Dementia Research Notes

Dementia Research Notes

Lai Lab, Dept Pharmacology, NUS
November 14

Thought of the Day


© 2014 Lai Lab, NUS. All rights reserved.

Posted November 14, 2013 by Mitchell Lai in category Musings & Other Notes

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The Danger of Mis-translation Hot Off the Press: Decreased rabphilin 3A immunoreactivity in Alzheimer’s Disease is associated with Aβ burden
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  • The Team
  • Collaborators
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  • Research Interests
    • Dementia “Omics” and Biomarkers
    • Dementia Neurochemistry
    • Neuroinflammation
    • Neurotransmission, Cell signaling, Amyloid and Tau
  • Research Publications
    • Papers (2012 – Current)
    • Papers (2001-2011)
  • Teaching

Blog categories

  • Hot Off the Press: Lysosomal cathepsin D is upregulated in Alzheimer’s disease neocortex and may be a marker for neurofibrillary degeneration
  • Hot Off the Press: Serum hepatocyte growth factor is associated with small vessel disease in Alzheimer’s dementia
  • Congratulations to Dr Julie Yanan Zhu
  • Hot Off the Press: Mitochondrial translocase of the outer membrane (TOM) alterations may underlie dysfunctional oxidative phosphorylation in Alzheimer’s disease
  • Hot Off the Press: An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias
  • The downside of a background in pharmacology
  • Hot Off the Press: Selective induction of alternatively spliced FynT isoform by TNF facilitates persistent inflammatory responses in astrocytes
  • Hot Off the Press: Serum IL-8 is a marker of white-matter hyperintensities in patients with Alzheimer’s disease
  • Hot Off the Press: Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK
  • Hot Off the Press: Increased phosphorylation of collapsin response mediator protein-2 at Thr514 correlates with β-amyloid burden and synaptic deficits in Lewy body dementias

Disclaimer

This is a blog.nus website whose primary aim is to give an overview of my research and teaching activities to students and other interested parties. All views, opinions and comments on this site do not necessarily reflect those of the National University of Singapore or its affiliates. - Mitchell Lai



© 2014 Lai Lab, NUS. All rights reserved.
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