Our Projects

Health Technology Assessment and Economic Evaluation (HTA)


  1. Early HTA of novel, non‐invasive serum microRNA test for early detection of gastric cancer – To adopt a data‐driven decision‐tree model for evaluating the cost‐utility and returns‐on‐investment of a microRNA test for gastric cancer screening, and to assess the range of implementation scenarios to identify most favourable setting to yield cost‐effective impact
  2. Cost‐effectiveness of oral vs IV antibiotics for Klebsiella liver abscess treatment – To evaluate cost‐ effectiveness of different mode of antibiotics delivery, with primary data on patient/hospital costs over 12 weeks and through assessment of QoL
  3. Economic burden of regulation to prevent harm – To cost the resources for detection of serious harm, analysis of root causes and “loop closing” to prevent recurrence in an AMC, by collecting/analyzing cost data between 2002‐2013 for serious reportable events
  4. Economic evaluation of improved structured clinical handover processes to ensure patient safety – To estimate economic impact of a structured clinical handover process to reduce sentinel events, by comparing benefits and costs from the intervention (including improvements in patient outcomes due to improvement in patient management), and evaluate the factors linked to handover‐driven events


Data Science and Analytics


  1. Profiling patients with T2DM in an AMC with poor outcomes and developing predictors among these patients: a formative study using hospital administrative databases – To identify factors associated with higher hosp. costs, repeated admissions and longer length of stay with T2DM, and to develop a prediction model through data‐mining the NUH administrative data related to healthcare cost and utilization
  2. Factors associated with glycemic control trajectories in T2D – To characterize trajectories of HbA1c for T2D patients using demographic and clinical characteristics, subsidy status and health service utilization information, through data‐mining NUH clinical data for variables associated with glycemic control
  3. Outcomes of adult ECMO for community acquired pneumonia, poisoning and overdose in adult patients – To evaluate the risk factors for outcomes in adult ECMO patients of the three above conditions, through retrospective data‐mining the ECMO registry
  4. Shared Care: Integrating rheumatology care in the community – To identify predictors for successful shared‐care / right‐siting of patients from tertiary hospitals to primary/community care, through analyzing the information generated from nine private family physicians and the period to first‐return to tertiary hospital setting
  5. Cross-Cultural Issues in Stroke: Policy, Population and Clinical Comparisons- An international comparison of stroke data from Singapore (SIN), the United States of America (US) and Australia (AUS) under the Global Aging Initiative looking at:
    • Trajectory of recovery indices over time
    • Registry comparison
    • Trajectory of Functional Recovery Effectiveness (FREs) and Efficiency (FREy) over time


Health Services Research


  1. Measuring integrated care within NUHS RHS – To adapt the Netherlands integrated care measure consisting of 59 items (over 6 domains of integration) for a pilot of 50 individuals involved in the   development / implementation of NUHS RHS, in order to provide baseline measurements for evaluating the RHS
  2. NUHS Outpatient Telehealth Initiative – To access the willingness of ~800 NUH outpatients patients with chronic hypertension, diabetes or heart failure to pay for tele-monitoring of vital signs, as an alternative to visits to the physicians in NUHS measured via the double‐bounded dichotomous choice method and to access their satisfaction with an adjusted version of the Telemedicine Satisfaction and Usefulness Questionnaire
  3. Evaluation of NUHS RHS programmes
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