Postdoctoral Fellows.

1. Xiang Ping, Ph.D. 2016-2020

 

Graduate Students.

1. Madhumathi Thirunavukkarasan, Ph.D. “Characterizing the role of free fatty acid receptors (FFARs) in breast cancer cells.” (NUS, 2017)
2. Angad Rao, Ph.D. “Evaluating the therapeutic potential of orphan G protein-coupled receptors: GPR19 and GPR17.” (NUS, 2017)
3. Malavika Srikanth, Ph.D. “Role of PLA₂-derived bioactive lipids in Neuroinflammation.” (NUS, 2019)
4. Wang Wei, Ph.D. “Roles of sphingosine 1-phosphate receptor 2 (S1P₂) in neural and cancer cells: implications for prevention of cisplatin-induced peripheral neuropathy.” (NUS, 2019)

 

Research Assistants.

1. Seow Wei Lun, Mark. 2016-2018
2. Siti Nasuha Binte Abdul Karim. 2017-2018
3. Goh Zi Ning Louise. 2018-2019
4. Yam Ting Yu Amelia. 2019-2020

 

Undergraduate Students.

1. Lee Yenn Ting Charmaine, B.Sc. (NUS, 2013), Undergraduate honors research. “Free Fatty Acid Receptor 1 Promotes Proliferation and Migration of Breast Cancer Cells.”
2. Abrar Siddiquee, B.Sc. (NUS, 2014), Undergraduate honors research. “Free Fatty Acid Receptor 2 Promotes Proliferation and Metastasis of MCF7 Breast Cancer cells.”
3. Lim Siew Mon, B.Sc. (NUS, 2014), Undergraduate honors research. “Evaluating LPA₁ as treatment for inflammatory pain.”
4. Mohamed Ally Ibrahim, B.Sc. (NUS, 2015), Undergraduate honors research. “Free Fatty Acid Receptor 3 Reduces Proliferation and Metastasis of MCF7 Breast Cancer cells.”
5. Lim Shilei Ella, B.Sc. (NUS, 2015), Undergraduate honors research. “The effect of S1P₂ agonist, CYM-5478, on OC-k3 cells and its potential role in hearing loss.”
6. Lam Yue Ning, B.Sc. (NUS, 2015), Undergraduate honors research. “Comparison of Different Methods for the Directed Differentiation of Human Induced Pluripotent Stem Cells into Renal Proximal Tubular-Like Cells.”
7. Reolo Marie Jennifer Yan, B.Sc. (NUS, 2015), Undergraduate research. “Cytoprotective role of S1PR₂ agonist, CYM-5478, in rat glioma C6 cells: cochlear maintenance model.”
8. Hee Yan Ting, B.Sc. (NUS, 2015), Undergraduate research. “Using Calcium Imaging to Validate Antagonists of LPA₁.”
9. Tan Hui Min, B.Sc. (NUS, 2015), Undergraduate research. “Characterization of FFAR1 using TGFα Shedding Assay.”
10. Ang Huili, B.Sc. (NUS, 2015), Undergraduate research. “Characterization of FFAR1 allosteric site and its involvement with glucose in type two diabetes.”
11. Andreas Alvin Purnomo Soetedjo, B.Sc. (NUS, 2016), Undergraduate honors research. “Generation and Characterization of Antibodies Targeting G-Protein-Coupled Receptors: GPR17 and S1P₃.”
12. Camelia Ortega, B.Sc. (NUS, 2016), Undergraduate honors research. “Investigating the role of Free Fatty Acid Receptor 1 in Epithelial-Mesenchymal Transition in Breast Cancer Cells.”
13. Chua Xin Ying, B.Sc. (NUS, 2016), Undergraduate honors research. “Sphingosine 1-phosphate: a Potential Diagnostic Biomarker for Vascular Dementia.” (Co-supervised by Mitchell P. Lai)
14. Teo Yuan Ru, B.Sc. (NUS, 2016), Undergraduate honors research. “Possible Roles of Free Fatty Acid Receptors 2 and 3 in Breast Cancer Development.”
15. Peh Yee Xin, B.Sc. (NUS, 2016), Undergraduate honors research. “Cytoprotective Role of Sphingosine 1-Phosphate Receptor 2 Agonist (CYM-5478), Against Cisplatin, an Ototoxic Drug.”
16. Reolo Marie Jennifer Yan, B.Sc. (NUS, 2016), Undergraduate honors research. “Sphingosine 1-phosphate receptor 2 (S1P₂) protects cochlear integrity by attenuating reactive oxygen species generation.”
17. Zhao Xinyuan, B.Sc. (NUS, 2017), Undergraduate honors research. “The anti-inflammatory effect of Souvenaid in the brain mediated through DHA and its metabolites.”
18. Ang Hui Li, B.Sc. (NUS, 2017), Undergraduate honors research. “Mechanism Of Deregulated Sphingosine 1-Phosphate Signaling In Neurological Diseases.”
19. Sim Poh Khee, B.Sc. (NUS, 2017), Undergraduate honors research. “HCAR₁ exhibits anti-proliferative effect and does not confer tamoxifen resistance in MCF-7 cells.”
20. Lam Wan Shing Brenda, B.Sc. (NUS, 2018), Undergraduate honors research. “New insights into the metabolism of non-canonical sphingolipids.”
21. Goh Zi Ning Louise, B.Sc. (NUS, 2018), Undergraduate honors research. “Examining the role of bioactive lipids in the link between obesity and diabetes.”
22. P Santhia, B.Sc. (NUS, 2018), Undergraduate honors research. “Characterizing the roles of bioactive lipids in inflammation.”
23. Kalashobini D/O Chandrasaharan, B.Sc. (NUS, 2018), Undergraduate honors research. “Characterizing the neuroinflammatory responses to bioactive lipids.”
24. Tejasvene Ramesh, B.Sc. (NUS, 2019), Undergraduate honors research. “Exploring the role of S1P₂ in Vascular dementia.”
25. Noor Rashidha Bte Meera Sahib, B.Sc. (NUS, 2019), Undergraduate honors research. “Novel screening assays for anti-inflammatory compounds.”
26. Janice Lian Hui Min, B.Sc. (NUS, 2019), Undergraduate honors research. “Development and application of a novel screening assay for GPCR targeted drugs.”
27. Leong Hui Lin Kathleen, B.Sc. (NUS, 2019), Undergraduate honors research. “Developing STAT3 Inhibitor Screening Assays for Drug Development.”
28. Duryakshini Gurusamy, B.Sc. (NUS, 2019), Undergraduate honors research. “Screening natural product libraries to identify new drug candidates for airway inflammation.”
29. Lay Jing Rong Priscilla, B.Sc. (NUS, 2019), Undergraduate honors research. “Establishing novel screening assays for anti-neuroinflammatory compounds.”
30. Neville Cheong Kar Sang, B.Sc. (NUS, 2019), Undergraduate honors research. “Screening Natural Product Libraries For Novel Inhibitors of CCL5.”
31. Yam Ting Yu Amelia, B.Sc. (NUS, 2019), Undergraduate honors research. “Characterising a novel neuroinflammatory pathway mediated by DHA Metabolism.”
32. Chang Jing Kai, B.Sc. (NUS, 2019), Undergraduate honors research. “Validation and Drug-Design for Sphingosine 1-Phosphate Receptor 2 (S1P₂) Targeted Therapeutics.”

 

Exchange Students.

1. Abraham Sterling, B.Sc. (UNC-CH, U.S.A., 2013), Undergraduate research. “Exploration of the Effects of LCFFAs in relations to FFARs in the MDA-MB-231 and OVK18 cell lines.”
2. Lam Wan Shing Brenda, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2013), “Development of aptamers as drug candidates for cell surface receptors.”
3. Selina Setiadi Wong, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2013), “Development of aptamers as drug candidates for cell surface receptors.”
4. Julia Han Noll, B.Sc. (University of Heidelberg, Germany, 2013), Undergraduate research. “Targeting lipid receptors for the treatment of cancer.”
5. Koh Pei Pei, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2014), “Isolation of therapeutic aptamers through SELEX against LPAR1 in neuropathic pain.”
6. Jolene Sim, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2014), “Isolation of therapeutic aptamers through SELEX against LPAR1 in neuropathic pain.”
7. Joel Chan, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2014), “Developing and Characterising Biologics for Chronic Pain Treatment via LPA₁-mediated pathway.”
8. Siti Shahirah, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2014), “Developing and Characterising Biologics for Chronic Pain Treatment via LPA₁-mediated pathway.”
9. Sarah Underwood, B.Sc. (UNC-CH, U.S.A., 2014), Undergraduate research. “Evaluating the effects of lipid signaling on cancer cells by immunocytochemistry.”
10. Tim Lohoff, B.Sc. (University of Bielefeld, Germany, 2014), Undergraduate research. “Evaluation of free fatty acid signaling in breast cancer cells.”
11. Nicole Isabella Tan Yi Zhen, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2015), “Validation and Characterization of Candidate LPA₁ binding
    Aptamers for Treating Neuropathic Pain.”
12. Low Hui Ching Shannon, Biomedical Science Diploma (Ngee Ann Polytechnic, Singapore, 2015), “Validation and Characterization of Candidate LPA₁ binding
    Aptamers for Treating Neuropathic Pain.”
13. Michael Liu, B.Sc. (University of Toronto, Canada, 2015), Undergraduate research. “The effect of FFAR1 on MDF-7 sensitivity to chemotherapeutic drugs.”
14. Boi Linh Truong, B. Sc. (Ruprecht-Karls-Universität Heidelberg, Germany, 2015), Undergraduate research. “Characterization of FFAR1 signaling in breast cancer cells.”
15. Vidisha Singh, B.Sc. (University of Toronto, Canada, 2016), Undergraduate research. “The cytoprotective role of CYM-5478 against serum starvation.”
16. Heng Hui Li, Ph.D. candidate (University of Malaya, Malaysia, 2016), Graduate thesis project, “Characterization of novel drug compounds for adrenergic and serotonergic receptors.”
17. Lee Hui Min Jasmine, Biomedical science diploma (Ngee Ann Polytechnic, 2016) “Characterization of Novel Drugs that target G Protein-Coupled Receptors using Transforming Growth Factor Alpha Shedding Assay.”
18. Nicholas Hay Wei Jie, Biomedical science diploma (Ngee Ann Polytechnic, 2016), “Characterization of Novel Drugs that target G Protein-Coupled Receptors using Transforming Growth Factor Alpha Shedding Assay.”
19. Muhammad Adam Ihsan Boon Jia Sheng, Biomedical science diploma (Ngee Ann Polytechnic, 2017), “Detecting Signalling Bias in Sphingosine-1-Phosphate Receptors.”
20. Ryan Wong, Biomedical science diploma (Ngee Ann Polytechnic, 2017), “Detecting Signalling Bias in Sphingosine-1-Phosphate Receptors.”
21. Tatsuma Hind, (University of British Columbia, Vancouver, Canada, 2017), “Characterization/de-orphanization of GPR19.”
22. Phaedra Tan Ci Hui, Biomedical science diploma (Ngee Ann Polytechnic, 2018), “Engineering reliable and sensitive biosensors for the detection of CB1 receptor and caspase-1 activity.”
23. Lim Ching Yee Carine, Biomedical science diploma (Ngee Ann Polytechnic, 2018), “Engineering reliable and sensitive biosensors for the detection of CB1 receptor and caspase-1 activity.”
24. Nafeesah Bte Mohamed Ibrahim, Research Intern (NUS). 05/2018 – 08/2018.
25. Mia Vega (Pennsylvania State University, 2019). “Molecular characteristics of DHA-induced pyroptosis in BV2 microglial cells.”
26. Lovelight Jonah (University of Kansas, 2019). “Molecular characteristics of DHA-induced pyroptosis in BV2 microglial cells.”
27. Anabel Chang Jia Wei (Ngee Ann Polytechnic, honors research). “Examining the role of d18:1 and d16:1 sphingosine 1-phosphate in modulation of hypothalamic insulin sensitivity.”
28. Maxino Leanette Torres (Ngee Ann Polytechnic, honors research). “Examining the role of d18:1 and d16:1 sphingosine 1-phosphate in modulation of hypothalamic insulin sensitivity.”