Research

Research Interests

Probability, Statistics, Heuristic Optimization, Computational Biology, Forensic Science

Orcid 0000-0003-2373-1773

 

Selected Publications in Probability and Statistics

  1. K P Choi (1988). Some sharp inequalities for martingale transforms. Trans. Amer. Math. Soc., 307, 279-300.
  2. K P Choi (1992). A sharp inequality for martingale transforms and the unconditional basis constant of a monotone basis in $L^p (0,1)$. Trans. Amer. Math. Soc., 330, 509-529.
  3. Louis H. Y. Chen and K P Choi (1992). Some asymptotic and large deviation results in Poisson approximation. Ann. Probab., 20, 1867-1876.
  4. K P Choi (1994). On the medians of Gamma distributions and an equation of Ramanujan. Proc. Amer. Math. Soc., 121, 245-251.
  5. A. D. Barbour, Louis H. Y. Chen and K P Choi (1995). Poisson approximation for unbounded functions, I: independent summands. Statistica Sinica, 5, 749-766.
  6. K P Choi and Michael J. Klass (1997). Some asymptotically best possible prophet inequalities for convex functions of sums of independent variates and unordered martingale difference sequences. Ann. Probab., 25, 803-811.
  7. K P Choi and Aihua Xia (2002). Approximating the number of successes in independent trials: Binomial versus Poisson. Ann. Appl. Probab., 12, 1139-1148.
  8. A. D. Barbour and K P Choi (2004). A non-uniform bound for translated Poisson approximation. Electronic J. Probability, 9, 18-36.
  9. GJ Babu, ZD Bai, KP Choi, V Mangalam (2011). Limit theorems for functions of marginal quantiles. Bernoulli, 17(2), 671-686.
  10. ZD Bai, KP Choi, Y Fujikoshi (2018). Consistency of AIC and BIC in estimating the number of significant components in high-dimensional principal component analysis. Ann. Statist., 46(3), 1050-1076.
  11. ZD Bai, KP Choi, Y Fujikoshi (2018). Limiting Behavior of Eigenvalues in High-dimensional MANOVA via RMT. Ann. Statist., 46(6A), 2985-3013.
  12. XT Tong, KP Choi, TL Lai and WK Wong (2021). Stability bounds and almost sure convergence of improved particle swarm optimization methods. Research in Mathematical Sciences, 8 (2): Article 30.
  13. KP Choi, TL Lai, XT Tong and WK Wong (2021). A statistical approach to adaptive parameter tuning in nature-inspired optimization and optimal sequential design of dose-finding trials. Statistica Sinica, 31, 2381-2401.
  14. GTX Ang, ZD Bai, KP Choi, Y Fujikoshi and J Hu (2021). Exact and approximate computation of critical values of largest root test in high dimension. Communications in Statistics: Simulation and Computation. https://doi.org/10.1080/03610918.2021.1900247
  15. ZD Bai, KP Choi, Y Fujikoshi, J Hu (2022). Asymptotics of AIC, BIC and Cp Model Selection Rules in High-Dimensional Regression. Bernoulli, 28 (4), 2375–2403.
  16. Choi, K.P., Kam, E.H.H., Tong, X.T. et al. Appropriate noise addition to metaheuristic algorithms can enhance their performance. Scientific Reports 13, 5291 (2023). https://doi.org/10.1038/s41598-023-29618-5
  17. ZD Bai, KP Choi, Y Fujikoshi, J Hu (202?). KOO Approach for Scalable Variable Selection Problem in Large-Dimensional Regression. Statistica Sinica (to appear).

Selected Publications in Bioinformatics and Computational Biology

  1. K P Choi and Louxin Zhang (2004). Sensitivity analysis and efficient method for identifying optimal spaced seeds. J. Computer & System Sciences, 68, 22-40.
  2. K P Choi, Fanfan Zeng and Louxin Zhang (2004). Good spaced seeds for homology search. Bioinformatics, 20, 1053-1059.
  3. David S H Chew, K P Choi, Ming-Ying Leung and H. Heidner (2004). Palindromes in SARS and other coronaviruses. INFORMS J. on Computing, 16 (Special issue on Computational Biology/Bioinformatics), 331-340.
  4. Ming Ying Leung, K P Choi, Aihua Xia and Louis H. Y. Chen (2005). Nonrandom clusters of palindromes in herpesvirus genomes. J. Computational Biology, 12, 331-354.
  5. David S. H. Chew, K P Choi and Ming Ying Leung (2005). Scoring schemes of palindrome clusters for more sensitive prediction of replication origins in herpesviruses. Nucleic Acids Res., 33(15), e134.
  6. Kang Ning, K P Choi, Hon Wai Leong and Louxin Zhang (2005). A post-processing method for optimizing synthesis strategy for oligonucleotide microarrays. Nucleic Acids Res., 33(17), e144.
  7. F. Preparata, Louxin Zhang and K P Choi (2005). Quick, practical selection of effective seeds for homology search. J. Computational Biology, 12, 1137-1152.
  8. David S. H. Chew, Ming Ying Leung and K P Choi (2007). AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions. BMC Bioinformatics, 8:163.
  9. HH Do, KP Choi, FP Preparata, WK Sung, LX Zhang. (2008). Spectrum-based de novo repeat detection in genomic sequences. J. Computational Biology, 15, 469-487.
  10. J An, KP Choi, CA Wells, YPP Chen (2010). Identifying co-regulating microRNA groups. J. Bioinformatics and Computational Biology, 8, 99-115.
  11. R Cruz-Cano, David SH Chew, KP Choi, MY Leung (2010). Least-squares support vector machine approach to viral replication origin prediction. INFORMS J. on Computing, 22(3), 457-470.
  12. NH Tran, KP Choi, LX Zhang (2013). Counting Motifs in the Entire Biological Network from Noisy and Incomplete Data. Proceedings of the 17th Annual International Conference, RECOMB2013, Beijing, China, April 7-10, 2013 (Deng et al., Eds), Lecture Notes in Bioinformatics 7821, 269-270.
  13. S Li, KP Choi, T Wu (2013). Degree distribution of large networks generated by the partial duplication model. Theoretical Computer Science, 476, 94-108.
  14. NH Tran, KP Choi, LX Zhang (2013). Counting Motifs in the human interactome. Nature Communications, 4: 2241 doi:10.1038/ncomms3241.
  15. S Li, KP Choi, T Wu, LX Zhang (2013). Maximum likelihood inference of the evolutionary history of a PPI network from the duplication history of its proteins. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 10(6), 1412-1421.
  16. S Zhang, D Tian, NH Tran, KP Choi, LX Zhang (2014). Profiling the Transcription Factor Regulatory Networks of Human Cell Types. Nucleic Acids Res., 42(20), 12380-12387.
  17. K Lim, ZH Li, KP Choi, L Wong (2015). A quantum leap in the reproducibility, precision, and sensitivity of gene expression profile analysis even when sample size is extremely small. J. Bioinformatics and Computational Biology, 13(4), DOI: 10.1142/S0219720015500183
  18. T Wu, KP Choi (2016). On joint subtree distributions under two evolutionary models. Theoretical Population Biology, 108, 13-23.
  19. HWL Koh, F Damian, C Vogel, KP Choi, RM Ewing, HW Choi (2019). iOmicsPASS: network-based integration of multiomics data for predictive subnetwork discovery. npj Systems Biology and Applications.
  20. KP Choi, A Thompson, T Wu (2020).  On cherry and pitchfork distributions of random rooted and unrooted phylogenetic trees. Theoretical Population Biology, 132, 92-104.
  21. KP Choi, G Kaur, T Wu (2021). On asymptotic joint distributions of cherries and pitchforks
    for random phylogenetic trees. J Mathematical Biology, 83:4
  22. G Kaur, KP Choi, T Wu (2023). Distributions of cherries and pitchforks for the Ford model. Theoretical Population Biology, 149, 27–38.
  23. KP Choi, G Kaur, A Thompson, T Wu (2024). Distributions of 4-subtree patterns for uniform random unrooted phylogenetic trees. J. Theoretical Biology, 584, 111794.

 

Collaborative publications 

(a) Biomedical

  • A Chong, Z Zhang, K P Choi, V Choudhary, M B A Djamgoz, G Zhang and V B Bajic (2007). Promoter profiling and coexpression data analysis identifies 24 novel genes that are coregulated with AMPA receptor genes, GRIAs. Genomics, 89, 378-384.
  • GCH Koh, C Chen, A Cheong, BC Tai, KP Choi, NP Fong, KM Chan, BY Tan, R Petrella, A Thind, D Koh, KS Chia (2012). Trade-offs between effectiveness and efficiency in stroke rehabilitation. International J. Stroke, 7(8), 606-614.
  • BW Teo, PT Loh, WK Wong, PJ Ho, KP Choi, QC Toh, H Xu, S Saw, T Lau, S Sethi, EJC Lee (2015). Spot urine estimations are equivalent to 24-hour urine assessments of urine protein excretion for predicting clinical outcomes. International Journal of Nephrology, 2015, Article ID 156484.
  • YM Tan, Y Gao, G Teo, HWL Koh, ES Tai, CM Khoo, KP Choi, L Zhou, and HW Choi (2021). Plasma metabolome and lipidome associations with type 2 diabetes and diabetic nephropathy. Metabolites, 11 (4), 228.
  • Junlin Xu, Lingyu Cui, Jujuan Zhuang, Yajie Meng, Pingping Bing, Binsheng He, GengTian, Kwok Pui Choi, Taoyang Wu Bing Wang, JialiangYang (2022). Evaluating the performance of dropout imputation and clustering methods for single-cell RNA sequencing data. Computers in Biology and Medicine. https://doi.org/10.1016/j.compbiomed.2022.105697
  • Cook, AR, Choi, KP, Wong, WK (2022). Alex R. Cook, Kwok Pui Choi and Weng Kee Wong’s contribution to the `First Discussion Meeting on Statistical Aspects of the COVID–19 Pandemic’. J. Royal Statistical Society: Series A. https://doi.org/10.1111/rssa.12926

(b) Forensic Science

  • Kwok Pui Choi; Wei-Ling, Stella Tan; Shi-Yun Tan; Jessica Gunawan; Huilin Rochelle NG (2021). Profiling Fingerprint Patterns in Singapore across Race and Gender for Forensic Applications. Forensic Science Journal, 20 (1), 21-32.
  • Kwok Pui Choi, Stella Wei Ling Tan, Wenjie Fan, Jariah Bte Abdul Nassar, Mandi Suet Ning See, Shi Yun Tan (2022). Pedological studies of forensic soil evidence in Singapore using statistical approach. Forensic Science Journal, 21 (1), 27-36.

(c) Social Sciences

  • MYL Chiu, C Ghoh, G Chung, KP Choi (2019). Multistressed families in Singapore: A focus on transnational families. Children and Youth Services Review, 101, 372-382.

 

Book (editing) and Others

  • Louis HY Chen, KP Choi, JH Lou and KY Hu (1992). Probability Theory: Proceedings of the 1989 Singapore Probability Conference held at National University of Singapore, June 8-16, 1989, Walter De Gruyter & Co., Berlin.
  • KP Choi (2018). Sapere aude (Dare to know)! Interview of Moshe Y. Vardi. Imprints 32 Jul-Dec Issue