**Research Interests**

Probability, Statistics, Bioinformatics and Computational Biology, Forensic Science

**Publications in Probability and Statistics**

- K P Choi (1988). Some sharp inequalities for martingale transforms.
*Trans. Amer. Math. Soc.,***307**, 279-300. - K P Choi (1992). A sharp inequality for martingale transforms and the unconditional basis constant of a monotone basis in $L^p (0,1)$.
*Trans. Amer. Math. Soc.*,**330**, 509-529. - Louis H. Y. Chen and K P Choi (1992). Some asymptotic and large deviation results in Poisson approximation.
*Ann. Probab.*,**20**, 1867-1876. - K P Choi (1993). A remark on the inverse H\”{o}lder inequality.
*J. Math. Anal. Appl.*,**180**, 117-121. - F. F. Gan and K P Choi (1994). Computing average run length for exponential CUSUM schemes.
*J. Quality Tech.*,**26**, 134-143. - K P Choi (1994). On the medians of Gamma distributions and an equation of Ramanujan.
*Proc. Amer. Math. Soc.*,**121**, 245-251. - A. D. Barbour, Louis H. Y. Chen and K P Choi (1995). Poisson approximation for unbounded functions, I: independent summands.
*Statistica Sinica*,**5**, 749-766. - K P Choi and Michael J. Klass (1997). Some asymptotically best possible prophet inequalities for convex functions of sums of independent variates and unordered martingale difference sequences.
*Ann. Probab.*,**25**, 803-811. - K P Choi and Aihua Xia (2002). Approximating the number of successes in independent trials: Binomial versus Poisson.
*Ann. Appl. Probab.*,**12**, 1139-1148. - A. D. Barbour and K P Choi (2004). A non-uniform bound for translated Poisson approximation.
*Electronic J. Probability*,**9**, 18-36. - M Ghosh, KP Choi, J Li (2010). A commentary on the logistic distribution. In
*The Legacy of Alladi Ramakrishnan in the Mathematical Sciences*, (K. Alladi, J. Klauder and CR Rao, eds), Springer, 351-357. - GJ Babu, ZD Bai, KP Choi, V Mangalam (2011). Limit theorems for functions of marginal quantiles.
*Bernoulli*,**17**(2), 671-686. - J \”{A}rje, KP Choi, F Divino, K Meissner, S K\”{a}rkk\”{a}inen (2016). Understanding the Statistical Properties of the Percent Model Affinity Index Can Improve Biomonitoring Related Decision Making.
*Stochastic Environmental Research and Risk Assessment*,**30**(7), 1-28. - DC Tian, KP Choi (2013) Sharp Bounds and Normalization of Wiener-type Indices.
*PLoS One*,**8**(11): e78448 - WZ Toh, KP Choi, L Wong (2016). Redhyte: Towards a Self-diagnosing, Self-correcting, and Helpful Analytic Platform in
*Intelligent Information and Database Systems*, LNCS 9622, 3-12. - WZ Toh, KP Choi, L Wong (2017). Redhyte: a self-diagnosing, self-correcting, and helpful hypothesis analysis platform.
*J. Information and Telecommunication*,**1**(3), 241-258. - ZD Bai, KP Choi, Y Fujikoshi (2018). Consistency of AIC and BIC in estimating the number of significant components in high-dimensional principal component analysis.
*Ann. Statist.*,**46**(3), 1050-1076. - ZD Bai, KP Choi, Y Fujikoshi (2018). Limiting Behavior of Eigenvalues in High-dimensional MANOVA via RMT.
*Ann. Statist*.,**46**(6A), 2985-3013.

**Publications in Bioinformatics and Computational Biology**

- K P Choi and Louxin Zhang (2004). Sensitivity analysis and efficient method for identifying optimal spaced seeds.
*J. Computer & System Sciences*,**68**, 22-40. - K P Choi, Fanfan Zeng and Louxin Zhang (2004). Good spaced seeds for homology search.
*Bioinformatics*,**20**, 1053-1059. - David S H Chew, K P Choi, Ming-Ying Leung and H. Heidner (2004). Palindromes in SARS and other coronaviruses.
*INFORMS J. on Computing*,**16**(Special issue on Computational Biology/Bioinformatics), 331-340. - Ming Ying Leung, K P Choi, Aihua Xia and Louis H. Y. Chen (2005). Nonrandom clusters of palindromes in herpesvirus genomes. J. Computational Biology, 12, 331-354.
- K P Choi and Louxin Zhang (2005). Analysis of Spaced Seed Technique in Sequence Alignment.
*COSMOS*,**1**, 57-73. - David S. H. Chew, K P Choi and Ming Ying Leung (2005). Scoring schemes of palindrome clusters for more sensitive prediction of replication origins in herpesviruses.
*Nucleic Acids Res.*,**33**(15), e134. - Kang Ning, K P Choi, Hon Wai Leong and Louxin Zhang (2005). A post-processing method for optimizing synthesis strategy for oligonucleotide microarrays.
*Nucleic Acids Res*.,**33**(17), e144. - F. Preparata, Louxin Zhang and K P Choi (2005). Quick, practical selection of effective seeds for homology search.
*J. Computational Biology*,**12**, 1137-1152. - David S. H. Chew, Ming Ying Leung and K P Choi (2007). AT excursion: a new approach to predict replication origins in viral genomes by locating AT-rich regions.
*BMC Bioinformatics*,**8**:163. - HH Do, KP Choi, FP Preparata, WK Sung, LX Zhang. (2008). Spectrum-based de novo repeat detection in genomic sequences.
*J. Computational Biology*,**15**, 469-487. - J An, KP Choi, CA Wells, YPP Chen (2010). Identifying co-regulating microRNA groups.
*J. Bioinformatics and Computational Biology*,**8**, 99-115. - R Cruz-Cano, David SH Chew, KP Choi, MY Leung (2010). Least-squares support vector machine approach to viral replication origin prediction.
*INFORMS J. on Computing*,**22**(3), 457-470. - J Li, P Paramita, KP Choi, RKM Karuturi (2011). ConReg-R: Extrapolative recalibration of the empirical distribution of p-values to improve false discovery rate estimates.
*Biology Direct*,**6**:27 - J Li, KP Choi, Y Pawitan, RKM Karuturi (2012). Statistical significance assessment for biological feature selection. In
*Biological Knowledge Discovery Handbook: Preprocessing, Mining and Post-processing of Biological Data*(M Elloumi and AY Zomaya, eds), John Wiley & Sons, Inc. - J Li, KP Choi, RKM Karuturi (2012). Iterative piecewise linear regression to accurately assess statistical significance in batch confounded differential expression analysis.
*Lecture Notes in Bioinformatics*, volume 7292, Springer, 153-164. - S Li, KP Choi, T Wu, LX Zhang (2012). Reconstruction of network evolutionary history from extant network topology and duplication history.
*Lecture Notes in Bioinformatics*, volume 7292, Springer, 165-176. - NH Tran, KP Choi, LX Zhang (2013). Counting Motifs in the Entire Biological Network from Noisy and Incomplete Data.
*Proceedings of the 17th Annual International Conference, RECOMB2013, Beijing, China, April 7-10, 2013*(Deng et al., Eds), Lecture Notes in Bioinformatics 7821, 269-270. - S Li, KP Choi, T Wu (2013). Degree distribution of large networks generated by the partial duplication model.
*Theoretical Computer Science*,**476**, 94-108. - NH Tran, KP Choi, LX Zhang (2013). Counting Motifs in the human interactome.
*Nature Communications*,**4**: 2241 doi:10.1038/ncomms3241. - S Li, KP Choi, T Wu, LX Zhang (2013). Maximum likelihood inference of the evolutionary history of a PPI network from the duplication history of its proteins.
*IEEE/ACM Transactions on Computational Biology and Bioinformatics*,**10**(6), 1412-1421. - S Zhang, D Tian, NH Tran, KP Choi, LX Zhang (2014). Profiling the Transcription Factor Regulatory Networks of Human Cell Types.
*Nucleic Acids Res.*,**42**(20), 12380-12387. - K Lim, ZH Li, KP Choi, L Wong (2015). A quantum leap in the reproducibility, precision, and sensitivity of gene expression profile analysis even when sample size is extremely small.
*J. Bioinformatics and Computational Biology*,**13**(4), DOI: 10.1142/S0219720015500183 - T Wu, KP Choi (2016). On joint subtree distributions under two evolutionary models.
*Theoretical Population Biology*,**108**, 13-23. - HWL Koh, F Damian, C Vogel, KP Choi, RM Ewing, HW Choi (2019). iOmicsPASS: network-based integration of multiomics data for predictive subnetwork discovery.
*npj Systems Biology and Applications.*

**Collaborative publications **

*(a) Biomedical*

- A Chong, Z Zhang, K P Choi, V Choudhary, M B A Djamgoz, G Zhang and V B Bajic (2007). Promoter profiling and coexpression data analysis identifies 24 novel genes that are coregulated with AMPA receptor genes, GRIAs.
*Genomics*,**89**, 378-384. - GCH Koh, C Chen, A Cheong, BC Tai, KP Choi, NP Fong, KM Chan, BY Tan, R Petrella, A Thind, D Koh, KS Chia (2012). Trade-offs between effectiveness and efficiency in stroke rehabilitation.
*International J. Stroke*,**7**(8), 606-614. - BW Teo, PT Loh, WK Wong, PJ Ho, KP Choi, QC Toh, H Xu, S Saw, T Lau, S Sethi, EJC Lee (2015). Spot urine estimations are equivalent to 24-hour urine assessments of urine protein excretion for predicting clinical outcomes.
*International Journal of Nephrology*, 2015, Article ID 156484.

*(b) Social Sciences*

- MYL Chiu, C Ghoh, G Chung, KP Choi (2019). Multistressed families in Singapore: A focus on transnational families.
*Children and Youth Services Review*,**101**, 372-382.

**Book (editing) and Others
**

- Louis HY Chen, KP Choi, JH Lou and KY Hu (1992). Probability Theory: Proceedings of the 1989 Singapore Probability Conference held at National University of Singapore, June 8-16, 1989, Walter De Gruyter & Co., Berlin.
- KP Choi (2018). Sapere aude (Dare to know)! Interview of Moshe Y. Vardi.
*Imprints***32**Jul-Dec Issue