Nanomaterials induced endothelial leakiness (NanoEL)
Nanomaterials causes endothelial cell leakiness. Novel concept of crossing the endothelial cell barriers.
F Peng^, MI Setyawati^, JK Tee^, X Ding, J Wang, ME Nga, HK Ho*, DT Leong*. Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness. Nature Nanotechnology. 2019. 14, 279–286.
Setyawati MI, Tay CY, Chia SL, Goh SL, Fang W, Neo MJ, Chong HC, Tan SM, Loo SC, Ng KW, Xie JP, Ong CN, Tan NS, Leong DT*. TiO2 nanomaterials cause endothelial cell leakiness by disrupting the homophilic interaction of VE-cadherin. Nature Communications. 2013. 4, 1673.
JK Tee, MI Setyawati, F Peng, DT Leong*, HK Ho*. Angiopoietin-1 accelerates restoration of endothelial cell barrier integrity from nanoparticle-induced leakiness. Nanotoxicology. 2019. DOI: 10.1080/17435390.2019.1571646.
F Peng, JK Tee, MI Setyawati, X Ding, HLA Yeo, YL Tan, DT Leong*, HK Ho*. Inorganic Nanomaterials as Highly Efficient Inhibitors of Cellular Hepatic Fibrosis. ACS Applied Mat Interfaces 2018, 10, 31938–31946.
Setyawati MI, Tay CY, Docter D, Stauber RH, Leong DT*. Understanding and Exploiting Nanoparticles’ Intimacy with the Blood Vessel and Blood. Chemical Society Reviews 2015, 44, 8174-8199. (RSC Gold for Gold – open access)