Welcome!

I am an Associate Professor jointly appointed by the Centre for Quantitative Medicine, Duke-NUS Medical School, and the Department of Statistics and Applied Probability at the National University of Singapore. I also hold an Adjunct Associate Professor position with the Department of Biostatistics and Bioinformatics at Duke University, USA. At Duke-NUS, I have previously served as the Director of the Centre for Quantitative Medicine during 2014-2018, and also as the founding Co-director of the PhD program in Integrated Biostatistics and Bioinformatics, first of its kind in Singapore.

Prior to joining Duke-NUS in 2013, I was an Assistant Professor at the Department of Biostatistics, Columbia University, USA during 2009-2013. Previously, I had completed my Master of Statistics degree from the Indian Statistical Institute, Kolkata, India, and then my PhD in Statistics from the University of Michigan, Ann Arbor, USA, under the supervision of Prof. Susan A. Murphy. Here is a copy of my dissertation.

Research Interests

My primary research interest lies in developing statistical methods to facilitate data-driven personalized medicine in a time-varying setting, specifically in the area of dynamic treatment regimes (DTRs) or adaptive interventions. DTRs are decision rules about recommended treatments based on past treatment and time-varying patient characteristics. Once developed, these treatment regimes can be employed as decision support systems for clinicians, and are deemed as a key element of the chronic care model of health care. Jointly with Dr. Erica E.M. Moodie, I wrote the first textbook on this cutting-edge topic, published by Springer Inc., New York, in August 2013.

I have strong interest and expertise in modern clinical trial designs, including sequential multiple-assignment randomized trials (SMARTs) for DTRs, various types of adaptive designs, and multiphase optimization strategy (MOST) for developing multicomponent interventions using fractional factorial designs.

More recently, I got deeply interested in mobile health interventions and associated micro-randomized trials (MRTs), as well as analysis of big electronic health records data using machine learning tools. I have recently organized a thematic workshop on Statistical Methods for Developing Personalized Mobile Health Interventions hosted by the NUS Institute of Mathematical Sciences in February 2019.

Here is the link to my Google Scholar citation page.

And  here is a recent newspaper article on personalized smoking reduction strategies, co-authored by my PhD student Yan Xiaoxi and myself.