CHARGE Retinal vessels

The files below contain association summary statistics for the CHARGE retinal vessels meta-analysis, including AGES, ARIC, CHS, RS, and BMES.

Calibre retinal arteriole equivalent (CRAE): Sim X, Jensen RA, Ikram MK, Cotch MF, et al. Genetic loci for
retinal arteriolar microcirculation. PLoS One. 2013 Jun 12;8(6):e65804. PubMed PMID: 23776548; PubMed Central PMCID: PMC3680438.

Calibre retinal venular equivalent (CRVE): Ikram MK, Sim X, Jensen RA, Cotch MF, Hewitt AW, et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010 Oct 28;6(10):e1001184. PubMed PMID: 21060863; PubMed Central PMCID: PMC2965750.

Each file contains the following information:

  1. CHR: chromosome
  2. POS: position (hg19)
  3. MARKERNAME: RSID
  4. N: Total sample size
  5. EFF_ALLELE: Effect allele
  6. NONEFF_ALLELE: Other allele
  7. EFF_ALLELE_FREQ: Effect allele frequency
  8. BETA: Effect estimate
  9. SEBETA: Standard error of effect estimate
  10. P: P-value

CRAE
CRVE

References:

  1. Ikram MK et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 2010 Oct 28;6(10):e1001184. doi:10.1371/journal.pgen.1001184. PubMed PMID: 21060863; PubMed Central PMCID: PMC2965750.
  2. Sim X et al. Genetic loci for retinal arteriolar microcirculation. PLoS One. 2013 Jun 12;8(6):e65804. doi: 10.1371/journal.pone.0065804. Print 2013. PubMed PMID: 23776548; PubMed Central PMCID: PMC3680438.

Please refer any queries to Dr Xueling Sim (ephsx@nus.edu.sg)