely encounter patients with neoplasms, either benign or malignant. Pathology plays a central role in the understanding of neoplasia.

Imagine this: Mr Chua is a 67 year old man with a chronic cough and a history of weight loss. He is a smoker, and CT scan of the thorax reveals a left lung mass.

A tissue sample (biopsy) is obtained and sent to the pathologist. The pathologist examines the tissue microscopically and writes a report (eg. benign or malignant tumour, tumour type). The clinician needs the report to decide on the next step. If the tumour is malignant, the next step is to find out the extent of disease (stage).

Diagnostic imaging is of key importance in the staging of malignant tumours. Once tumours are properly staged, decisions can be made on whether they can be removed surgically or whether chemo- or radiotherapy is required.

After the malignant tumour is removed, the pathologist again assesses the tumour and gives a ‘how bad is it’ report (prognosis), whereupon the decision on further treatment is made.

But first things first – you need to understand the inner workings of the cells in order to understand the process of neoplasia – what is neoplasia, how does it start; how to name, recognise and classify it before you can understand the effects on the patient. Later, when you are in the clinics and wards, you will learn how it is diagnosed, assessed and treated.

As you read more, you will discover some hidden exercises and quizzes.